anti-Hemoglobin beta (HBB) Antibodies

The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. Additionally we are shipping Hemoglobin Subunit beta Proteins (201) and Hemoglobin Subunit beta Kits (26) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HBB 3043 P68871
HBB 24440 P02091
HBB 15129  
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Top anti-Hemoglobin Subunit beta Antibodies at antibodies-online.com

Showing 10 out of 81 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB HBB Antibody (C-term) (ABIN655504) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the HBB antibody detected the HBB protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged HBB is approximately 0.3ng/ml as a capture antibody. Western Blot detection against Immunogen (37.84 KDa) . 100 μg Log in to see 11 to 12 Days
$430.00
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to HBB on formalin-fixed paraffin-embedded human lung. [antibody concentration 3 ug/ml] Detection limit for recombinant GST tagged HBB is approximately 0.1ng/ml as a capture antibody. 100 μg Log in to see 11 to 12 Days
$430.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Rabbit Anti-Goat IgG at 1: 5000;  TMB staining Read the data in Microplate Reader by 450nm. 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (38.21 KDa) . 50 μL Log in to see 11 to 12 Days
$298.57
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 16 Days
$460.63
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Un-conjugated FACS, IHC, WB Western blot analysis of extracts of Raji cells, using HBB antibody. 100 μL Log in to see 16 Days
$323.13
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged HBB is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to HBB on formalin-fixed paraffin-embedded human lung (antibody concentration 3 µg/mL).  Detection limit for recombinant GST tagged HBB is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details

HBB Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Hemoglobin Subunit beta Antibodies

  1. Human Monoclonal Hemoglobin Subunit beta Primary Antibody for ELISA, WB - ABIN561229 : Xie, Ren, Zhang, Guo, Wang, Wang, Lin, Gong, Li, Huang, Zeng, Zeng: Restoration of the balanced alpha/beta-globin gene expression in beta654-thalassemia mice using combined RNAi and antisense RNA approach. in Human molecular genetics 2007 (PubMed)
    Show all 2 references for 561229

  2. Human Monoclonal Hemoglobin Subunit beta Primary Antibody for IHC (p), ELISA - ABIN561230 : Ishikawa, Ohlmeier, Salmenkivi, Myllärniemi, Rahman, Mazur, Kinnula: Hemoglobin ? and ? are ubiquitous in the human lung, decline in idiopathic pulmonary fibrosis but not in COPD. in Respiratory research 2010 (PubMed)
    Show all 2 references for 561230

  3. Human Polyclonal Hemoglobin Subunit beta Primary Antibody for ELISA, WB - ABIN561228 : Martins, Rino, Carvalho, Carvalho, Yoshida, Klose, de Almeida, Carmo-Fonseca: Spliceosome assembly is coupled to RNA polymerase II dynamics at the 3' end of human genes. in Nature structural & molecular biology 2011 (PubMed)

More Antibodies against Hemoglobin Subunit beta Interaction Partners

Orang-Utan Hemoglobin beta (HBB) interaction partners

  1. Pan (show SUPT6H Antibodies) troglodytes and Pongo pygmaeus were screened for mutations in the beta-globin gene (exons 1, 2, and 3) for suspected thalassemia.

Cow (Bovine) Hemoglobin beta (HBB) interaction partners

  1. Data indicate that on incubating hemoglobin with glyoxal for 0-20 days, advanced glycation end products (AGEs) were detected on day 20.

Horse (Equine) Hemoglobin beta (HBB) interaction partners

Pig (Porcine) Hemoglobin beta (HBB) interaction partners

  1. In this study, hemoglobin subunit beta was identified as a classical swine fever virus capsid protein-binding protein by glutathione S-transferase (show GSTa2 Antibodies) pulldown and subsequent mass spectrometry analysis of PK-15 cells.

Human Hemoglobin beta (HBB) interaction partners

  1. Five different beta-globin haplotypes were linked to sickle hemoglobin alleles in Mazandaran province.

  2. 2 cases of Polish patients with hereditary hemolytic anemia suspected of thalassemia were studied; identified 2 different frameshift mutations positioned in the third exon of HBB; results show a lack of natural stop codon due to the frameshift in exon 3 of beta-globin gene causes rapid degradation of its mRNA and indicate existence of novel surveillance pathway

  3. Our work suggested a novel function for HBB as a theranostic molecule: an innate antimetastasis factor with potential utility as an anticancer drug and a biomarker signaling the presence of clinically undetectable metastasis

  4. we concluded that this novel beta-globin gene mutation was associated with the mild phenotype of beta-thal.

  5. We first report a novel beta chain variant, Hb Heze [beta144(HC1)Lys (show LYZ Antibodies)-->Arg; HBB: c.434A>G], in a Chinese family. Heterozygous inheritance of the mutation results in a mild beta-thalassemia (beta-thal) phenotype, whereas compound heterozygosity of Hb Heze with beta(0)-thal appears as the cause of beta-thal intermedia (beta-TI) in our case.

  6. the Fe-His bond of the beta subunits at alkaline pH causes a substantial increase in the change in global structure upon binding of CO to the beta subunit (show POLG Antibodies)

  7. We screened for b-thalassemia-causing mutations by direct sequencing in different districts of West Bengal. Mutation detection was done using Sanger sequencing of the HBB gene. Results: A total of 14 different mutations were observed, including rare mutations IVS1-130(G>C), IVS1-129(A>C), -90(T>C), CD16 (show CD16 Antibodies)(-C), -30(T>C), CD15 (show FUT4 Antibodies)(-T), and a novel mutation CD53 (show CD53 Antibodies)(C>T).

  8. A report on the frequency and spectrum of beta globin gene mutations in thalassemia patients in a Pakistani population.

