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Hemochromatosis (HFE) ELISA Kits

The protein encoded by HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). Additionally we are shipping HFE Antibodies (70) and HFE Proteins (15) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
HFE 3077 Q30201
Anti-Rat HFE HFE 29199 O35799
Anti-Mouse HFE HFE 15216 P70387
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Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 19.5 pg/ml 78-5000 pg/mL 96 Tests Log in to see 11 to 13 Days

More ELISA Kits for HFE Interaction Partners

Human Hemochromatosis (HFE) interaction partners

  1. Total iron binding capacity was strongly associated with variants in and near the TF gene, and with variants in HFE gene in premenopausal women of European descent.

  2. HFE gene expression level of iron deficiency anemia patients was significantly higher than other groups.

  3. The HFE- and non-HFE hemochromatosis syndromes represent the paradigms of genetic iron overload.

  4. results indicate the association between the C282Y/Q283P compound heterozygous genotype in trans and the development of iron overload; this is the second case report on the HFE Q283P mutation in hemochromtosis

  5. study provides evidence that the complex allele HFE-c.[187C>G;340+4T>C] has a role, as genetic predisposition factor, on iron overload in the Sao Miguel population

  6. Its polymorphism does not influence ALS phenotype and survival.

  7. iron dysregulation associated with HFE allelic variants may play an important role in increasing susceptibility to environmental exposures, leading to recurring injury and fibrosis in idiopathic pulmonary fibrosis

  8. this review describes the pertinence of HFE and HFE to mechanisms of iron homeostasis, the origin and fixation of HFE polymorphisms in European and other populations, and the genetic and biochemical basis of HFE hemochromatosis and iron overload. [review]

  9. this analysis provided strong evidence that the HFE H63D polymorphism may play a critical role in the increased aggressiveness of hepatocellular carcinoma and pancreatic cancer.

  10. haplotype analysis of common HFE mutations in the Portuguese population, is reported.

Mouse (Murine) Hemochromatosis (HFE) interaction partners

  1. unlike homozygous Hfe deletion, heterozygous gene deletion disrupted glucose homeostasis but did not affect lipid metabolism or liver injury.

  2. Single Hjv (show HFE2 ELISA Kits)(-)/(-) and double Hfe(-)/(-)Hjv (show HFE2 ELISA Kits)(-)/(-) mice exhibit comparable iron overload. Hfe and Hjv (show HFE2 ELISA Kits) regulate hepcidin (show HAMP ELISA Kits) via the same pathway.

  3. Results show that HFE requires HJV (show HFE2 ELISA Kits) to activate downstream signal transduction pathways for hepcidin (show HAMP ELISA Kits) regulation.

  4. Alterations in cholesterol metabolism associated with expression of H63D-HFE may contribute to the development of AD.

  5. results provide evidence that HFE induces hepcidin (show HAMP ELISA Kits) expression via the BMP pathway: HFE interacts with ALK3 (show BMPR1A ELISA Kits) to stabilize ALK3 (show BMPR1A ELISA Kits) protein and increase ALK3 (show BMPR1A ELISA Kits) expression at the cell surface.

  6. These results support in vivo studies which suggest that Hfe and Tfr2 (show TFR2 ELISA Kits) can independently regulate hepcidin (show HAMP ELISA Kits).

  7. A mutation in the HFE gene is associated with altered brain iron profiles and increased oxidative stress in mice.

  8. Hfe-knockout mice did not have higher brain iron levels than wildtype controls.

  9. Hfe(-/-) retinal pigment epithelial cells exhibited slower senescence rate and higher survivin (show BIRC5 ELISA Kits) expression than wild type cells. Hfe(-/-) cells migrated faster and showed greater glucose uptake and increased expression of GLUTs.

  10. Findings suggest a novel role for Hfe and/or imbalanced iron homeostasis in the regulation of the inflammatory response in the lung and hereditary hemochromatosis.

HFE Antigen Profile

Antigen Summary

The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.

Gene names and symbols associated with Hemochromatosis (HFE) ELISA Kits

  • hemochromatosis (HFE) antibody
  • hemochromatosis (Hfe) antibody
  • HFE1 antibody
  • HH antibody
  • HLA-H antibody
  • MR2 antibody
  • MVCD7 antibody
  • TFQTL2 antibody

Protein level used designations for Hemochromatosis (HFE) ELISA Kits

MHC class I-like protein HFE , hereditary hemochromatosis protein , hereditary hemochromatosis protein HLA-H , high Fe , RT1-CAFE , hereditary hemochromatosis protein homolog , hemochromatosis protein

3077 Homo sapiens
497622 Bos taurus
29199 Rattus norvegicus
15216 Mus musculus
462489 Pan troglodytes
100688951 Canis lupus familiaris
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