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Heterogeneous Nuclear Ribonucleoprotein A2/B1 Proteins (HNRNPA2B1)

HNRNPA2B1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). Additionally we are shipping HNRNPA2B1 Antibodies (91) and HNRNPA2B1 Kits (35) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HNRNPA2B1 100359650  
HNRNPA2B1 3181 P22626
HNRNPA2B1 53379 O88569
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Top HNRNPA2B1 Proteins at antibodies-online.com

Showing 9 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Saguinus oedipus His tag   1 mg Log in to see 56 to 66 Days
$2,924.17
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,924.17
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,960.83
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 11 to 13 Days
$844.80
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$1,014.95
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

HNRNPA2B1 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Human , ,
,
Mouse (Murine)

More Proteins for Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1) Interaction Partners

Human Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1) interaction partners

  1. hnRNPA2B1, hnRNPD (show HNRNPD Proteins), hnRNPL (show HNRNPL Proteins) , and YBX1 (show YBX1 Proteins) might play important roles in gastric cancer tumorigenesis.

  2. A unique role of the embryonic miR (show MLXIP Proteins)-369-HNRNPA2B1 axis in controlling metabolic enzyme function.

  3. lowering the levels of hnRNP A1 (show HNRNPA1 Proteins)/A2 elicits defective transcription elongation on a fraction of P-TEFb (show CCNT1 Proteins)-dependent genes, hence favoring the transcription of P-TEFb (show CCNT1 Proteins)-independent genes

  4. Study finds that the RNA-binding protein (show PTBP1 Proteins) HNRNPA2B1 binds m(6)A-bearing RNAs in vivo and in vitro and its biochemical footprint matches the m(6)A consensus motif. HNRNPA2B1 directly binds a set of nuclear transcripts and elicits similar alternative splicing effects as the m(6)A writer METTL3 (show METTL3 Proteins).

  5. Nuclear TDP-43 (show TARDBP Proteins) becomes neurotoxic by escaping from the inhibitory regulation by hnRNP-U (show HNRNPU Proteins) or hnRNP (show HNRNPC Proteins)-A2.

  6. Tissue analysis and knockdown of hnRNPA2B1 using siRNA subsequently demonstrated both the overexpression and potential role for this molecule in lung tumorigenesis.

  7. Cytoplasmic hnRNPA2 may affect the cancer cell phenotype through 3'-UTR mRNA-mediated regulation of beta-catenin (show CTNNB1 Proteins) expression and other cancer-relevant genes.

  8. TDP-43 (show TARDBP Proteins) suppresses CGG-mediated toxicity through interactions with hnRNP A2/B1 and suggest a convergence of pathogenic cascades between repeat expansion disorders and RNA-binding proteins implicated in neurodegenerative disease.

  9. data suggest that a prominent down-regulation of hnRNP-A2/B1 during hypoxia is associated with the post-transcriptional suppression of hASH1 (show ASCL1 Proteins) synthesis.

  10. In KRAS-dependent pancreatic ductal adenocarcinoma cell lines, HNRNPA2B1 interacts with and regulates the activity of KRAS G12V and G12D.

Mouse (Murine) Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1) interaction partners

  1. Findings suggest that hnRNP A2/B1 has an important role in regulation of the innate immune system, especially at the level of monocyte/macrophage activation.

  2. hnRNPA2/B1 plays a functional role in SMC differentiation from stem cells in vitro and embryonic branchial arch artery development.

  3. splicing repressors hnRNP A1 and A2, as well as the polypyrimidine-tract-binding protein PTB, contribute to control of pyruvate kinase isoform M1 and M2 expression

  4. overproduction of TNF-alpha (show TNF Proteins) leads to aberrant expression of hnRNP (show HNRNPH2 Proteins)-A2 in the rheumatoid joint and subsequently to autoimmune reactions, which may enhance the inflammatory and destructive process.

  5. These results are consistent with a model where hnRNP E1 (show PCBP1 Proteins) recruited to A2RE RNA granules by binding to hnRNP (show HNRNPH2 Proteins) A2 inhibits translation of A2RE RNA during granule transport.

  6. Active Fyn (show FYN Proteins) phosphorylates hnRNP (show HNRNPH2 Proteins) A2 and stimulates translation of an myelin basic protein (MBP (show MBP Proteins)) A2RE (A2 response element) -containing reporter construct.

  7. A common mechanism of mitochondrial respiratory stress-induced activation of nuclear target genes that involves hnRNP (show HNRNPH2 Proteins) A2 as a transcription coactivator, is described.

HNRNPA2B1 Protein Profile

Protein Summary

This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms.

Gene names and symbols associated with HNRNPA2B1

  • heterogeneous nuclear ribonucleoprotein A2/B1 (hnrpa2b1)
  • heterogeneous nuclear ribonucleoprotein A2/B1 (HNRNPA2B1)
  • heterogeneous nuclear ribonucleoprotein A2/B1 (hnrnpa2b1)
  • heterogeneous nuclear ribonucleoprotein A2/B1 (LOC100359650)
  • heterogeneous nuclear ribonucleoprotein A2/B1 (LOC100359712)
  • heterogeneous nuclear ribonucleoprotein A2/B1 (Hnrnpa2b1)
  • heterogeneous nuclear ribonucleoprotein A2/B1-like (LOC100353281)
  • 9130414A06Rik protein
  • hnRNP protein
  • hnrnp-A protein
  • HNRNPA2 protein
  • HNRNPA2B1 protein
  • HNRNPB1 protein
  • Hnrpa2 protein
  • Hnrpa2b1 protein
  • HNRPB1 protein
  • MGC53135 protein
  • RNPA2 protein
  • SNRPB1 protein

Protein level used designations for HNRNPA2B1

heterogeneous nuclear ribonucleoprotein A2/B1 , Heterogeneous nuclear ribonucleoprotein A2 homolog 1 , heterogeneous nuclear ribonucleoproteins A2/B1 , hnRNP A2 / hnRNP B1 , nuclear ribonucleoprotein particle A2 protein , hnRNP A2/B1 , heterogenous nuclear ribonucleoprotein A2/B1 , heterogeneous nuclear ribonucleoprotein A2 , heterogeneous nuclear ribonucleoprotein B0a , heterogeneous nuclear ribonucleoprotein B0b , heterogeneous nuclear ribonucleoprotein B1

GENE ID SPECIES
380082 Xenopus laevis
463299 Pan troglodytes
549680 Xenopus (Silurana) tropicalis
701821 Macaca mulatta
100359650 Rattus norvegicus
100359712 Rattus norvegicus
100561250 Anolis carolinensis
100583405 Nomascus leucogenys
3181 Homo sapiens
507564 Bos taurus
53379 Mus musculus
362361 Rattus norvegicus
475260 Canis lupus familiaris
100521762 Sus scrofa
420627 Gallus gallus
100715127 Cavia porcellus
101107187 Ovis aries
100353281 Oryctolagus cuniculus
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