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HNRNPA2B1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). Additionally we are shipping HNRNPA2B1 Kits (27) and HNRNPA2B1 Proteins (10) and many more products for this protein.
Showing 10 out of 112 products:
Chicken Monoclonal HNRNPA2B1 Primary Antibody for ICC, IHC (fro) - ABIN108622
Kamma, Horiguchi, Wan, Matsui, Fujiwara, Fujimoto, Yazawa, Dreyfuss: Molecular characterization of the hnRNP A2/B1 proteins: tissue-specific expression and novel isoforms. in Experimental cell research 1999
Show all 11 references for ABIN108622
Chicken Monoclonal HNRNPA2B1 Primary Antibody for ICC, IF - ABIN267486
Hou, Lersch, Gee, Ponthier, Lo, Wu, Turck, Koury, Krainer, Mayeda, Conboy: Decrease in hnRNP A/B expression during erythropoiesis mediates a pre-mRNA splicing switch. in The EMBO journal 2002
Show all 2 references for ABIN267486
Human Monoclonal HNRNPA2B1 Primary Antibody for IF, WB - ABIN1449240
Schrödel, Volz, de Marco: Fusion tags and chaperone co-expression modulate both the solubility and the inclusion body features of the recombinant CLIPB14 serine protease. in Journal of biotechnology 2005
Dog (Canine) Polyclonal HNRNPA2B1 Primary Antibody for WB - ABIN2776584
Goina, Skoko, Pagani: Binding of DAZAP1 and hnRNPA1/A2 to an exonic splicing silencer in a natural BRCA1 exon 18 mutant. in Molecular and cellular biology 2008
Human Monoclonal HNRNPA2B1 Primary Antibody for IF, ELISA - ABIN561313
McDonald, Aulas, Destroismaisons, Pickles, Beleac, Camu, Rouleau, Vande Velde: TAR DNA-binding protein 43 (TDP-43) regulates stress granule dynamics via differential regulation of G3BP and TIA-1. in Human molecular genetics 2011
Human Polyclonal HNRNPA2B1 Primary Antibody for IF, ELISA - ABIN1533660
Kozu, Henrich, Schäfer: Structure and expression of the gene (HNRPA2B1) encoding the human hnRNP protein A2/B1. in Genomics 1995
results demonstrate that hnRNPA2/B1 promotes tumor cell growth by activating COX-2 (show COX2 Antibodies) signaling in NSCLC cells and imply that the hnRNPA2/B1/COX-2 (show COX2 Antibodies) pathway may be a potential therapeutic target for human lung cancers.
Detection of hnRNP A2/B1 expression may be useful as a biomarker for prediction of glioma progression.
The results indicate both genetic and physical interactions between disease-linked RNA-binding proteinss and DNAJB6/mrj (show DNAJB6 Antibodies), suggesting etiologic overlap between the pathogenesis of adult-onset inherited myopathies initiated by mutations in hnRNPA2B1 and DNAJB6 (show DNAJB6 Antibodies).
hnRNPA2B1, hnRNPD (show HNRNPD Antibodies), hnRNPL (show HNRNPL Antibodies) , and YBX1 (show YBX1 Antibodies) might play important roles in gastric cancer tumorigenesis.
A unique role of the embryonic miR (show MLXIP Antibodies)-369-HNRNPA2B1 axis in controlling metabolic enzyme function.
lowering the levels of hnRNP A1 (show HNRNPA1 Antibodies)/A2 elicits defective transcription elongation on a fraction of P-TEFb (show CCNT1 Antibodies)-dependent genes, hence favoring the transcription of P-TEFb (show CCNT1 Antibodies)-independent genes
Study finds that the RNA-binding protein (show PTBP1 Antibodies) HNRNPA2B1 binds m(6)A-bearing RNAs in vivo and in vitro and its biochemical footprint matches the m(6)A consensus motif. HNRNPA2B1 directly binds a set of nuclear transcripts and elicits similar alternative splicing effects as the m(6)A writer METTL3 (show METTL3 Antibodies).
Nuclear TDP-43 (show TARDBP Antibodies) becomes neurotoxic by escaping from the inhibitory regulation by hnRNP-U (show HNRNPU Antibodies) or hnRNP (show HNRNPC Antibodies)-A2.
Tissue analysis and knockdown of hnRNPA2B1 using siRNA subsequently demonstrated both the overexpression and potential role for this molecule in lung tumorigenesis.
Cytoplasmic hnRNPA2 may affect the cancer cell phenotype through 3'-UTR (show UTS2R Antibodies) mRNA-mediated regulation of beta-catenin (show CTNNB1 Antibodies) expression and other cancer-relevant genes.
Findings suggest that hnRNP A2/B1 has an important role in regulation of the innate immune system, especially at the level of monocyte/macrophage activation.
hnRNPA2/B1 plays a functional role in SMC differentiation from stem cells in vitro and embryonic branchial arch artery development.
splicing repressors hnRNP A1 and A2, as well as the polypyrimidine-tract-binding protein PTB, contribute to control of pyruvate kinase isoform M1 and M2 expression
overproduction of TNF-alpha (show TNF Antibodies) leads to aberrant expression of hnRNP (show HNRNPH2 Antibodies)-A2 in the rheumatoid joint and subsequently to autoimmune reactions, which may enhance the inflammatory and destructive process.
These results are consistent with a model where hnRNP E1 (show PCBP1 Antibodies) recruited to A2RE RNA granules by binding to hnRNP (show HNRNPH2 Antibodies) A2 inhibits translation of A2RE RNA during granule transport.
Active Fyn (show FYN Antibodies) phosphorylates hnRNP (show HNRNPH2 Antibodies) A2 and stimulates translation of an myelin basic protein (MBP (show MBP Antibodies)) A2RE (A2 response element) -containing reporter construct.
A common mechanism of mitochondrial respiratory stress-induced activation of nuclear target genes that involves hnRNP (show HNRNPH2 Antibodies) A2 as a transcription coactivator, is described.
This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms.
heterogeneous nuclear ribonucleoprotein A2/B1
, Heterogeneous nuclear ribonucleoprotein A2 homolog 1
, heterogeneous nuclear ribonucleoproteins A2/B1
, hnRNP A2 / hnRNP B1
, nuclear ribonucleoprotein particle A2 protein
, hnRNP A2/B1
, heterogenous nuclear ribonucleoprotein A2/B1
, heterogeneous nuclear ribonucleoprotein A2
, heterogeneous nuclear ribonucleoprotein B0a
, heterogeneous nuclear ribonucleoprotein B0b
, heterogeneous nuclear ribonucleoprotein B1