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anti-Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) Antibodies

HNRNPU belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). Additionally we are shipping Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) Kits (32) and Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HNRNPU 51810 Q8VEK3
HNRNPU 117280  
HNRNPU 3192 Q00839
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Top anti-Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) Antibodies at antibodies-online.com

Showing 10 out of 55 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-HNRNPU Antibody Titration: 0.2-1 ug/mlPositive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Mouse Un-conjugated ICC, FACS, IF, IHC (p), IP, ELISA, WB Western blot showing Anti-hnRNP-U on HeLa cell extracts 50 μL Log in to see 5 to 6 Days
$402.29
Details
Chicken Mouse Un-conjugated IF, IP, IHC, WB Western blot analysis of p120 Catenin on a A431 cell lysate (Human epithelial carcinoma, ATCC CRL-1555). Lane 1: 1:1000, lane 2: 1:2000, lane 3: 1:4000 dilution of the mouse anti-p120 Catenin antibody. Immunofluorescence staining of human fibroblasts. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-HNRNPU Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: ACHN cell lysate WB Suggested Anti-HNRNPU  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: ACHN cell lysate  HNRNPU is strongly supported by BioGPS gene expression data to be expressed in Human ACHN cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated WB Western blot detection of HNRNPU in : K562 , Jurkat and Hela cell lysates (1: 1000 diluted) Predicted band size: 110 kDa.  Observed band size: 110 kDa 100 μL Log in to see 8 to 9 Days
$392.86
Details
Mouse Rabbit Un-conjugated IC, IF, IP, WB 100 μL Log in to see 7 to 8 Days
$418.00
Details
Human Mouse Un-conjugated IF, IHC (p), IP, ELISA, WB Anti-HnRNP U / p120 antibody IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1102132 dilution 10 ug/ml. 50 μL Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$527.15
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Rabbit Anti-Goat IgG at 1: 5000;  TMB staining Read the data in Microplate Reader by 450nm. 100 μL Log in to see 3 to 7 Days
$269.50
Details

HNRNPU Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) Antibodies

  1. Mouse (Murine) Monoclonal HNRNPU Primary Antibody for ICC, FACS - ABIN108578 : Dreyfuss, Choi, Adam: Characterization of heterogeneous nuclear RNA-protein complexes in vivo with monoclonal antibodies. in Molecular and cellular biology 1984 (PubMed)
    Show all 8 references for ABIN108578

  2. Chicken Monoclonal HNRNPU Primary Antibody for IF, IP - ABIN967770 : Eger, Stockinger, Schaffhauser, Beug, Foisner: Epithelial mesenchymal transition by c-Fos estrogen receptor activation involves nuclear translocation of beta-catenin and upregulation of beta-catenin/lymphoid enhancer binding factor-1 transcriptional activity. in The Journal of cell biology 2000 (PubMed)
    Show all 5 references for ABIN967770

  3. Mouse (Murine) Polyclonal HNRNPU Primary Antibody for IC, IF - ABIN2452032 : Kiledjian, Dreyfuss: Primary structure and binding activity of the hnRNP U protein: binding RNA through RGG box. in The EMBO journal 1992 (PubMed)
    Show all 2 references for ABIN2452032

  4. Cow (Bovine) Polyclonal HNRNPU Primary Antibody for WB - ABIN2778892 : Tu, Yan, Hood, Lin: Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells. in Molecular & cellular proteomics : MCP 2007 (PubMed)

More Antibodies against Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) Interaction Partners

Mouse (Murine) Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) interaction partners

  1. findings provide conclusive evidence for the essential role of hnRNP U in heart development and function and in the regulation of alternative splicing.

  2. SAF-A interacts with BRG1 and both components are required for RNA Polymerase II Mediated Transcription

  3. Macrophage expression of hnRNP U was induced by TLR stimulation. hnRNP U knockdown attenuated & overexpression increased TLR-induced expression of TNF-alpha (show TNF Antibodies), IL-6 (show IL6 Antibodies) & IL-1beta (show IL1B Antibodies). hnRNP U bound to the mRNA of these cytokines via the RGG motif.

  4. Data report that endogenous SAF-A is involved in regulation of Oct4 (show POU5F1 Antibodies) expression, binds the Oct4 (show POU5F1 Antibodies) proximal promoter in ES cells, and dissociates from the promoter upon early differentiation induced by LIF (show LIF Antibodies) withdrawal.

  5. hnRNP-U engages a highly neddylated active SCF (show KITLG Antibodies)beta-TrCP (show BTRC Antibodies)which dissociates in the presence of a high-affinity substrate, resulting in the ubiquitination of the latter.

  6. hnRNP U participates in nuclear regulatory events that are involved in mammalian central and peripheral circadian clocks.

