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Heparan-Sulfate 6-O-Sulfotransferase 1 Proteins (HS6ST1)

The protein encoded by HS6ST1 is a member of the heparan sulfate biosynthetic enzyme family. Additionally we are shipping Heparan-Sulfate 6-O-Sulfotransferase 1 Kits (18) and Heparan-Sulfate 6-O-Sulfotransferase 1 Antibodies (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HS6ST1 50785 Q9QYK5
Rat HS6ST1 HS6ST1 316325  
HS6ST1 9394 O60243
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Top Heparan-Sulfate 6-O-Sulfotransferase 1 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cricetulus griseus His tag   1 mg Log in to see 56 to 66 Days
$3,111.17
Details

HS6ST1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , ,
, ,

More Proteins for Heparan-Sulfate 6-O-Sulfotransferase 1 (HS6ST1) Interaction Partners

Mouse (Murine) Heparan-Sulfate 6-O-Sulfotransferase 1 (HS6ST1) interaction partners

  1. Distinct expression patterns of Sulf1 (show SULF1 Proteins) and Hs6st1 spatially regulate heparan sulfate sulfation during prostate development.

  2. both HS6ST-1 and HS6ST-2 (show HS6ST2 Proteins) are involved in 6-O-sulfation of heparin and that the proper packaging and storage of tryptase (show TPSAB1 Proteins)

  3. 6OST1 is predominantly transcribed in epithelial and neural-derived tissues during development

  4. Data show that high expression of 6-O-sulfotransferase (6-OST)-1, 2, or 3 resulted in increased 6-O-sulfation of N-sulfated (show SULF1 Proteins) and N-acetylated glucosamine units, and in altered heparan sulfate domain structure.

  5. Hs2st and/or Hs6st1 expression coincides with Slit expression domains at locations where retinal ganglion cell(RGC) axons make navigation errors in Hs2st-/- and Hs6st1-/- mutants, and Hs6st1-/-RGC axons are less sensitive to Slit2 repulsion.

  6. there is a critical role for HS 6-O sulfation by Hs6st1 in postnatal processes

Human Heparan-Sulfate 6-O-Sulfotransferase 1 (HS6ST1) interaction partners

  1. HS6ST-1 and HS6ST-2 (show HS6ST2 Proteins) have roles in regulating the angiogenic program in ovarian cancer cells affecting HB-EGF (show HBEGF Proteins) signaling and subsequent expression of angiogenic cytokines by cancer cells

  2. Hs6st1 and Hs2st (show HS2ST1 Proteins) generate conditions conducive to corpus callosum development.

  3. idiopathic hypogonadotrophic hypogonadism--associated HS6ST1 mutations display reduced activity in vitro and in vivo, suggesting that HS6ST1 and the complex modifications of extracellular sugars are critical for normal development

  4. we have characterized HS6ST-2 (show HS6ST2 Proteins) and HS6ST-1 human isologues, including their chromosomal localizations,HS6STs could also transfer sulphate to N -sulphoglucosamine residues located at the non-reducing terminal of HS with high affinity.

Heparan-Sulfate 6-O-Sulfotransferase 1 (HS6ST1) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biological activities. This enzyme is a type II integral membrane protein and is responsible for 6-O-sulfation of heparan sulfate. This enzyme does not share significant sequence similarity with other known sulfotransferases. A pseudogene located on chromosome 1 has been found for this gene.

Gene names and symbols associated with HS6ST1

  • heparan sulfate 6-O-sulfotransferase 1 (Hs6st1)
  • heparan sulfate 6-O-sulfotransferase 1 (HS6ST1)
  • 6OST1 protein
  • CHS6ST-1 protein
  • HH15 protein
  • HS6ST protein
  • HS6ST-1 protein

Protein level used designations for HS6ST1

HS6ST-1 , heparan-sulfate 6-O-sulfotransferase 1 , mHS6ST-1 , heparan-sulfate 6-sulfotransferase , Heparan-sulfate 6-O-sulfotransferase 1 , heparan sulfate 6-sulfotransferase

GENE ID SPECIES
50785 Mus musculus
316325 Rattus norvegicus
9394 Homo sapiens
395141 Gallus gallus
100688113 Canis lupus familiaris
100689173 Cricetulus griseus
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