  9. Data indicate that binding of hemoblobin (Hb) to glycoprotein1balpha (GP1balpha) induced platelet activation plays a crucial role in thrombus formation on immobilized von Willebrand factor (VWF (show VWF Antibodies)) or type I collagen under shear stresses.

  10. Data suggest that coagulation factor IX (hFIX) minigene containing beta-globin (hBG) introns could represent a particular interest in stem cell-based gene therapy of hemophilias.

Chimpanzee Hemoglobin beta (HBB) interaction partners

  1. Pan (show SUPT6H Antibodies) troglodytes and Pongo pygmaeus were screened for mutations in the beta-globin gene (exons 1, 2, and 3) for suspected thalassemia.

  2. We found no evidence of the major deleterious mutations at HBB in chimpanzees that confer resistance to malaria caused by Plasmodium falciparum nor evidence of long-term balancing selection at these loci.

Mouse (Murine) Hemoglobin beta (HBB) interaction partners

  1. results revealed iron deficiency induced expression changes in two genes which have never before been implicated in an iron-dopamine pathway, Cxcl12 and hemoglobin, beta adult chain

  2. Dynamic changes in chromatin structure of the beta-globin locus, were examined.

  3. GATA1 (show GATA1 Antibodies)-HS2 (show SPTB Antibodies) enhancer allows persistent and position-independent expression of a beta (show SUCLA2 Antibodies)-globin transgene

  4. The limiting effect on RNA levels occurs after beta-globin genes associate with transcription factories, at which time hypersensitivity sites contribute to the RNA arising from each burst of transcription by stimulating transcriptional elongation.

  5. cerebral microvasculature is rendered vulnerable to thrombus formation in beta(s) mice via a neutrophil-dependent mechanism that is associated with an increased formation of and enhanced platelet sensitivity to thrombin (show F2 Antibodies)

  6. Ldb1 (show LDB1 Antibodies) stabilizes its erythroid complex partners on beta-globin chromatin, even though it is not one of the DNA-binding components. In addition, Ldb1 (show LDB1 Antibodies) is necessary for enrichment of key transcriptional components in the locus.

  7. MLL2 (show MLL4 Antibodies) complex associates with the hematopoietic activator NF-E2 (show NFE2 Antibodies) in erythroid cells and is important for H3K4 trimethylation and maximal levels of transcription at the beta-globin locus.

  8. Bach1 repression of ferritin and thioredoxin reductase1 is heme-sensitive in cells and in vitro and coordinates expression with heme oxygenase1, beta-globin, and NADP(H) quinone (oxido) reductase1.

  9. The acetylation of EKLF (show KLF1 Antibodies) plays a role in its ability to alter the beta-like globin locus chromatin structure and activate transcription of the adult beta-globin gene.

Hemoglobin Subunit beta (HBB) Antigen Profile

Protein Summary

The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Gene names and symbols associated with anti-Hemoglobin beta (HBB) Antibodies

  • hemoglobin, beta (HBB) antibody
  • hemoglobin, gamma G (HBG2) antibody
  • hemoglobin, epsilon 1 (HBE1) antibody
  • hemoglobin, beta (HBB2) antibody
  • hemoglobin, beta (HBE) antibody
  • hemoglobin beta (HBB) antibody
  • hemoglobin subunit beta-like (LOC100720944) antibody
  • hemoglobin subunit beta-like (LOC480784) antibody
  • hemoglobin, beta (Hbb) antibody
  • hemoglobin, beta adult major chain (Hbb-b1) antibody
  • hemoglobin subunit beta-like (LOC100438527) antibody
  • beta globin (LOC100136576) antibody
  • hemoglobin beta chain complex (Hbb) antibody
  • keratin 123 pseudogene (KRT123P) antibody
  • AA409645 antibody
  • beta-globin antibody
  • beta1 antibody
  • CD113t-C antibody
  • hbb antibody
  • Hbb1 antibody
  • HBBA antibody
  • HBBB antibody
  • Hbbt1 antibody
  • Hbbt2 antibody
  • HBD antibody
  • HBE1 antibody
  • HBG1 antibody
  • HBG2 antibody
  • KRTHBP2 antibody
  • MommeD7 antibody

Protein level used designations for anti-Hemoglobin beta (HBB) Antibodies

hemoglobin, beta , beta-globin , hemoglobin beta chain , hemoglobin subunit beta , beta-A globin , hemoglobin, delta , hemoglobin, epsilon 1 , epsilon globin , beta-H globin , hemoglobin, gamma A , beta globin , beta-1/2-globin , hemoglobin beta-1/2 chain , hemoglobin subunit beta-1/2 , epsilon-globin , hemoglobin epsilon chain , hemoglobin subunit epsilon , hemoglobin, gamma G , Beta-globin , Hemoglobin beta chain , globin, beta , hemoglobin beta , beta globin chain , III beta-1 globin , III beta-2 globin , beta-1-globin , hemoglobin beta chain complex , hemoglobin beta chain, major-form , hemoglobin beta-1 chain , hemoglobin subunit beta-1 , beta maj , beta major globin

GENE ID SPECIES
100137310 Papio anubis
450978 Pan troglodytes
396485 Gallus gallus
428114 Gallus gallus
100009084 Oryctolagus cuniculus
280813 Bos taurus
428115 Gallus gallus
407066 Sus scrofa
100049064 Ovis aries
100054109 Equus caballus
100499573 Ailuropoda melanoleuca
100720944 Cavia porcellus
3043 Homo sapiens
480784 Canis lupus familiaris
715559 Macaca mulatta
24440 Rattus norvegicus
15129 Mus musculus
100438527 Pongo abelii
100136576 Salmo salar
15127 Mus musculus
85344 Homo sapiens
101098159 Felis catus
100976465 Pan paniscus
100410611 Callithrix jacchus
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