  7. nuclear matrix protein SAF-A binds to the 3'-flanking region of the Bmal1 (show ARNTL Antibodies) gene with circadian timing

  8. HnRNP U binding to the 5'-UTR (show UTS2R Antibodies) of the Shh (show SHH Antibodies) facilitates gene expression during limb development.

  9. SAF-A was found to be localized in three different domains: outside the chromosomes, on the surface of the chromosome arms, and in the centromere region where it apparently binds specifically to the satellite DNA.

  10. the c-Myc (show MYC Antibodies)-Max complex exerts its transcriptional regulatory role and hnRNP U may be a coactivator of this transcriptional activator complex.

Human Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) interaction partners

  1. mutual regulatory mechanisms exist between PP4 (show ANXA5 Antibodies) and SAF-A. Interactions between PP4 (show ANXA5 Antibodies) and SAF-A played a role in prometaphase/metaphase transition.

  2. CENP-W (show CENPW Antibodies) interacts with hnRNPU and may contribute to kinetochore-microtubule attachment in mitotic cells.

  3. Nuclear TDP-43 (show TARDBP Antibodies) becomes neurotoxic by escaping from the inhibitory regulation by hnRNP-U or hnRNP (show HNRNPC Antibodies)-A2. hnRNP-U inhibits TDP-43 (show TARDBP Antibodies)-mediated alterations in splicing of POLDIP3 (show POLDIP3 Antibodies) mRNA.

  4. These results suggest that HNRNPU, FAM36A, and NCRNA00201 are not major genes for microcephaly and corpus callosum abnormalities but are good candidates for intellectual disability (ID) and seizures.

  5. both phosphorylation and dephosphorylation of SAF-A serine 59 by PLK1 (show PLK1 Antibodies) and PP2A (show PPP2R4 Antibodies), respectively, are required for accurate and timely exit from mitosis.

  6. demonstrate that H19 inhibits RNA Pol II-mediated transcription by disrupting the hnRNP U-actin complex

  7. Induction of caspase (show CASP3 Antibodies)-9b expression is due to activation of hnRNP L (show HNRNPL Antibodies) via phosphorylation to compete/inhibit hnRNP U association with exon 3 of Casp9 (show CASP9 Antibodies) mRNA.

  8. the hnRNP-U protection of cells after oxidative stress is largely due to enhancement of NEIL1 (show NEIL1 Antibodies)-mediated repair.

  9. experimentally verified the targets heterogeneous nuclear ribonucleoprotein U, phosphatidylinositol-3-OH kinase, the WNK (with-no-lysine) kinase family and USP19 (ubiquitin-specific peptidase 19 (show USP19 Antibodies)) as vulnerable nodes in the host cellular defence system against viruses

  10. SAF-A interacts with BRG1 and both components are required for RNA Polymerase II Mediated Transcription

Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) Antigen Profile

Protein Summary

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they form complexes with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene contains a RNA binding domain and scaffold-associated region (SAR)-specific bipartite DNA-binding domain. This protein is also thought to be involved in the packaging of hnRNA into large ribonucleoprotein complexes. During apoptosis, this protein is cleaved in a caspase-dependent way. Cleavage occurs at the SALD site, resulting in a loss of DNA-binding activity and a concomitant detachment of this protein from nuclear structural sites. But this cleavage does not affect the function of the encoded protein in RNA metabolism. At least two alternatively spliced transcript variants have been identified for this gene.

Gene names and symbols associated with HNRNPU

  • heterogeneous nuclear ribonucleoprotein U (Hnrnpu) antibody
  • heterogeneous nuclear ribonucleoprotein U (LOC100348766) antibody
  • heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) (HNRNPU) antibody
  • heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) (hnrnpu) antibody
  • heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) (Hnrnpu) antibody
  • AA408410 antibody
  • AI256620 antibody
  • AL024194 antibody
  • AL024437 antibody
  • AW557595 antibody
  • C86794 antibody
  • hnRNP U antibody
  • HNRPU antibody
  • saf-a antibody
  • SAFA antibody
  • SN1 antibody
  • Sp120 antibody
  • U21.1 antibody

Protein level used designations for HNRNPU

SAF-A , heterogenous nuclear ribonucleoprotein U , nuclear matrix protein sp120 , scaffold attachment factor A , system N1 Na+ and H+-coupled glutamine transporter , transporter protein , transporter protein; system N1 Na+ and H+-coupled glutamine transporter , heterogeneous nuclear ribonucleoprotein U , p120 nuclear protein , pp120

GENE ID SPECIES
51810 Mus musculus
117280 Rattus norvegicus
100348766 Oryctolagus cuniculus
3192 Homo sapiens
399374 Xenopus laevis
539950 Bos taurus
100515571 Sus scrofa
421492 Gallus gallus
100725944 Cavia porcellus
101107118 Ovis aries
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