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Hepcidin Antimicrobial Peptide Proteins (HAMP)

The product encoded by HAMP is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. Additionally we are shipping Hepcidin Antibodies (105) and Hepcidin Kits (71) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HAMP 57817 P81172
HAMP 84506 Q9EQ21
HAMP 84604 Q99MH3
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Top Hepcidin Proteins at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Rat His tag,GST tag 100 μg Log in to see 11 to 13 Days
$721.60
Details
HOST_Escherichia coli (E. coli) Wild boar His tag,GST tag 100 μg Log in to see 11 to 13 Days
$739.20
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$387.20
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Mouse His tag,S tag   100 μg Log in to see 11 to 13 Days
$704.00
Details
HOST_Synthetic Human Ovalbumin   100 μg Log in to see 11 to 13 Days
$616.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$574.35
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$889.07
Details
HOST_Escherichia coli (E. coli) Rat Un-conjugated   100 μg Log in to see 9 to 19 Days
$904.80
Details
HOST_Escherichia coli (E. coli) Pig Un-conjugated   100 μg Log in to see 9 to 19 Days
$920.54
Details

HAMP Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,
,
Rat (Rattus) ,
,

More Proteins for Hepcidin Antimicrobial Peptide (HAMP) Interaction Partners

Zebrafish Hepcidin Antimicrobial Peptide (HAMP) interaction partners

  1. The data also show that the antibacterial activity of hepcidin-2 depends upon the disulfide bridges.

  2. data support an alternative mechanism for hepcidin regulation during zebrafish embryonic development, which is independent of hemojuvelin (show HFE2 Proteins).

  3. Hepcidin expression is regulated by a transferrin-a (show Tf Proteins)-dependent pathway in the zebrafish embryo.

Human Hepcidin Antimicrobial Peptide (HAMP) interaction partners

  1. Hepcidin levels are higher in NAFLD with iron overload.

  2. Systemic inflammation and elevated values of IL-6 (show IL6 Proteins) present in exacerbations and stabile chronic obstructive pulmonary disease might be responsible for the observed increased hepcidin level.

  3. The concentration of functional membrane-associated ferroportin (show SLC40A1 Proteins) is controlled by its ligand, the iron-regulatory hormone hepcidin, and fine-tuned by regulatory mechanisms serving iron homeostasis, oxygen utilization, host defense, and erythropoiesis.

  4. The serum hepcidin, ferritin, alanine transaminase, aspartate transaminase, gamma-glutamyltransferase and bilirubin were examined in two independent Chinese cohorts consisted of 3455 individuals.

  5. Hepcidin-25 shows a strong positive correlation with ferritin (show FTL Proteins), and also correlates positively with CRP (show CRP Proteins), in this patient population.

  6. the effect of alpha-1-antitrypsin (A1AT (show SERPINA1 Proteins)) on the expression of the iron hormone hepcidin

  7. Hepcidin levels are decreased independently from hs-CRP (show CRP Proteins) levels as a compensatory mechanism to increase the iron absorption in response to decreased serum iron levels in patients with RVD.

  8. erythropoietic drive, iron status, and inflammation all contribute to variation in hepcidin level.

  9. gonadotropin-stimulated endogenous estrogen markedly decreases circulating hepcidin-25 levels

  10. Identify 3 heterozygous missense mutations in BMP6 (show BMP6 Proteins) in patients with unexplained iron overload. These mutations lead to loss of signaling to SMAD (show SMAD1 Proteins) proteins and reduced hepcidin production.

Mouse (Murine) Hepcidin Antimicrobial Peptide (HAMP) interaction partners

  1. The results suggest that physiologic hepcidin levels are insufficient to alter Fpn levels within the retinal pigment epithelium and Muller cells, but may limit iron transport into the retina from vascular endothelial cells.

  2. In TNF (show TNF Proteins)(DeltaARE/+) and IL-10 (show IL10 Proteins)(-/-)-mice hepatic hepcidin expression and protein content was significantly lower than in corresponding wild-types.

