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anti-Hematopoietically Expressed Homeobox (HHEX) Antibodies

HHEX encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Additionally we are shipping Hematopoietically Expressed Homeobox Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HHEX 3087 Q03014
HHEX 15242 P43120
HHEX 79237  
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Top anti-Hematopoietically Expressed Homeobox Antibodies at antibodies-online.com

Showing 10 out of 107 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-HHEX Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: K562 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-HHEX Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: 293T cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse Un-conjugated WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HHex (RC204815) (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-HHex. Hex antibody (4B7) at 1:1000 with Lysates from HEK-293T cells transfected with human Hex expression vector 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IF, WB Anti-HHex mouse monoclonal antibody (ABIN2452344) immunofluorescent staining of HeLa cells transiently transfected by pCMV6-ENTRY HHex (RC204815) Hex antibody (2H7) at 1:100 dilution + Lysates from HEK-293T cells transfected with human Hex expression vector 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA Human Breast (formalin-fixed, paraffin-embedded) stained with HHEX antibody ABIN364468 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated WB HHEX Antibody (C-term)  western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the HHEX antibody detected the HHEX protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to HHEX on HeLa cell (antibody concentration 10 µg/mL). Western Blot analysis of HHEX expression in transfected 293T cell line by HHEX monoclonal antibody (M02), clone 1A5. Lane 1: HHEX transfected lysate(30.02 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details

HHEX Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Hematopoietically Expressed Homeobox Antibodies

  1. Cow (Bovine) Polyclonal HHEX Primary Antibody for IHC, WB - ABIN2777302 : Minami, Murakami, Horiuchi, Miura, Noguchi, Miyazaki, Hamakubo, Aird, Kodama: Interaction between hex and GATA transcription factors in vascular endothelial cells inhibits flk-1/KDR-mediated vascular endothelial growth factor signaling. in The Journal of biological chemistry 2004 (PubMed)

  2. Cow (Bovine) Polyclonal HHEX Primary Antibody for WB - ABIN2787509 : Hertel, Johansson, Raeder, Midthjell, Lyssenko, Groop, Molven, Njølstad: Genetic analysis of recently identified type 2 diabetes loci in 1,638 unselected patients with type 2 diabetes and 1,858 control participants from a Norwegian population-based cohort (the HUNT study). in Diabetologia 2008 (PubMed)

More Antibodies against Hematopoietically Expressed Homeobox Interaction Partners

Xenopus laevis Hematopoietically Expressed Homeobox (HHEX) interaction partners

  1. Data show that knockdown of hematopoietically expressed homeobox (hhex) resulted in a down-regulation of ventral pancreatic precursor 1 (vpp1 (show ATP6V0A1 Antibodies)) expression and a specific loss of the ventral pancreas.

  2. A gene regulatory network controlling hhex transcription in the anterior endoderm of the organizer.

Human Hematopoietically Expressed Homeobox (HHEX) interaction partners

  1. Data suggest that hematopoietically expressed homeobox protein (HHEX) downmodulation by promyelocytic leukemia (show PML Antibodies)-retinoic acid receptor alpha (show RARA Antibodies) fusion oncoprotein (PML (show PML Antibodies)-RARalpha (show RARA Antibodies)) is a key event during acute promyelocytic leukemia (show PML Antibodies) (APL (show FASL Antibodies)) pathogenesis.

  2. Hhex binds to the Cdkn2a (show CDKN2A Antibodies) locus and directly interacts with the Polycomb (show CBX2 Antibodies)-repressive complex 2 (PRC2) to enable H3K27me3-mediated epigenetic repression

  3. Data suggest that Hhex is a novel regulator of c-Myc (show MYC Antibodies) function that limits c-Myc (show MYC Antibodies) activity in transformed cells.

  4. PRH controls the migration of multiple epithelial cell lineages in part at least through the direct transcriptional regulation of Endoglin (show ENG Antibodies)

  5. HHEX promotes hepatic specification by repressing EOMES (show EOMES Antibodies) expression.

  6. Data indicate the potential importance of CDKAL1 (show CDKAL1 Antibodies) protein and homeobox protein HHEX in glucose homeostasis in this Alaska Native population with a low prevalence of type 2 diabetes (T2D).

  7. In all the CHD (show CHDH Antibodies) patients, we did not find any causative mutations in the coding region of the HHEX gene.

