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HDGF encodes a member of the hepatoma-derived growth factor family. Additionally we are shipping HDGF Antibodies (82) and HDGF Kits (29) and many more products for this protein.
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HDGF was overexpressed in hepatocellular carcinoma patients and cells.
miRNA497 directly targets hepatomaderived growth factor (HDGF) in prostate cancer cells.
describe two previously unknown HDGF isoforms, HDGF-B and HDGF-C, generated via alternative splicing with structurally unrelated N-terminal regions of their hath region
study uncovers a novel function of HDGF as a messenger of cellular condition (alarmin) which in-turn modulates cellular function-aspects that could be used as a biomarker for ovarian cancer.
HDGF and beta-catenin (show CTNNB1 Proteins) interact as a positive feedback loop, which plays an important role in carcinogenesis and progression of colorectal carcinoma.
HDGF is important in promoting malignant biological behaviors, including proliferation, migration and invasion of hilar cholangiocarcinoma cells.
Hepatoma-derived growth factor overexpression is involved in liver carcinogenesis.
Meta-analysis results provide evidence that HDGF may be a new indicator of poor cancer prognosis.
HDGF contains conserved N-terminal HATH domains with a characteristic structural motif, namely the PWWP motif. This study defines the role of the first residue of the PWWP motif in modulating HATH domain stability and oligomer formation in binding.
HDGF overexpression is common in early-stage cervical adenocarcinoma.
liver cancer cell-derived HDGF can induce Foxp3 (show FOXP3 Proteins)(+) T cells; the latter has immune suppressor functions on CD8 (show CD8A Proteins)(+) T cell activities
Up-regulation of hepatoma-derived growth factor facilities tumor progression in malignant melanoma.
HDGF promotes tumor progression after secondary upregulation and may represent another protein fitting into the concept of non-oncogene (show RAB1A Proteins) addiction of tumor tissue.
HDGF exploits the innate properties of both cell surface heparan sulfates and membrane receptor via the HATH domain to affect related cell signalling processes
HDGF plays a pro-fibrogenic role during liver fibrosis in mice through activation of TGF-beta (show TGFB1 Proteins) pathway.
Hepatoma-derived growth factor stimulates cell growth after translocation to the nucleus
Hepatoma-derived growth factor helps regulate the hepatocyte proliferation in liver development.
Increased HDGF expression is correlated with disease progression of hepatocellular carcinoma and represent a specific prognostic factor in patient with liver cancer.
we investigated the role of HDGF in tumorigenesis and elucidated the mechanism of action.
HDGF is a novel type of neurotrophic factor (show NTF3 Proteins) harbored in the nucleus and it functions in an autocrine manner.
HDGF is synthesized similarly by the endometrium and embryo, and it may exert embryotropic effects by autocrine and/or paracrine mechanisms.
involvement of HDGF during the initiation phase of the apoptotic process downstream from an initiator Caspase (show CASP3 Proteins) and regulation of this protein by phosphorylation in the nucleus
This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. This gene was thought initially to be located on chromosome X, however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described.
hepatoma-derived growth factor (high-mobility group protein 1-like)
, hepatoma-derived growth factor
, high mobility group protein 1-like 2