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Heterogeneous Nuclear Ribonucleoprotein L Proteins (HNRNPL)

Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Additionally we are shipping HNRNPL Antibodies (69) and HNRNPL Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HNRNPL 3191 P14866
HNRNPL 15388 Q8R081
Rat HNRNPL HNRNPL 80846  
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Top HNRNPL Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Yeast Human His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Wheat germ Human GST tag   2 μg Log in to see 9 Days
$333.33
Details

HNRNPL Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL) Interaction Partners

Human Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL) interaction partners

  1. hnRNPA2B1 (show HNRNPA2B1 Proteins), hnRNPD (show HNRNPD Proteins), hnRNPL , and YBX1 (show YBX1 Proteins) might play important roles in gastric cancer tumorigenesis.

  2. hnRNP L controls inclusion of a broad spectrum of alternative cassette exons in T cells.

  3. The study presents the structural characterization of the RNA recognition motif domains of hnRNP-L and demonstrate their function in repressing exon 4 of SLC2A2 (show SLC2A2 Proteins).

  4. HnRNP C (show HNRNPC Proteins), YB-1 (show YBX1 Proteins) and hnRNP L coordinately enhance skipping of human MUSK (show MUSK Proteins) exon 10 to generate a Wnt (show WNT2 Proteins)-insensitive MuSK (show MUSK Proteins) isoform.

  5. Data suggest that incorporation of 3(S)-methyl-beta-alanine into a short alpha-helical region of nucleic acid binding domain of hnRNP (show HNRNPC Proteins) LL significantly stabilizes helix without affecting its DNA binding properties.

  6. Our results reveal that hnRNP L is a new regulator for CD44 (show CD44 Proteins) V10 exon splicing.

  7. hnRNP K (show HNRNPK Proteins) and hnRNP L may serve as A1CF (show A1CF Proteins)-like cofactors in AID-mediated class switch recombination and somatic hypermutation

  8. Results show that HNRNPL represses splicing when bound to intronic regions upstream of alternative exons, and in contrast, activates splicing when bound to the downstream intron.

  9. hnRNP L is a potential biomarker for the diagnosis of HBV-HCC (show FAM126A Proteins) and show that hnRNP L contributes to HCC (show FAM126A Proteins) progression.

  10. HnRNP L and hnRNP (show HNRNPC Proteins) LL antagonistically modulate PTB (show PTBP1 Proteins)-mediated splicing suppression of CHRNA1 (show CHRNA1 Proteins) pre-mRNA.

Mouse (Murine) Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL) interaction partners

  1. Hnrnpl binds to p53 (show TP53 Proteins) and inhibits its activation in mouse embryonic stem cells.

  2. Aire (show AIRE Proteins)-containing complexes include 7SK RNA, the latter interaction disrupted by HNRNPL knockdown, suggesting that HNRNPL may partake in delivering inactive P-TEFb (show CCNT1 Proteins) to Aire (show AIRE Proteins)

  3. Results identify a cancer-specific mechanism of hnRNP L phosphorylation and subsequent lowering of the caspase (show CASP3 Proteins)-9a/9b ratio, which is required for the tumorigenic capacity of non-small cell lung cancer cells.

  4. identified hnRNP L as a novel Sam68 (show KHDRBS1 Proteins)-interacting protein partner.

  5. Inflammation modulates the interaction of hnRNP I (show PTBP1 Proteins) and hnRNP L with the 3'untranslated region of the murine inducible nitric-oxide synthase (show NOS2 Proteins) mRNA

  6. decreased surface alpha2beta1 results from decreased Itga2 (show ITGA2 Proteins) pre-mRNA splicing regulated by hnRNP L and depends on CA repeat length at a specific site in intron 1

  7. iNOS mRNA degradation is promoted upon binding of hnRNPI and hnRNPL to a destabilizing region within its 3'-UTR

HNRNPL Protein Profile

Protein Summary

Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with HNRNPL

  • RNA-binding protein XlhnRNPL (hnrpl)
  • heterogeneous nuclear ribonucleoprotein L2 (hnrnpl2)
  • heterogeneous nuclear ribonucleoprotein L (HNRNPL)
  • Heterogeneous nuclear ribonucleoprotein L (hnrpl)
  • heterogeneous nuclear ribonucleoprotein L (Hnrnpl)
  • heterogeneous nuclear ribonucleoprotein L (hnrpl)
  • heterogeneous nuclear ribonucleoprotein L (hnrnpl)
  • C79783 protein
  • D830027H13Rik protein
  • hnrnp-L protein
  • HNRNPL protein
  • Hnrpl protein
  • wu:fb53f10 protein
  • wu:fp61c04 protein
  • zgc:55429 protein
  • zgc:66175 protein

Protein level used designations for HNRNPL

RNA-binding protein XlhnRNPL , fb53f10 , fp61c04 , heterogeneous nuclear ribonucleoprotein L , Heterogeneous nuclear ribonucleoprotein L , hnRNP L , heterogenous nuclear ribonucleoprotein L

GENE ID SPECIES
399143 Xenopus laevis
573096 Danio rerio
456012 Pan troglodytes
100196019 Salmo salar
3191 Homo sapiens
15388 Mus musculus
394074 Danio rerio
100380947 Xenopus laevis
80846 Rattus norvegicus
476466 Canis lupus familiaris
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