  8. Tissue-specific knockdown of the HHEX ortholog dHHEX (CG7056) directed metabolic defects and enhanced lethality; for example, fat-body-specific loss of dHHEX led to increased hemolymph glucose and reduced insulin (show INS Antibodies) sensitivity

  9. In conclusion, this epistatic interaction showed a high degree of consistency when stratifying by sex, the epsilon4 allele of apolipoprotein E (show APOE Antibodies) genotype, and geographic region.

  10. Data indicate associations of SNPs in eight loci CXCR4, HHEX, FOXA2, NGN3, TCF7L2, FLJ39370 (C4orf32), LOC646279 (RPL21P7) and THADA with body mass index (BMI) and weight.

Mouse (Murine) Hematopoietically Expressed Homeobox (HHEX) interaction partners

  1. Hhex(-/-) mESCs fail to differentiate from definitive endoderm to hepatic endoderm.

  2. results implicate Hhex in the maintenance of LT-HSCs and in lineage allocation from multipotent progenitors especially in stress hematopoiesis.

  3. Data suggest that Hhex is a novel regulator of c-Myc (show MYC Antibodies) function that limits c-Myc (show MYC Antibodies) activity in transformed cells.

  4. Hhex regulates Kit to promote radioresistance of self-renewing thymocytes in Lmo2 (show LMO2 Antibodies)-transgenic mice.

  5. Hhex is a key regulator of early lymphoid development, functioning, at least in part, via regulation of the cell cycle.

  6. Hhex and Cer1 (show CER1 Antibodies) are indispensable components of the Sox17 (show SOX17 Antibodies) pathway for cardiopoiesis.

  7. Hhex as the first transcriptional regulator specifically required for islet delta cells and suggest compromised paracrine control as a contributor to T2DM

  8. Data suggest that GPC3 (show GPC3 Antibodies) down-regulates hepatocyte proliferation by binding to hedgehog (show SHH Antibodies) (HH) and down-regulating the HH signaling pathway and binding with CD81 (show CD81 Antibodies), thus making it unavailable to bind to Hhex and causing its nuclear translocation.

  9. Hex expression and subcellular localization are associated with chondrocyte maturation

  10. Loss of Hhex is associated with reduction in hematopoietic maturation accompanied by reduced proliferation.

Zebrafish Hematopoietically Expressed Homeobox (HHEX) interaction partners

  1. hhex, nk2.1a, and pax2.1 regulate thyroid growth and differentiation downstream of Nodal-dependent transcription factors.

  2. Data suggest that zebrafish hhex appears to be activated by Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) in the dorsal yolk syncytial layer, where bozozok acts in a permissive way to limit repression of hhex by Vega1 and Vega2.

Hematopoietically Expressed Homeobox (HHEX) Antigen Profile

Protein Summary

This gene encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation.

Gene names and symbols associated with HHEX

  • Homeobox protein PRH (Bm1_31285) antibody
  • Homeobox protein PRH (hhex) antibody
  • hematopoietically expressed homeobox (hhex) antibody
  • hematopoietically expressed homeobox (HHEX) antibody
  • hematopoietically expressed homeobox (Hex1) antibody
  • hematopoietically expressed homeobox (Hhex) antibody
  • HEX antibody
  • Hex1 antibody
  • HHEX antibody
  • hhex-A antibody
  • Hhex-rs2 antibody
  • HMPH antibody
  • HOX11L-PEN antibody
  • Prh antibody
  • Prhx antibody
  • PROBOX antibody
  • tHex antibody
  • XHex antibody

Protein level used designations for HHEX

Homeobox protein PRH , hematopoietically-expressed homeobox protein hhex , homeobox protein hex , homeodomain transcription factor , hematopoietically expressed homeobox , hematopoietically-expressed homeobox protein HHEX , homeobox protein HEX , homeobox protein PRH , homeobox, hematopoietically expressed , proline-rich homeodomain-containing transcription factor , hematopoietically expressed homeobox protein , hematopoietically expressed homeobox, related sequence 2 , hematopoietically-expressed homeobox protein Hhex , mHex

GENE ID SPECIES
6101149 Brugia malayi
100305190 Oncorhynchus mykiss
395060 Xenopus (Silurana) tropicalis
450612 Pan troglodytes
7235725 Branchiostoma floridae
100303530 Saccoglossus kowalevskii
373590 Xenopus laevis
3087 Homo sapiens
608175 Canis lupus familiaris
397232 Sus scrofa
539542 Bos taurus
15242 Mus musculus
79237 Rattus norvegicus
396182 Gallus gallus
30098 Danio rerio
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