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Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Additionally we are shipping Heme Oxygenase (Decycling) 1 Kits (46) and Heme Oxygenase (Decycling) 1 Proteins (36) and many more products for this protein.
Showing 10 out of 354 products:
Cow (Bovine) Monoclonal HMOX1 Primary Antibody for ICC, IF - ABIN361697
Brydun, Watari, Yamamoto, Okuhara, Teragawa, Kono, Chayama, Oshima, Ozono: Reduced expression of heme oxygenase-1 in patients with coronary atherosclerosis. in Hypertension research : official journal of the Japanese Society of Hypertension 2007
Show all 9 references for ABIN361697
Dog (Canine) Polyclonal HMOX1 Primary Antibody for ICC, IF - ABIN361674
Froh, Conzelmann, Walbrun, Netter, Wiest, Wheeler, Lehnert, Uesugi, Scholmerich, Thurman: Heme oxygenase-1 overexpression increases liver injury after bile duct ligation in rats. in World journal of gastroenterology : WJG 2007
Show all 7 references for ABIN361674
Mouse (Murine) Polyclonal HMOX1 Primary Antibody for WB - ABIN2482092
Elbirt, Bonkovsky: Heme oxygenase: recent advances in understanding its regulation and role. in Proceedings of the Association of American Physicians 1999
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Human Monoclonal HMOX1 Primary Antibody for IF, IP - ABIN968129
Foresti, Clark, Green, Motterlini: Thiol compounds interact with nitric oxide in regulating heme oxygenase-1 induction in endothelial cells. Involvement of superoxide and peroxynitrite anions. in The Journal of biological chemistry 1997
Show all 4 references for ABIN968129
Hamster Polyclonal HMOX1 Primary Antibody for IP, IHC - ABIN223113
Song, Shih, Chan, Zhang: Suppression of annexin A11 in ovarian cancer: implications in chemoresistance. in Neoplasia (New York, N.Y.) 2009
Show all 4 references for ABIN223113
Human Polyclonal HMOX1 Primary Antibody for EIA, FACS - ABIN952705
Wu, Chiou, Chen, Wang, Hsieh, Lien, Lee, Chen: GT-repeat polymorphism in the heme oxygenase-1 gene promoter is associated with cardiovascular mortality risk in an arsenic-exposed population in northeastern Taiwan. in Toxicology and applied pharmacology 2010
Show all 2 references for ABIN952705
Human Polyclonal HMOX1 Primary Antibody for WB - ABIN2782158
Hausmann, Paul, Kellermeier, Frey, Schölmerich, Falk, Menzel, Fried, Herfarth, Rogler: (GT)N dinucleotide repeat polymorphism of haem oxygenase-1 promotor region is not associated with inflammatory bowel disease risk or disease course. in Clinical and experimental immunology 2008
study evaluated the time-course of HO-1 and catalase (show CAT Antibodies) gene expressions in nodules and roots of soybean plants subjected to cadmium treatment
Data suggest expression of hsp32 is up-regulated in kidney epithelial cells upon in vitro exposure to heavy metal water pollutants (Cd, As) or proteasomal inhibitors (MG132, withaferin A, celastrol); heat shock may be synergistic factor.
Bach1 (show BACH1 Antibodies) regulates the liver specificity and transience of the Nrf2a (show NFE2L2 Antibodies)-dependent induction of hmox1a and that heme mediates this regulation through Bach1 (show BACH1 Antibodies) inhibition based on its level in each tissue.
Data indicate that Heme oxygenase 1 (HY1) functioned negatively and acted upstream of ABSCISIC ACID-INSENSITIVE4 (ABI4) in drought signaling.
HY1 confers cadmium tolerance by decreasing nitric oxide production and improving iron homeostasis.
Data indicate that AtHO1 (HY1; heme oxygenase-1)-overexpressing plants generated more NO, whereas knock-down of AtHO1 expression reduced the level of nitric oxide (NO) in plants.
HY1 mutant exhibited progressive salt hypersensitivity.
