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Enhances DNA synthesis and may play a role in cell proliferation (By similarity).. Additionally we are shipping Hepatoma-Derived Growth Factor-Related Protein 3 Antibodies (43) and Hepatoma-Derived Growth Factor-Related Protein 3 Kits (3) and many more products for this protein.
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Human HDGFRP3 Protein expressed in Escherichia coli (E. coli) - ABIN667650
Abouzied, Baader, Dietz, Kappler, Gieselmann, Franken et al.: Expression patterns and different subcellular localization of the growth factors HDGF (hepatoma-derived growth factor) and HRP-3 (HDGF-related protein-3) suggest functions in addition to their ... in The Biochemical journal 2004
Show all 2 references for ABIN667650
Glucose deprivation-induced HRP-3 up-regulation potentially plays a major role in protecting hepatocellular carcinoma cells against apoptosis caused by energy pressure.
Depletion of HRP-3 induces apoptosis of radio- and chemoresistant A549 cells. HRP-3 is essential for regulating reactive oxygen species-dependent, p53 (show TP53 Proteins)-induced cell death.
LEDGF/p75 (show PSIP1 Proteins) and HRP2 (show HDGFRP2 Proteins) IBDs avidly bind HIV-1 Integrase, share a similar domain organization and have an evident evolutionary and likely functional relationship
Hepatoma-derived growth factor-related protein-3 interacts with microtubules and promotes neurite outgrowth in mouse cortical neurons
Antibody-mediated neutralization of HRP-3 function results in neuronal degeneration; this protein also exerts a neurite outgrowth-promoting effect when it is presented as a coated substrate but not as a soluble factor.
Enhances DNA synthesis and may play a role in cell proliferation (By similarity).
hepatoma-derived growth factor 2
, hepatoma-derived growth factor-related protein 3