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Hemoglobin, gamma A Proteins (HBG1)

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Additionally we are shipping HBG1 Antibodies (39) and HBG1 Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat HBG1 HBG1 94164  
HBG1 3047 P69891
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Top HBG1 Proteins at

Showing 9 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
Yeast Primate His tag   1 mg Log in to see 56 to 66 Days
Yeast Pongo pygmaeus His tag   1 mg Log in to see 56 to 66 Days
Yeast Pan troglodytes His tag   1 mg Log in to see 56 to 66 Days
Yeast Pan paniscus His tag   1 mg Log in to see 56 to 66 Days
Yeast REACT_Titi monkey His tag   1 mg Log in to see 56 to 66 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

HBG1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
Primate (Cebus)

More Proteins for Hemoglobin, gamma A (HBG1) Interaction Partners

Human Hemoglobin, gamma A (HBG1) interaction partners

  1. results suggest that KLF1 directly regulates the beta-globin gene, but probably has less direct impact on expression of the gamma-globin gene in fetal erythroblasts

  2. Data show that the ancestral allele C at rs2855126, located upstream of gamma-globin (HBG1) is associated with increased serum uric acid levels.

  3. analysis of a point mutation that increases fetal globin expression through de novo recruitment of the activator TAL1 to promote chromatin looping of distal enhancers to the modified gamma-globin promoter

  4. a successful induction of gamma-globin includes a reduction in BCL11A (show BCL11A Proteins), KLF1 (show KLF1 Proteins) and TAL1 (show TAL1 Proteins) expression.

  5. This report we discusses the molecular characteristics and diagnostic criteria of a new (A)gamma chain variant that was detected during newborn screening and named Hb F-Sykesville MD [(A)gamma113(G15 (show RBM5 Proteins))Val --> Ile; HBG1: c.340G>A].

  6. Results indicate that compound II induces the gamma globin gene in hydroxyurea (HU)-resistant primary adult erythroid cells and suggest potenetial therapy for sickle cell disease (SCD (show SCD Proteins)) and severe beta-thalassemias.

  7. Inactivation of HDAC1 or HDAC2 induces gamma-globin expression without altering cell cycle or proliferation.

  8. Findings indicate that both antisickling beta-globin and gamma-globin lentiviral vectors demonstrate efficient gene transfer into sickle cells.

  9. Data indicate that hydroxyurea (HU) induces SAR1 protein expression, which in turn activates gamma-globin expression, predominantly through the Gialpha/JNK (show MAPK8 Proteins)/Jun (show JUN Proteins) pathway.

  10. There is synergism between developmental stage-specific recruitments of the ATF2 protein complex and expression of gamma-globin during erythropoiesis.

HBG1 Protein Profile

Protein Summary

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Gene names and symbols associated with Hemoglobin, gamma A Proteins (HBG1)

  • hemoglobin subunit gamma-1-like (LOC100438895)
  • hemoglobin, gamma A (Hbg1)
  • hemoglobin, gamma A (HBG1)
  • hemoglobin, gamma G (HBG2)
  • Hbb-y protein
  • Hbe1 protein
  • HBG1 protein
  • HBG2 protein
  • HBGA protein
  • HBGR protein
  • HSGGL1 protein

Protein level used designations for Hemoglobin, gamma A Proteins (HBG1)

epsilon 3 globin , hemoglobin Y beta-like embryonic chain , hemoglobin Y, beta-like embryonic chain , hemoglobin, epsilon 1 , hemoglobin, gamma A , A-gamma globin , gamma A hemoglobin , gamma globin , gamma-1-globin , hb F Agamma , hemoglobin gamma-1 chain , hemoglobin gamma-a chain , hemoglobin subunit gamma-1 , hemoglobin, gamma, regulator of , epsilon-globin , hemoglobin, gamma G

100438895 Pongo abelii
94164 Rattus norvegicus
100137314 Papio anubis
3047 Homo sapiens
450979 Pan troglodytes
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