anti-Hemoglobin beta (HBB) Antibodies

The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. Additionally we are shipping Hemoglobin Subunit beta Proteins (200) and Hemoglobin Subunit beta Kits (28) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HBB 3043 P68871
HBB 24440 P02091
HBB 15127  
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Top anti-Hemoglobin Subunit beta Antibodies at antibodies-online.com

Showing 10 out of 108 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Flow Cytometric analysis of K562 cells using HBB Antibody (C-term) <em>Cat.-No</em>  (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Western blot analysis in K562 cell line lysates (35ug/lane) using HBB Antibody (C-term) <em>Cat.-No</em> AP52007PU-N. This demonstrates the HBB antibody detected the HBB protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB HBB Antibody (C-term) (ABIN655504) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the HBB antibody detected the HBB protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged HBB is approximately 0.3ng/ml as a capture antibody. Western Blot detection against Immunogen (37.84 KDa) . 100 μg Log in to see 11 to 12 Days
$430.00
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to HBB on formalin-fixed paraffin-embedded human lung. [antibody concentration 3 ug/ml] Detection limit for recombinant GST tagged HBB is approximately 0.1ng/ml as a capture antibody. 100 μg Log in to see 11 to 12 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (38.21 KDa) . 50 μL Log in to see 11 to 12 Days
$298.57
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 16 Days
$460.63
Details
Mouse Rabbit Un-conjugated ICC, IHC, IP, WB 100 μg Log in to see 15 to 18 Days
$360.00
Details
Human Rabbit Un-conjugated FACS, IHC, WB Western blot analysis of extracts of Raji cells, using HBB antibody. 100 μL Log in to see 16 Days
$323.13
Details
Sheep Mouse Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 15 to 18 Days
$329.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Rabbit Anti-Goat IgG at 1: 5000;  TMB staining Read the data in Microplate Reader by 450nm. 100 μL Log in to see 3 to 7 Days
$295.90
Details

HBB Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Hemoglobin Subunit beta Antibodies

  1. Human Monoclonal Hemoglobin Subunit beta Primary Antibody for ELISA, WB - ABIN561229 : Xie, Ren, Zhang, Guo, Wang, Wang, Lin, Gong, Li, Huang, Zeng, Zeng: Restoration of the balanced alpha/beta-globin gene expression in beta654-thalassemia mice using combined RNAi and antisense RNA approach. in Human molecular genetics 2007 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal Hemoglobin Subunit beta Primary Antibody for IHC (p), ELISA - ABIN561230 : Ishikawa, Ohlmeier, Salmenkivi, Myllärniemi, Rahman, Mazur, Kinnula: Hemoglobin ? and ? are ubiquitous in the human lung, decline in idiopathic pulmonary fibrosis but not in COPD. in Respiratory research 2010 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal Hemoglobin Subunit beta Primary Antibody for ELISA, WB - ABIN561228 : Martins, Rino, Carvalho, Carvalho, Yoshida, Klose, de Almeida, Carmo-Fonseca: Spliceosome assembly is coupled to RNA polymerase II dynamics at the 3' end of human genes. in Nature structural & molecular biology 2011 (PubMed)

More Antibodies against Hemoglobin Subunit beta Interaction Partners

Chimpanzee Hemoglobin beta (HBB) interaction partners

  1. Pan (show SUPT6H Antibodies) troglodytes and Pongo pygmaeus were screened for mutations in the beta-globin gene (exons 1, 2, and 3) for suspected thalassemia.

  2. We found no evidence of the major deleterious mutations at HBB in chimpanzees that confer resistance to malaria caused by Plasmodium falciparum nor evidence of long-term balancing selection at these loci.

Cow (Bovine) Hemoglobin beta (HBB) interaction partners

  1. Data indicate that on incubating hemoglobin with glyoxal for 0-20 days, advanced glycation end products (AGEs) were detected on day 20.

Pig (Porcine) Hemoglobin beta (HBB) interaction partners

  1. In this study, hemoglobin subunit beta was identified as a classical swine fever virus capsid protein-binding protein by glutathione S-transferase (show GSTa2 Antibodies) pulldown and subsequent mass spectrometry analysis of PK-15 cells.

Horse (Equine) Hemoglobin beta (HBB) interaction partners

Human Hemoglobin beta (HBB) interaction partners

  1. In conclusion, in this work we demonstrated that HBB is expressed by breast cancer cells, its expression is correlated with tumour aggressiveness in humans and its forced overexpression enhances breast cancer cell aggressiveness in vitro and in vivo.

  2. NF-E2 (show NFE2 Antibodies), TAL1 (show TAL1 Antibodies) and KLF1 (show KLF1 Antibodies), all activators play a primary role in HSs (show GFER Antibodies) formation in the LCR

  3. Five different beta-globin haplotypes were linked to sickle hemoglobin alleles in Mazandaran province.

  4. 2 cases of Polish patients with hereditary hemolytic anemia suspected of thalassemia were studied; identified 2 different frameshift mutations positioned in the third exon of HBB; results show a lack of natural stop codon due to the frameshift in exon 3 of beta-globin gene causes rapid degradation of its mRNA and indicate existence of novel surveillance pathway

  5. Our work suggested a novel function for HBB as a theranostic molecule: an innate antimetastasis factor with potential utility as an anticancer drug and a biomarker signaling the presence of clinically undetectable metastasis

  6. we concluded that this novel beta-globin gene mutation was associated with the mild phenotype of beta-thal.

