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The protein encoded by HAVCR1 is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. Additionally we are shipping HAVCR1 Antibodies (188) and HAVCR1 Kits (81) and many more products for this protein.
Showing 10 out of 33 products:
Human HAVCR1 Protein expressed in HEK-293 Cells - ABIN2181417
Silberstein, Dveksler, Kaplan: Neutralization of hepatitis A virus (HAV) by an immunoadhesin containing the cysteine-rich region of HAV cellular receptor-1. in Journal of virology 2001
Human HAVCR1 Protein expressed in Human Cells - ABIN2003797
Gandhi, Yi, Ha, Shi, Ismail, Nathoo, Bonventre, Zhang, Gunaratnam: Accelerated receptor shedding inhibits kidney injury molecule-1 (KIM-1)-mediated efferocytosis. in American journal of physiology. Renal physiology 2014
Data suggest that T-cell immunoglobulin domain and mucin domain containing protein 1 (TIM1) to be under positive natural selection in primates.
Urinary L-FABP (show FABP1 Proteins), NGAL (show LCN2 Proteins), Kim-1 and albumin (show ALB Proteins) levels increased during the acute phase of kidney injury and were significantly correlated with the degree of tubulointerstitial fibrosis during the chronic phase. These markers could detect higher risk of progression to CKD.
Blockade of Tim-1 changes Th1 (show HAND1 Proteins)/Th2 balance and reduces circulating regulatory T cells to enhance atherosclerosis in LDL receptor (show LDLR Proteins) knockout mice.
Our results suggest that KIM-1 is an endogenous protective mechanism against renal ischemia-reperfusion injury
data suggest that TIM-1 signaling plays a direct role in Breg maintenance and induction both under physiological conditions (in response to ACs (show Acsl1 Proteins)) and in response to therapy through TIM-1 ligation
Deletion of the mucin (show SLC13A2 Proteins) domain impaired KIM-1-mediated phagocytic function, resulting in increased proinflammatory cytokine production, decreased antiinflammatory growth factor secretion by proximal epithelial cells, and an increase in tissue macrophages.
Tim-1 is critical for maintaining self-tolerance by regulating IL-10 (show IL10 Proteins) production in Bregs
Tim-1 expression was lower in a herpes simplex virus-induced Behcet's disease (BD) mouse model compared to that in asymptomatic BD normal (BDN) mice.
Tim-1-Fc protects cardiac grafts from chronic rejection by suppressing CD4 (show CD4 Proteins) Th17 development and functionality.
KIM-1 shedding is accelerated by worsening renal cellular injury, and excess soluble KIM-1 competitively inhibits efferocytosis.
Endogenous Tim-1 promotes severe systemic autoimmunity and renal disease MRL-Fas(lpr (show FAS Proteins)) mice.
elevated baseline plasma KIM-1 strongly associated with risk of early progressive renal decline in type 1 diabetes
Urinary KIM-1 levels increased significantly in patients with contrast-induced nephropathy.
Data show that kidney injury molecule (KIM)-1 and neutrophil gelatinase-associated lipocalin (NGAL (show LCN2 Proteins)), were significantly elevated in welding workers post-exposure.
High NGAL (show LCN2 Proteins) and KIM-1 levels may indicate early diabetic kidney injury; however, we did not observe any relationship between these markers and diabetic indices
Kidney injury molecule-1 and neutrophil gelatinase-associated lipocalin (show LCN2 Proteins) excretion rates correlated with excretion rates of other tubular damage markers and predicted outcome in patients with idiopathic membranous nephropathy
The aim of this review article is to summarize the literature data concerning KIM-1 as a potential novel marker in the early diagnosis and prediction of clinical outcome of certain cardiovascular diseases.
Activation of TIM1 (show ARHGEF5 Proteins) by exposing the cells to TIM4 (show TIMD4 Proteins) significantly increased the frequency of apoptotic colon cancer cells. The expression of FasL (show FASL Proteins) was increased in the cancer cells after treating by TIM4 (show TIMD4 Proteins).
Urine KIM1 level was higher in kidney stone patients before lithotripsy than in healthy controls.
Urinary levels of NGAL (show LCN2 Proteins) are more sensitive than uKIM-1 and uL-FABP (show FABP2 Proteins) levels in predicting renal scarring in vesicoureteral reflux.
TIM-1 (show ARHGEF5 Proteins) ligands increase the amount of cell surface protein (show CD28 Proteins), preventing its traffic to the immune synapse
The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene.
hepatitis A virus cellular receptor 1
, T-cell immunoglobulin and mucin domain containing 1
, hepatitis A virus cellular receptor 1 homolog
, kidney injury molecule 1
, t cell immunoglobulin and mucin domain-containing protein 1
, t cell membrane protein 1
, T cell immunoglobin domain and mucin domain protein 1
, T-cell membrane protein 1
, rho guanine nucleotide exchange factor 5