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Hepatic and Glial Cell Adhesion Molecule Proteins (HEPACAM)

The protein encoded by HEPACAM is a single-pass type I membrane protein that localizes to the cytoplasmic side of the cell membrane. Additionally we are shipping Hepatic and Glial Cell Adhesion Molecule Antibodies (43) and Hepatic and Glial Cell Adhesion Molecule Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HEPACAM 220296 Q14CZ8
HEPACAM 72927 Q640R3
HEPACAM 521015 A4FUY1
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Top Hepatic and Glial Cell Adhesion Molecule Proteins at antibodies-online.com

Showing 8 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,508.00
Details
HOST_HEK293 Human His tag   50 μg Log in to see 5 Days
$522.50
Details
HOST_Human Cells Human His tag,ECD 100 μg Log in to see 16 Days
$437.80
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

HEPACAM Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, ,
Mouse (Murine) ,
,
Cow (Bovine)

More Proteins for Hepatic and Glial Cell Adhesion Molecule (HEPACAM) Interaction Partners

Human Hepatic and Glial Cell Adhesion Molecule (HEPACAM) interaction partners

  1. Due to the ability to reactivate expression of hepaCAM and inhibit growth of bladder cancer cells, AZAC may represent an effective treatment for bladder cancer.

  2. The extracellular domain of GlialCAM is necessary for cell junction targeting and for mediating interactions with itself or with MLC1 and ClC-2 (show CLCN2 Proteins).

  3. HepaCAM may prevent the translocation of PKCepsilon (show PRKCE Proteins) from cytosolic to particulate fractions, resulting in the inhibition of 786-0 cell proliferation.

  4. GlialCAM is able to interact with all CLC (show CLC Proteins) channels tested in this study, targeting them to cell junctions and activating them by stabilizing the open configuration of the common gate

  5. Results allow classifying the effect of HEPACAM gene mutations in different subtypes and authors indicate different cellular mechanisms that lead to megalencephalic leukoencephalopathy pathogenesis.

  6. we demonstrate an evolutionary conserved role for MLC1 in regulating glial surface levels of GLIALCAM, and this interrelationship explains why patients with mutations in either gene (MLC1 or GLIALCAM) share the same clinical phenotype.

  7. High expression of hepaCAM is associated with renal carcinoma.

  8. analysis of mutations in GLIALCAM in patients with megalencephalic leukoencephalopathy with subcortical cysts [case report]

  9. results suggested that HepaCAM acted as a tumor suppressor in prostate cancer

  10. Re-activation of hepaCAM gene by 5-aza-CdR (show RUNX1T1 Proteins) can inhibit growth of cancer cells and arrest cells at G0/G1 phase

Mouse (Murine) Hepatic and Glial Cell Adhesion Molecule (HEPACAM) interaction partners

  1. we demonstrate an evolutionary conserved role for MLC1 in regulating glial surface levels of GLIALCAM, and this interrelationship explains why patients with mutations in either gene (MLC1 or GLIALCAM) share the same clinical phenotype.

  2. Data indicate that membrane protein MLC1 is crucial for proper localization of adhesion molecule (show NCAM1 Proteins) GlialCAM and chloride channel (show CLCA1 Proteins) ClC-2 (show CLCN2 Proteins), and for changing ClC-2 (show CLCN2 Proteins) currents.

  3. GlialCAM, an immunoglobulin-like cell adhesion molecule (show MCAM Proteins) is expressed in glial cells of the central nervous system.

Hepatic and Glial Cell Adhesion Molecule (HEPACAM) Protein Profile

Protein Summary

The protein encoded by this gene is a single-pass type I membrane protein that localizes to the cytoplasmic side of the cell membrane. The encoded protein acts as a homodimer and is involved in cell motility and cell-matrix interactions. The expression of this gene is downregulated or undetectable in many cancer cell lines, so this may be a tumor suppressor gene.

Gene names and symbols associated with HEPACAM

  • hepatic and glial cell adhesion molecule (HEPACAM)
  • hepatocyte cell adhesion molecule (Hepacam)
  • 2900042E01Rik protein
  • GlialCAM protein
  • Hepn1 protein
  • MLC2A protein
  • MLC2B protein

Protein level used designations for HEPACAM

hepatocyte cell adhesion molecule , protein hepaCAM

GENE ID SPECIES
100064233 Equus caballus
220296 Homo sapiens
489305 Canis lupus familiaris
521015 Bos taurus
72927 Mus musculus
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