  7. We first report a novel beta chain variant, Hb Heze [beta144(HC1)Lys-->Arg; HBB: c.434A>G], in a Chinese family. Heterozygous inheritance of the mutation results in a mild beta-thalassemia (beta-thal) phenotype, whereas compound heterozygosity of Hb Heze with beta(0)-thal appears as the cause of beta-thal intermedia (beta-TI) in our case.

  8. the Fe-His bond of the beta subunits at alkaline pH causes a substantial increase in the change in global structure upon binding of CO to the beta subunit (show POLG Antibodies)

  9. We screened for b-thalassemia-causing mutations by direct sequencing in different districts of West Bengal. Mutation detection was done using Sanger sequencing of the HBB gene. Results: A total of 14 different mutations were observed, including rare mutations IVS1-130(G>C), IVS1-129(A>C), -90(T>C), CD16 (show CD16 Antibodies)(-C), -30(T>C), CD15 (show FUT4 Antibodies)(-T), and a novel mutation CD53 (show CD53 Antibodies)(C>T).

  10. A report on the frequency and spectrum of beta globin gene mutations in thalassemia patients in a Pakistani population.

Mouse (Murine) Hemoglobin beta (HBB) interaction partners

  1. Data show that mediator is recruited to the beta-globin locus by the LDB1 (show LDB1 Antibodies) complex.

  2. In hemizygous beta-globin knockout (BKO) mice, the duodenal calcium transport was lower than that in wild-type littermates, and severity was especially pronounced in female mice.

  3. The study analyzed protein-DNA interactions in the murine beta-globin gene locus.

  4. Data suggest that beta-globin promoters in general do not exert any appreciable nonlocal effects on chromatin structure.

  5. HIRA (show HIRA Antibodies) is not only critical for beta-globin expression but is also required for activation of the erythropoietic regulators EKLF (show KLF1 Antibodies) and GATA binding protein 1 (GATA1).

  6. results revealed iron deficiency induced expression changes in two genes which have never before been implicated in an iron-dopamine pathway, Cxcl12 and hemoglobin, beta adult chain

  7. Data indicate that Myb and BCL11A cooperate with DNMT1 to achieve developmental repression of embryonic and fetal beta-like human transgenic globin genes in the adult erythroid environment.

  8. Dynamic changes in chromatin structure of the beta-globin locus, were examined.

  9. GATA1 (show GATA1 Antibodies)-HS2 (show SPTB Antibodies) enhancer allows persistent and position-independent expression of a beta (show SUCLA2 Antibodies)-globin transgene

  10. The limiting effect on RNA levels occurs after beta-globin genes associate with transcription factories, at which time hypersensitivity sites contribute to the RNA arising from each burst of transcription by stimulating transcriptional elongation.

Orang-Utan Hemoglobin beta (HBB) interaction partners

  1. Pan (show SUPT6H Antibodies) troglodytes and Pongo pygmaeus were screened for mutations in the beta-globin gene (exons 1, 2, and 3) for suspected thalassemia.

Hemoglobin Subunit beta (HBB) Antigen Profile

Protein Summary

The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Gene names and symbols associated with anti-Hemoglobin beta (HBB) Antibodies

  • hemoglobin, beta (HBB) antibody
  • hemoglobin subunit beta (HBB) antibody
  • hemoglobin, beta (HBB2) antibody
  • hemoglobin subunit beta-like (HBB) antibody
  • hemoglobin subunit beta (LOC100720944) antibody
  • hemoglobin subunit beta-like (LOC480784) antibody
  • hemoglobin subunit beta (Hbb) antibody
  • beta globin (LOC100136576) antibody
  • hemoglobin beta chain complex (Hbb) antibody
  • hemoglobin subunit beta-1 (LOC101098159) antibody
  • hemoglobin subunit beta (LOC100976465) antibody
  • hemoglobin subunit beta (LOC100410611) antibody
  • hemoglobin subunit beta (LOC105468624) antibody
  • beta-globin antibody
  • CD113t-C antibody
  • hbb antibody
  • HBB1 antibody
  • HBBA antibody
  • HBBB antibody

Protein level used designations for anti-Hemoglobin beta (HBB) Antibodies

hemoglobin, beta , beta-globin , hemoglobin beta chain , hemoglobin subunit beta , beta globin , beta-1/2-globin , hemoglobin beta-1/2 chain , hemoglobin subunit beta-1/2 , Beta-globin , Hemoglobin beta chain , globin, beta , hemoglobin beta , beta globin chain , III beta-1 globin , III beta-2 globin , beta-1-globin , hemoglobin beta chain complex , hemoglobin beta chain, major-form , hemoglobin beta-1 chain , hemoglobin subunit beta-1

GENE ID SPECIES
100137310 Papio anubis
450978 Pan troglodytes
100009084 Oryctolagus cuniculus
280813 Bos taurus
407066 Sus scrofa
100049064 Ovis aries
100054109 Equus caballus
100499573 Ailuropoda melanoleuca
100720944 Cavia porcellus
3043 Homo sapiens
480784 Canis lupus familiaris
715559 Macaca mulatta
24440 Rattus norvegicus
100438527 Pongo abelii
100136576 Salmo salar
15127 Mus musculus
101098159 Felis catus
100976465 Pan paniscus
100410611 Callithrix jacchus
105468624 Macaca nemestrina
101926697 Macaca fascicularis
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