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anti-Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) Antibodies

Expression of HEXIM1 is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells. Additionally we are shipping HEXIM1 Proteins (14) and HEXIM1 Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HEXIM1 10614 O94992
HEXIM1 192231 Q8R409
HEXIM1 498008 Q5M9G1
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Top anti-HEXIM1 Antibodies at antibodies-online.com

Showing 10 out of 125 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB HEXIM1 Antibody (N-term)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the HEXIM1 antibody detected the HEXIM1 protein (arrow). HEXIM1 Antibody (N-term)  western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the HEXIM1 antibody detected the HEXIM1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Rabbit Un-conjugated IHC (p), WB HEXIM1 antibody (Center) (ABIN655589) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-HEXIM1 Antibody Titration: 0.6ug/mlELISA Titer: 1:12500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue reacted with AP52035PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of HEXIM1 antibody (Center) in mouse liver tissue lysates (35ug/lane). This demonstrates the HEXIM1 antibody detected the HEXIM1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated ELISA, WB ABIN334418 (0.3µg/ml) staining of 1) HeLa cell lysate and 2) recombinant HEXIM1 (3ng). Detected by chemiluminescence. Data kindly provided by David Price and Jeff Coopper, University of Iowa, USA. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, using HEXIM1 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HeLa cells, using HEXIM1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA, WB Human, Small intestine: Formalin-Fixed Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details

HEXIM1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-HEXIM1 Antibodies

  1. Human Polyclonal HEXIM1 Primary Antibody for EIA, IHC (p) - ABIN952725 : Dow, Liu, Rice: T-loop phosphorylated Cdk9 localizes to nuclear speckle domains which may serve as sites of active P-TEFb function and exchange between the Brd4 and 7SK/HEXIM1 regulatory complexes. in Journal of cellular physiology 2010 (PubMed)
    Show all 4 references for ABIN952725

  2. Human Polyclonal HEXIM1 Primary Antibody for WB - ABIN2801953 : Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003 (PubMed)
    Show all 4 references for ABIN2801953

  3. Mouse (Murine) Polyclonal HEXIM1 Primary Antibody for IHC (p), WB - ABIN655589 : Ogba, Doughman, Chaplin, Hu, Gargesha, Watanabe, Montano: HEXIM1 modulates vascular endothelial growth factor expression and function in breast epithelial cells and mammary gland. in Oncogene 2010 (PubMed)
    Show all 3 references for ABIN655589

  4. Human Polyclonal HEXIM1 Primary Antibody for IHC (p), WB - ABIN657913 : Schönichen, Bigalke, Urbanke, Grzesiek, Dames, Geyer: A flexible bipartite coiled coil structure is required for the interaction of Hexim1 with the P-TEFB subunit cyclin T1. in Biochemistry 2010 (PubMed)
    Show all 3 references for ABIN657913

  5. Human Polyclonal HEXIM1 Primary Antibody for EIA, WB - ABIN375207 : Schulte, Czudnochowski, Barboric, Schönichen, Blazek, Peterlin, Geyer: Identification of a cyclin T-binding domain in Hexim1 and biochemical analysis of its binding competition with HIV-1 Tat. in The Journal of biological chemistry 2005 (PubMed)

  6. Cow (Bovine) Polyclonal HEXIM1 Primary Antibody for WB - ABIN2775783 : Yik, Chen, Nishimura, Jennings, Link, Zhou: Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA. in Molecular cell 2003 (PubMed)

More Antibodies against HEXIM1 Interaction Partners

Human Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) interaction partners

  1. Results show that HEXIM1 is a tumor suppressor in melanoma that responds to nucleotide stress by inhibiting transcription elongation of tumorigenic genes and stabilizing mRNA transcripts of other tumor suppressor genes.

  2. Data indicate the binding of RNA-binding protein (show PTBP1 Antibodies) HEXIM with 7SKsnRNP complex comprising the non-coding RNA 7SK and proteins MePCE (show MEPCE Antibodies) and LARP7 (show LARP7 Antibodies).

  3. PPM1G (show PPM1G Antibodies) phosphatase directly binds 7SK RNA and the kinase inhibitor Hexim1 once P-TEFb (show CCNT1 Antibodies) has been released from the 7SK snRNP (show LSM2 Antibodies).

  4. This study demonstrates a novel role of HEXIM1 in regulating human pluripotent stem cells fate through a P-TEFb (show CCNT1 Antibodies)-independent pathway.

  5. HEXIM1 functions as an AR (androgen receptor (show AR Antibodies)) co-repressor as it physically interacts with the AR and is required for the ability of anti-androgens to inhibit androgen-induced target gene expression and cell proliferation.