Disrupting the binding of the AtHBP5 to haem oxygenase 1 (HY1) leads to oxidative stress.
Mutation of HY1 causes UV-C hypersensitivity by impairing carotenoid and flavonoid biosynthesis and the down-regulation of antioxidant defence.
HY1 and HY5 additively regulate the expression of light regulated genes and accumulation of chlorophyll and anthocyanin during early seedling development.
HY1 (Heme oxygenase 1) plays an important role in salt acclimation.
all members of the HO1 subfamily (HY1, HO3 and HO4) are active monomeric HOs and can convert haem to BV IXalpha using spinach Fd (ferredoxin) as an electron donor
HO2 (show HMOX2 Antibodies) has an activity high enough to substitute for HO1 under aerobic conditions.
Down regulated miR (show MLXIP Antibodies)-196a2 may be involved in intestinal Behcet's disease pathogenesis by targeting Bach1 (show BACH1 Antibodies)/ho-1.
The present study suggests a weak association between HMOX2 (show HMOX2 Antibodies) rs1051308 polymorphism and the risk to develop multiple sclerosis (MS) in Spanish Caucasian men and a trend towards association between the HMOX1 rs2071746A and MS risk.
The data demonstrate the important role of HO-1 in the pathogenesis and tumorigenesis of Kaposi's Sarcoma-associated Herpesvirus-infected endothelial cells, the underlying regulatory mechanisms for HO-1 expression and targeting HO-1 may represent a promising therapeutic strategy against Kaposi's Sarcoma-associated Herpesvirus-related malignancies.
Study identified that esophageal squamous cell carcinoma (ESCC) tumors frequently expressed HO-1 and showed that blocking its expression in ESCC cell lines resulted in decreased cellular proliferation, increased reactive oxygen species levels, and increased cellular apoptosis.
Our findings establish the HO-1/CO system and redox regulation of mitochondrial biogenesis as essential factors in ES cell differentiation as well as in the subsequent maturation of these cells into functional cardiac cells.
the inhibition of HO-1 or the knockdown of Nrf-2 significantly enhanced cisplatin's anticancer effects on Hep-2 cells.
These findings suggest that HO-1 might play a pivotal role in IDD (show COL9A3 Antibodies), and that manipulating HO-1 expression might mitigate the impairment of ECM (show MMRN1 Antibodies) metabolism in NP, thus potentially offering a novel therapeutic approach to the treatment of IDD (show COL9A3 Antibodies).
Infants carrying short alleles (< 22 (GT)n repeats) in the HMOX1 gene promoter region appear to be at a higher risk for developing neonatal hyperbilirubinemia.
Cardamonin exposure and selenium availability regulate expression of HO-1, GPX2 (show GPX2 Antibodies) and TrxR1 (show TXNRD1 Antibodies) in human intestinal cells.
HO-1, which is involved in the development of chemoresistance in leukemia cells by regulating autophagy, may be a novel target for improving leukemia therapy.
findings collectively suggest that miR (show MYLIP Antibodies)-506 acts as a tumor suppressor via regulation of ROCK1 (show ROCK1 Antibodies) expression and may thus be a promising therapeutic target for HCC (show FAM126A Antibodies)
Exogenous administration of CO exacerbated allergic symptoms, resulting in higher levels of both CO and heme oxygenase-1 expression, and a further reduction in H2S levels and CSE expression.
Down-regulation of HO-1 is associated with pulmonary arterial hypertension and right ventricular failure.
The study revealed the involvement of HO-1 in classical swine fever virus proliferation.
The protective properties of flavonoids, such as EGCG, against endothelial inflammation may be regulated in part though induction of HO-1 and subsequent activator protein-1 signaling.
Glutamate (show GRIN2C Antibodies) regulates Ca2 (show CA2 Antibodies)+ signals in smooth muscle cells of newborn piglet brain slice arterioles through astrocyte- and heme oxygenase-dependent mechanisms.
obalt protoporphyrin prevents postictal cerebral vascular dysfunction by upregulating HO-1.
