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Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. Additionally we are shipping HS3ST3B1 Kits (12) and HS3ST3B1 Antibodies (3) and many more products for this protein.
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A genome-wide high-throughput siRNA screen revealed that KIR2DL4 (show KIR2DL4 Proteins) recognition of cell-surface ligand(s) is directly regulated by heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (HS3ST3B1).
Genetic variants of HS3ST3A1 (show HS3ST3A1 Proteins) and HS3ST3B1 are associated with Plasmodium falciparum parasitaemia.
the results from this study unveiled a distinct function for 3-OST (show HS3ST1 Proteins)-3B1 as an Epithelial-mesenchymal transition inducer in cancer and provided a link between histone modification and Epithelial-mesenchymal transition modulation.
HS3ST3B1 showed potent inhibitory effect on HBV replication.
Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-O-sulfotransferase activity. The sulfotransferase domain of this enzyme is highly similar to the same domain of heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1, and these two enzymes sulfate an identical disaccharide. This gene is widely expressed, with the most abundant expression in liver and placenta.
, heparan sulfate 3-O-sulfotransferase 3B1
, heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1
, heparan sulfate glucosamine 3-O-sulfotransferase 3B1
, D-glycosaminyl 3-O-sulfotransferase-3B