  3. In Angiotensin II treated mice, duodenal divalent metal transporter-1 (show SLC11A2 Proteins) and ferroportin (show SLC40A1 Proteins) expression levels were increased and hepatic hepcidin mRNA expression and serum hepcidin concentration were reduced.

  4. results clarify how commensal bacteria affect hepcidin expression and reveal a novel connection between IL-1beta and activation of BMP signaling.

  5. Activation of TLR4 (show TLR4 Proteins) signaling and NF-small ka, CyrillicB are involved in the suppression of hepcidin gene transcription by alcohol in the presence of inflammation in the liver.

  6. Study describes extensive blood vessel damage in Alzheimer's disease brain and a reduction in hepcidin and ferroportin (show SLC40A1 Proteins) levels

  7. Hepatic hepcidin plays an important role in sepsis through regulation of iron metabolism

  8. Hepc1(-/-) mice had a phenotype of low bone mass and alteration of the bone microarchitecture, most likely caused by a decreased osteoblastic activity

  9. Hepcidin mRNA expression was increased in the D-galactose (D-gal (show GAL Proteins)) group, decreased in the caloric restriction (CR) group, and was basically unchanged in the D-gal (show GAL Proteins)-CR group.

  10. results provide evidence that HFE (show HFE Proteins) induces hepcidin expression via the BMP pathway: HFE (show HFE Proteins) interacts with ALK3 (show BMPR1A Proteins) to stabilize ALK3 (show BMPR1A Proteins) protein and increase ALK3 (show BMPR1A Proteins) expression at the cell surface.

Pig (Porcine) Hepcidin Antimicrobial Peptide (HAMP) interaction partners

  1. this study demonstrates that urine hepcidin-25 concentrations strongly correlate with hepatic hepcidin mRNA abundance, plasma hepcidin-25 levels, iron transferrin (show Tf Proteins) saturation and non-heme liver iron levels.

  2. Data suugest that hepcidin might had antiinflammatory function and is a candidate regulator of the cross-talk between iron regulation and inflammation.

  3. report the full-length cDNA sequences of porcine hepcidin and liver-expressed antimicrobial peptide-2 (LEAP-2 (show LEAP2 Proteins))

Horse (Equine) Hepcidin Antimicrobial Peptide (HAMP) interaction partners

Rainbow Trout (Oncorhynchus mykiss) Hepcidin Antimicrobial Peptide (HAMP) interaction partners

  1. Hepcidin peptide is up-regulated by iron and bacterial components in the trout liver.

Hepcidin (HAMP) Protein Profile

Protein Summary

The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure.

Gene names and symbols associated with HAMP

  • hepcidin antimicrobial peptide (HAMP)
  • hepcidin antimicrobial peptide 1 (hamp1)
  • hepcidin antimicrobial peptide (Hamp)
  • hepcidin antimicrobial peptide (hamp)
  • HAMP protein
  • Hamp1 protein
  • Hepc protein
  • Hepc1 protein
  • Hepcidin protein
  • HFE2B protein
  • LEAP1 protein
  • PLTR protein

Protein level used designations for HAMP

hepcidin antimicrobial peptide , antimicrobial peptide , hepcidin-1 , iron regulatory peptide , preprohepcidin 1 , hepcidin , liver-expressed antimicrobial peptide 1 , putative liver tumor regressor , hepcidin antimicrobial peptide 1 , antimicrobial peptide hepcidin , putative hepcidin antibacterial peptide

GENE ID SPECIES
744861 Pan troglodytes
708397 Macaca mulatta
402837 Danio rerio
57817 Homo sapiens
84506 Mus musculus
84604 Rattus norvegicus
100733490 Cavia porcellus
397207 Sus scrofa
492281 Canis lupus familiaris
512301 Bos taurus
100500730 Ovis aries
100050728 Equus caballus
100174758 Pongo abelii
100135935 Oncorhynchus mykiss
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