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Hermansky-Pudlak Syndrome 6 Proteins (HPS6)

This intronless gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Additionally we are shipping HPS6 Antibodies (35) and HPS6 Kits (23) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HPS6 79803 Q86YV9
HPS6 20170 Q8BLY7
Rat HPS6 HPS6 309446 Q7M733
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Top HPS6 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

HPS6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Hermansky-Pudlak Syndrome 6 (HPS6) Interaction Partners

Human Hermansky-Pudlak Syndrome 6 (HPS6) interaction partners

  1. HPS6 interacts with dynactin p150Glued (show DCTN1 Proteins) to mediate retrograde trafficking and maturation of lysosomes

  2. Mutation of the protein-trafficking gene Hps6 increased sensitivity of melanoma cells to cis (show CISH Proteins)-diaminedichloroplatinum II treatment.

  3. Molecular studies showed a variety of mutations in the single exon HPS6 gene, including frame shift, missense, and nonsense mutations as well as a approximately 20 kb deletion spanning the entire HPS6 genomic region.

  4. Component of BLOC-2. Results suggest a common biological basis underlying the pathogenesis of HPS-3 (show HPS3 Proteins), -5 and -6 disease.

Mouse (Murine) Hermansky-Pudlak Syndrome 6 (HPS6) interaction partners

  1. BLOC-2 functions to direct recycling endosomal tubular transport intermediates to maturing melanosomes and thereby promote cargo delivery and optimal pigmentation.

  2. The product of the Mreg(dsu (show MREG Proteins)) locus, melanoregulin (MREG (show MREG Proteins)), interacts both with members of BLOC-2 complex and with ocular albinism in regulating melanosome size.

  3. Data suggest functional links between OCA2 and the BLOC-1, BLOC-2, and AP-3 protein complexes involved in melanosome biogenesis.

  4. The identification of the feeble mutation led to our subsequent observations that AP-3 (show AP3B1 Proteins), as well as the BLOC-1 (show PLDN Proteins) and BLOC-2 are essential for plasmacytoid dendritic cells signaling through TLR7 (show TLR7 Proteins) and TLR9 (show TLR9 Proteins).

HPS6 Protein Profile

Protein Summary

This intronless gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 5 protein. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 6.

Gene names and symbols associated with HPS6

  • Hermansky-Pudlak syndrome 6 (HPS6)
  • Hermansky-Pudlak syndrome 6 (hps6)
  • Hermansky-Pudlak syndrome 6 (Hps6)
  • 5330434M19Rik protein
  • BLOC2 protein
  • Hsp6 protein
  • RP11-302K17.1 protein
  • ru protein

Protein level used designations for HPS6

Hermansky-Pudlak syndrome 6 , Hermansky-Pudlak syndrome-6 , Hermansky-Pudlak syndrome 6 protein-like , Hermansky-Pudlak syndrome 6 protein , Hermansky-Pudlak syndrome-6 protein (HPS6) , ruby-eye protein homolog , Hermansky-Pudlak syndrome 6 protein homolog , ruby eye , ruby-eye protein , ru , ruby-eye-like protein

GENE ID SPECIES
609471 Canis lupus familiaris
745320 Pan troglodytes
770328 Gallus gallus
100038145 Xenopus (Silurana) tropicalis
100472993 Ailuropoda melanoleuca
79803 Homo sapiens
100049675 Sus scrofa
511792 Bos taurus
20170 Mus musculus
309446 Rattus norvegicus
100720545 Cavia porcellus
101105705 Ovis aries
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