  6. the release of P-TEFb (show CCNT1 Antibodies) from the 7SK snRNP (show LSM2 Antibodies) led to increased synthesis of HEXIM1 but not HEXIM2 (show HEXIM2 Antibodies)

  7. There is evidence for a direct interaction between HIF-1alpha (show HIF1A Antibodies) and HEXIM1, and HEXIM1 up-regulated hydroxylation of HIF-1alpha (show HIF1A Antibodies).

  8. P-TEFb/HEXIM1-dependent transcriptional regulation may play a pathophysiological role in RVH and be a novel therapeutic target for mitigating RVH in PAH

  9. results not only identify HEXIM1 as a positive regulator of p53 (show TP53 Antibodies), but also propose a novel molecular mechanism of p53 (show TP53 Antibodies) activation caused by the anti-cancer drugs and compounds.

  10. Changes in Hexim-1 protein expression and cellular distribution significantly influence androgen receptor (show AR Antibodies) activation and transforming growth factor (TGF)-beta (show TGFB1 Antibodies) signaling in prostate cancer progression.

Cow (Bovine) Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) interaction partners

  1. The authors demonstrate that bovine hexamethylene bisacetamide-induced protein 1 (BHEXIM1) inhibits the bovine immunodeficiency virus-mediated BIV LTR transcription. In vivo and in vitro assays show direct binding of BHEXIM1 to the bovine cyclin T1 (show CCNT1 Antibodies).

Mouse (Murine) Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) interaction partners

  1. conclude that HEXIM1 could prevent RV hypertrophy, at least in part, via suppression of myocardial angiogenesis through down-regulation of HIF-1alpha and VEGF in the myocardium under hypoxic condition

  2. HEXIM1 re-expression results in the induction of angiogenesis that allows for the co-ordination of tissue growth and angiogenesis during physiological hypertrophy

  3. re-expression of HEXIM1 in mammary epithelial cells resulted in inhibition of metastasis to the lung

  4. a crucial role for the HEXIM1/P-TEFb (show CCNT1 Antibodies) pathway in the regulation of satellite cell-mediated muscle regeneration and identify HEXIM1 as a potential therapeutic target for degenerative muscular diseases.

  5. Our findings underscore the critical role of CLP-1 in remodeling of the genetic response during hypertrophy and fibrosis.

  6. these results show that the improvement in cardiac function in CLP-1(+/-) mice after ischemia-reperfusion injury is achieved through the potentiation of redox signaling.

  7. CLP-1 and the HAND transcription factors may be part of a genetic program critical to proper heart development, and their perturbation can lead to cardiomyopathy

  8. HEXIM1 plays critical roles in coronary vessel development and myocardial growth

  9. the reduced level of CLP-1 introduced in the background of elevated levels of cyclin T1 (show CCNT1 Antibodies) elevates derepression of P-TEFb (show CCNT1 Antibodies) activity and emphasizes the importance of the role of CLP-1 in the mechanism governing compensatory hypertrophy in cardiomyocytes.

HEXIM1 Antigen Profile

Protein Summary

Expression of this gene is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells. This gene has no introns.

Gene names and symbols associated with HEXIM1

  • hexamethylene bis-acetamide inducible 1 (HEXIM1) antibody
  • hexamethylene bis-acetamide inducible 1 (LOC100339675) antibody
  • hexamethylene bis-acetamide inducible 1 (hexim1) antibody
  • hexamethylene bis-acetamide inducible 1 (Hexim1) antibody
  • 7330426E13Rik antibody
  • Clp-1 antibody
  • Clp1 antibody
  • EDG1 antibody
  • fd44h02 antibody
  • hexim antibody
  • HEXIM1 antibody
  • HIS1 antibody
  • MAQ1 antibody
  • wu:fd44h02 antibody
  • zgc:162976 antibody

Protein level used designations for HEXIM1

hexamethylene bis-acetamide inducible 1 , HMBA-inducible , protein HEXIM1 , protein HEXIM1-like , protein HEXIM , cardiac lineage protein 1 , estrogen down-regulated gene 1 protein , hexamethylene bis-acetamide-inducible protein 1 , hexamethylene bisacetamide-inducible protein , hexamethylene-bis-acetamide-inducible transcript 1 , hexamthylene bis-acetamide inducible 1 , menage a quatre 1 , menage a quatre protein 1 , HMBA-inducible 1

GENE ID SPECIES
454746 Pan troglodytes
716006 Macaca mulatta
100339675 Oryctolagus cuniculus
100601526 Nomascus leucogenys
562319 Danio rerio
10614 Homo sapiens
606811 Canis lupus familiaris
539696 Bos taurus
192231 Mus musculus
498008 Rattus norvegicus
735111 Xenopus laevis
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