anti-Hermansky-Pudlak Syndrome 1 (HPS1) Antibodies

HPS1 encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Additionally we are shipping HPS1 Kits (12) and HPS1 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HPS1 3257 Q92902
HPS1 192236 O08983
HPS1    
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Top anti-HPS1 Antibodies at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ELISA, WB Figure 1: Western blot analysis using HPS1 mouse mAb against truncated HPS1 recombinant protein (1) and HPS1-hIgGFc transfected CHO-K1 cell lysate (2) . 100 μL Log in to see 2 to 3 Days
$442.20
Details
Human Mouse Un-conjugated ELISA, WB   0.1 mL Log in to see 4 to 6 Days
$495.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: HPS1 Antibody [NBP2-31848] - melanoma Immunohistochemistry: HPS1 Antibody [NBP2-31848] - Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated IF, IHC, WB Immunohistochemistry of paraffin-embedded mouse stomach using HPS1 antibody at dilution of 1:100 (x40 lens). Immunohistochemistry of paraffin-embedded rat kidney using HPS1 antibody at dilution of 1:100 (x40 lens). 100 μL Log in to see 16 Days
$323.13
Details
Human Mouse Un-conjugated WB 100 μL Log in to see 7 to 9 Days
$566.50
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated EIA, WB 0.1 mL Log in to see 6 to 8 Days
$434.50
Details
Human Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 13 to 16 Days
$313.50
Details
Human Rabbit Un-conjugated IF, IHC, WB   50 μL Log in to see 7 to 9 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB   150 μL Log in to see 13 to 16 Days
$753.50
Details

HPS1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human ,
,
,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-HPS1 Antibodies

  1. Human Monoclonal HPS1 Primary Antibody for ELISA, WB - ABIN969198 : Kobashi, Yoshida, Miyashita, Niki, Matsushima: Hermansky-Pudlak syndrome with interstitial pneumonia without mutation of HSP1 gene. in Internal medicine (Tokyo, Japan) 2005 (PubMed)
    Show all 5 Pubmed References

  2. Human Monoclonal HPS1 Primary Antibody for ELISA, WB - ABIN966298 : Nazarian, Falcón-Pérez, DellAngelica: Biogenesis of lysosome-related organelles complex 3 (BLOC-3): a complex containing the Hermansky-Pudlak syndrome (HPS) proteins HPS1 and HPS4. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
    Show all 3 Pubmed References

More Antibodies against HPS1 Interaction Partners

Human Hermansky-Pudlak Syndrome 1 (HPS1) interaction partners

  1. BLOC-3 is a Rab32 (show RAB32 Antibodies) and Rab38 (show RAB38 Antibodies) guanine nucleotide exchange factor (show RASGRF1 Antibodies), with a specific function in the biogenesis of lysosome-related organelles. Silencing of the BLOC-3 subunits Hps1 and Hps4 (show HPS4 Antibodies) results in the mislocalization of Rab32 (show RAB32 Antibodies) and Rab38 (show RAB38 Antibodies).

  2. Seven mutations (six previously unreported) were described in the HPS1, HPS4 (show HPS4 Antibodies), and HPS5 (show HPS5 Antibodies) genes among Hermansky-Pudlak Syndrome patients of Mexican, Uruguayan, Honduran, Cuban, Venezuelan, and Salvadoran ancestries.

  3. a previously unreported missense mutation (G313S) at the 3' splice junction of exon 10 of Hermansky-Pudlak syndrome 1 protein resulted in activation of a cryptic intronic splice site causing an aberrantly spliced HPS1 mRNA

  4. Three different mutations in the HPS1 gene were found in the two families.

  5. Data show that recombinant HPS1-HPS4 (show HPS4 Antibodies) produced in insect cells can be efficiently isolated as a 1:1 heterodimer, and might function as a Rab9 (show RAB9A Antibodies) effector in the biogenesis of lysosome-related organelles.

  6. Description of mutations in HPS genes that cause Hermansky-Pudlak syndrome (review)

  7. Four novel mutations were discovered and the diagnosis of HPS-1, available only on molecular grounds, has important prognostic and treatment implications.

  8. identification as a component of two complexes, BLOC-3 and BLOC-4, involved in the biogenesis of lysosome-related organelles

  9. observations demonstrate that the Hermansky-Pudlak syndrome 1(HPS1) and HPS4 (show HPS4 Antibodies) proteins are components of a cytosolic complex that is involved in the biogenesis of lysosomal-related organelles

  10. Biogenesis of lysosome-related organelles complex 3 (BLOC-3): a complex containing the Hermansky-Pudlak syndrome (HPS) prot (show PLDN Antibodies)eins HPS1 and HPS4.

Mouse (Murine) Hermansky-Pudlak Syndrome 1 (HPS1) interaction partners

  1. This may account for the tight correlation between Hps1 with Ptbp1 (show PTBP1 Antibodies) expression levels observed across mammalian tissues.

  2. Our study indicates that Ap3b1 (show AP3B1 Antibodies) gene play distinct roles in melanin production and tyrosinase (show TYR Antibodies) distribution compared with Hps1 gene.

  3. The mouse genes for HPS, pale ear and pearl (show AP3B1 Antibodies), orthologous to the human HPS1 and HPS2 (ADTB3A (show AP3B1 Antibodies)) genes, copperate in production of platelet dense granules, melanosomes, and lysosomes.

  4. The coat-color phenotype of young homozygous double-mutant mice deficient in subunits of BLOC-3 (HPS1) and BLOC-1 (pallidin (show PLDN Antibodies)) was indistinguishable from that of BLOC-1 (show PLDN Antibodies) single mutants.

HPS1 Antigen Profile

Protein Summary

This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is a component of three different protein complexes termed biogenesis of lysosome-related organelles complex (BLOC)-3, BLOC4, and BLOC5. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 1. Multiple transcript variants encoding distinct isoforms have been identified for this gene\; the full-length sequences of some of these have not been determined yet.

Gene names and symbols associated with HPS1

  • HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 (HPS1) antibody
  • Hermansky-Pudlak syndrome 1 (HPS1) antibody
  • Hermansky-Pudlak syndrome 1 (hps1) antibody
  • HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 (Hps1) antibody
  • 6030422N11Rik antibody
  • BB405864 antibody
  • ep antibody
  • Hps antibody
  • HPS1 antibody
  • im:7143944 antibody
  • MGC123240 antibody
  • zgc:123240 antibody

Protein level used designations for HPS1

Hermansky-Pudlak syndrome 1 protein , Hermansky-Pudlak syndrome 1 , DKEYP-34H12.4 , Hermansky-Pudlak syndrome 1 protein homolog , Hermansky-Pudlak syndrome protein homolog , pale ear

GENE ID SPECIES
3257 Homo sapiens
280819 Bos taurus
429879 Gallus gallus
563067 Danio rerio
100021072 Monodelphis domestica
100070620 Equus caballus
192236 Mus musculus
100723233 Cavia porcellus
101110375 Ovis aries
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