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anti-Hemoglobin, gamma A (HBG1) Antibodies

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Additionally we are shipping HBG1 Proteins (12) and HBG1 Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HBG1 94164  
HBG1 3047 P69891
HBG1    
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Top anti-HBG1 Antibodies at antibodies-online.com

Showing 10 out of 39 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB HBG1 Antibody (Center) (ABIN657619) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the HBG1 antibody detected the HBG1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (33.04 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Biotin WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged HBG1 is 3 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit HRP WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit APC WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit Biotin WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit Alkaline Phosphatase (AP) WB   200 μL Log in to see 16 Days
$710.29
Details

HBG1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)


Human ,
,
,
, , , , ,
Mouse (Murine)


Top referenced anti-HBG1 Antibodies

  1. Human Polyclonal HBG1 Primary Antibody for WB - ABIN657619 : Zhou, Liu, Sun, Pawlik, Townes: KLF1 regulates BCL11A expression and gamma- to beta-globin gene switching. in Nature genetics 2010 (PubMed)

  2. Human Polyclonal HBG1 Primary Antibody for ELISA, WB - ABIN561232 : Lee, Kim, Byrnes, de Vasconcellos, Noh, Rabel, Meier, Miller: A synthetic model of human beta-thalassemia erythropoiesis using CD34+ cells from healthy adult donors. in PLoS ONE 2013 (PubMed)

More Antibodies against HBG1 Interaction Partners

Human Hemoglobin, gamma A (HBG1) interaction partners

  1. These data confirm the regulatory role of the HBG1: g.-225_-222 region that exerts its effect under conditions of erythropoietic stress characteristic for beta-thal patients.

  2. results suggest that KLF1 directly regulates the beta-globin gene, but probably has less direct impact on expression of the gamma-globin gene in fetal erythroblasts

  3. Data show that the ancestral allele C at rs2855126, located upstream of gamma-globin (HBG1) is associated with increased serum uric acid levels.

  4. analysis of a point mutation that increases fetal globin expression through de novo recruitment of the activator TAL1 to promote chromatin looping of distal enhancers to the modified gamma-globin promoter

  5. a successful induction of gamma-globin includes a reduction in BCL11A (show BCL11A Antibodies), KLF1 (show KLF1 Antibodies) and TAL1 (show TAL1 Antibodies) expression.

  6. This report we discusses the molecular characteristics and diagnostic criteria of a new (A)gamma chain variant that was detected during newborn screening and named Hb F-Sykesville MD [(A)gamma113(G15 (show RBM5 Antibodies))Val --> Ile; HBG1: c.340G>A].

  7. Results indicate that compound II induces the gamma globin gene in hydroxyurea (HU)-resistant primary adult erythroid cells and suggest potenetial therapy for sickle cell disease (SCD (show SCD Antibodies)) and severe beta-thalassemias.

  8. Inactivation of HDAC1 or HDAC2 induces gamma-globin expression without altering cell cycle or proliferation.

  9. Findings indicate that both antisickling beta-globin and gamma-globin lentiviral vectors demonstrate efficient gene transfer into sickle cells.

  10. Data indicate that hydroxyurea (HU) induces SAR1 (show IQGAP1 Antibodies) protein expression, which in turn activates gamma-globin expression, predominantly through the Gialpha/JNK (show MAPK8 Antibodies)/Jun (show JUN Antibodies) pathway.

HBG1 Antigen Profile

Protein Summary

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Gene names and symbols associated with HBG1

  • hemoglobin subunit gamma-1-like (LOC100438895) antibody
  • hemoglobin, gamma A (Hbg1) antibody
  • hemoglobin, gamma A (HBG1) antibody
  • hemoglobin, gamma G (HBG2) antibody
  • Hbb-y antibody
  • Hbe1 antibody
  • HBG1 antibody
  • HBG2 antibody
  • HBGA antibody
  • HBGR antibody
  • HSGGL1 antibody

Protein level used designations for HBG1

epsilon 3 globin , hemoglobin Y beta-like embryonic chain , hemoglobin Y, beta-like embryonic chain , hemoglobin, epsilon 1 , hemoglobin, gamma A , A-gamma globin , gamma A hemoglobin , gamma globin , gamma-1-globin , hb F Agamma , hemoglobin gamma-1 chain , hemoglobin gamma-a chain , hemoglobin subunit gamma-1 , hemoglobin, gamma, regulator of , epsilon-globin , hemoglobin, gamma G

GENE ID SPECIES
100438895 Pongo abelii
94164 Rattus norvegicus
100137314 Papio anubis
3047 Homo sapiens
450979 Pan troglodytes
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