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HNRNPK belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). Additionally we are shipping Heterogeneous Nuclear Ribonucleoprotein K Antibodies (162) and Heterogeneous Nuclear Ribonucleoprotein K Proteins (16) and many more products for this protein.
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Data show that heterogeneous nuclear ribonucleoprotein K (hnRNPK) stabilized of cellular FLICE-inhibitory protein (c-FLIP) protein through inhibition of glycogen synthase kinase 3 beta (GSK3beta) Ser9 phosphorylation during the TNF-related aoptosis-inducing ligand (TRAIL)-induced apoptosis.
HhnRNP-K-mediated regulation of NMHC IIA mRNA translation contributes to the control of enucleation in erythropoiesis.
hnRNP K binds miR (show MLXIP ELISA Kits)-122, a mature liver-specific microRNA required for Hepatitis C virus replication.
The authors identified two new human proteins that interact with Ehrlichia chaffeensis EtpE-C: CD147 and heterogeneous nuclear ribonucleoprotein K (hnRNP-K).
Data show that proto-oncogene (show RAB1A ELISA Kits) protein c (show PROC ELISA Kits)-myc (show MYC ELISA Kits) is upregulated by sumoylated heterogeneous nuclear ribonucleoprotein K (hnRNP K) at the translational level in Burkitt's lymphoma cells.
hnRNP K may be a key molecule involved in cell motility in RCC (show XRCC1 ELISA Kits) cells
It describes the identification of heterogeneous nuclear ribonucleoprotein K (hnRNPK) as one of the composite element binding factors(CEBF) that acts as transactivator of PXR (show NR1I2 ELISA Kits) promoter.
RTVP-1 (show GLIPR1 ELISA Kits) regulates glioma cell spreading, migration and invasion and that these effects are mediated via interaction with N-WASP (show WASL ELISA Kits) and by interfering with the inhibitory effect of hnRNPK on the function of this protein.
we investigate the role of hnRNP K in the radioresistance of malignant melanoma cells
These results indicate that dengue virus type 2 and Junin virus induce hnRNP K cytoplasmic translocation to favor viral multiplication.
a previously unidentified function of phosphorylation at this phylogenetically conserved site and implicates hnRNPK as an intracellular molecular target of ERK (show MAPK1 ELISA Kits)-mediated signaling in axon outgrowth.
hnRNP K is essential for successful optic axon regeneration via a novel post-transcriptional regulatory pathway.
A crucial role is reported for hnrpk in axon development in Xenoops laevis.
the cytoplasmic hnRNPK interacts with GSK3beta and regulates its function.
Data implicate hnRNPK in the development of hematological disorders and suggest hnRNPK acts as a tumor suppressor.
These findings functionally integrate K17 (show KRT17 ELISA Kits), hnRNP K, and gene expression along with RSK (show RPS6KA1 ELISA Kits) and CXCR3 (show CXCR3 ELISA Kits) signaling in a keratinocyte-autonomous axis and provide a potential basis for their implication in tumorigenesis
Nova haploinsufficient mice had spontaneous epilepsy
HnRNP K-3' UTR (show UTS2R ELISA Kits) complex inhibits TAK1 (show NR2C2 ELISA Kits) mRNA translation.
hnRNP-K regulates extracellular matrix, cell motility, and angiogenesis pathways. Involvement of the selected genes (Cck (show CCK ELISA Kits), Mmp-3 (show MMP3 ELISA Kits), Ptgs2 (show PTGS2 ELISA Kits), and Ctgf (show CTGF ELISA Kits)) and pathways was validated by gene-specific expression analysis
HNRNPK affects production of the essential NEAT1_2 isoform by negatively regulating its 3'-end polyadenylation by arresting CFIm (show CPSF6 ELISA Kits) complex binding near NEAT1_1's alternative polyadenylation site.
Mitochondrial superoxide production stimulated by adiponectin (show ADIPOQ ELISA Kits) serves as a trigger to initiate the translocation of hnRNP K, which in turn promotes UCP2 (show UCP2 ELISA Kits) expressions in liver.
the mutually antagonistic action of two RNA-binding proteins, Hu and hnRNP K, control the timing of the switch from proliferation to neuronal differentiation through the post-transcriptional regulation of p21 mRNA
insulin (show INS ELISA Kits) activates the import of hnRNP K protein into mitochondria; overexpression of hnRNP K protein modulates insulin (show INS ELISA Kits)-activated mitochondrial gene expression; and insulin (show INS ELISA Kits) treatment stimulates binding of hnRNP K protein to mitochondrial DNA
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference\; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized.
heterogeneous nuclear ribonucleoprotein K
, heterogeneous nuclear ribonucleoprotein k
, heterogenous nuclear ribonucleoprotein K
, heterogeneous nuclear ribonucleoprotein K-like
, dC-stretch binding protein
, transformation upregulated nuclear protein
, hnRNP K
, dC stretch-binding protein
, hnRNP-K protein