Data demonstrate that lipopolysaccharides evoke a heat shock response, with an increase heat shock proteins 70 and Hsp32) and of VEGF (show VEGFA Antibodies), a specific endothelial cell growth factor (show FGF1 Antibodies).
Interaction of soluble factors in plasma possibly generated during PICSO are not responsible for upregulation of HO-1 and VEGF mRNA.
the data were consistent with HO-1 acting as an anti-viral factor and these findings suggested that induction of HO-1 may be a useful prevention and treatment strategy against BVDV infection.
These findings suggest that bronchiolar epithelial cells and macrophages up-regulate Nrf2 (show NFE2L2 Antibodies) expression early in the course of infection, which results in increased expression of HO-1 within these cells.
investigation of molecular mechanisms of microvascular complications in diabetes/hyperglycemia: regulation of HO-1 gene expression in aortic endothelial cells by advanced glycation end products
Sickle blood increases endothelial heme oxygenase activity.
data provide evidence for the involvement of the thioredoxin/thioredoxin (show TXN Antibodies) receptor system, in the regulation of haem oxygenase-1 expression in aortic endothelial cells during pro-oxidant challenge
Heme oxygenase-1 induction modulates hypoxic pulmonary vasoconstriction through upregulation of ecSOD/SOD3 (show SOD3 Antibodies).
HO-1 was upregulated in spinal cord microglial cells after spinal nerve injury.
tussilagonone exerts its anti-inflammatory effects via upregulation of HO-1 expression
Demonstrate role for heme oxygenase 1 inhibitor zinc protoporphyrin in the treatment of neonatal hyperbilirubinemia caused by hemolytic diseases.
Our results suggest a protective function of HO-1 induction in psoriasis. The protective effect of HO-1 may be attributed to its effect on the Stat3 signaling pathway via increased SHP-1 expression.
LPS (show TLR4 Antibodies)-stimulated TNF-alpha (show TNF Antibodies) was significantly decreased, whereas IRG1 and A20 (show TNFAIP3 Antibodies) were increased by CORM-2 application and HO-1 induction, which in turn were abrogated by ZnPP.
4,7-Dimethoxy-5-methyl-1,3-benzodioxole from Antrodia camphorata increased hemoxygenase-1 expression in macrophages
These results suggest that RvD1 could effectively prevent CCl4 (show CCL4 Antibodies)-induced liver injury by inhibition of oxidative stress and inflammation, and the underlying mechanism may be related to up-regulation of HO-1.
Our findings demonstrate that DEE and a fraction derived from this extract exerts anti-inflammatory effects through Nrf2dependent HO-1 expression
Tissue HO-1 exerts anti-inflammatory effects on lipopolysaccharide-induced pulmonary inflammation.
Ligustrazine injection possesses notable protective effects on ischemia/reperfusion injury in rabbits by increasing the expression of HO-1 in lung.
Results add new evidence for the importance of HO-1 in the genesis and development of atherosclerosis and provide several possible mechanisms underlying the anti-atherosclerosis effects of HO-1
the effect of HO-1 on the progression and stabilization of vulnerable plaques and the possible mechanism
Heme-L-lysinate could attenuate atherosclerotic progression through upregulating HO-1 and HSP70 (show HSP70 Antibodies) expression and increasing CO production.
These results suggest that HO-1 is important in limiting in-stent stenosis and can be regarded as a new therapeutic target.
Statins showed anti-atherosclerotic effects mediated by HO-1/eNOS (show NOS3 Antibodies), restoring the [NO]/[ONOO(-)] imbalance and reducing lipid peroxidation.
HO-1/CO system was activated and may be one of the protective signal pathway during pulmonary ischemia-reperfusion injury in rabbits.
HO-1 contributes to vascular repair by increasing circulating endothelial progenitor cells (EPCs) derived from the bone marrow.
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.
heme oxygenase (decycling) 1
, heme oxygenase 1
, heme oxygenase
, Heme oxygenase
, heat shock protein, 32-kD
, heat shock protein 32
, heme oxygenase (decyclizing) 1
, P32 protein
, heme oxygenase-1