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Hexamethylene Bis-Acetamide Inducible 1 Proteins (HEXIM1)

Expression of HEXIM1 is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells. Additionally we are shipping HEXIM1 Antibodies (121) and HEXIM1 Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HEXIM1 10614 O94992
HEXIM1 192231 Q8R409
HEXIM1 498008 Q5M9G1
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Top HEXIM1 Proteins at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$583.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,750.00
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,856.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,858.17
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,970.00
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Log in to see 3 to 4 Days
$5,769.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$777.50
Details

HEXIM1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

Top referenced HEXIM1 Proteins

  1. Human HEXIM1 Protein expressed in Escherichia coli (E. coli) - ABIN668055 : Li, Cooper, Altwerger, Feldkamp, Shea, Price: HEXIM1 is a promiscuous double-stranded RNA-binding protein and interacts with RNAs in addition to 7SK in cultured cells. in Nucleic acids research 2007 (PubMed)
    Show all 2 references for ABIN668055

More Proteins for Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) Interaction Partners

Human Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) interaction partners

  1. Results show that HEXIM1 is a tumor suppressor in melanoma that responds to nucleotide stress by inhibiting transcription elongation of tumorigenic genes and stabilizing mRNA transcripts of other tumor suppressor genes.

  2. Data indicate the binding of RNA-binding protein (show PTBP1 Proteins) HEXIM with 7SKsnRNP complex comprising the non-coding RNA 7SK and proteins MePCE (show MEPCE Proteins) and LARP7 (show LARP7 Proteins).

  3. PPM1G (show PPM1G Proteins) phosphatase directly binds 7SK RNA and the kinase inhibitor Hexim1 once P-TEFb (show CCNT1 Proteins) has been released from the 7SK snRNP (show LSM2 Proteins).

  4. This study demonstrates a novel role of HEXIM1 in regulating human pluripotent stem cells fate through a P-TEFb (show CCNT1 Proteins)-independent pathway.

  5. HEXIM1 functions as an AR (androgen receptor (show AR Proteins)) co-repressor as it physically interacts with the AR and is required for the ability of anti-androgens to inhibit androgen-induced target gene expression and cell proliferation.

  6. the release of P-TEFb (show CCNT1 Proteins) from the 7SK snRNP (show LSM2 Proteins) led to increased synthesis of HEXIM1 but not HEXIM2 (show HEXIM2 Proteins)

  7. There is evidence for a direct interaction between HIF-1alpha (show HIF1A Proteins) and HEXIM1, and HEXIM1 up-regulated hydroxylation of HIF-1alpha (show HIF1A Proteins).

  8. P-TEFb/HEXIM1-dependent transcriptional regulation may play a pathophysiological role in RVH and be a novel therapeutic target for mitigating RVH in PAH

  9. results not only identify HEXIM1 as a positive regulator of p53 (show TP53 Proteins), but also propose a novel molecular mechanism of p53 (show TP53 Proteins) activation caused by the anti-cancer drugs and compounds.

  10. Changes in Hexim-1 protein expression and cellular distribution significantly influence androgen receptor (show AR Proteins) activation and transforming growth factor (TGF)-beta (show TGFB1 Proteins) signaling in prostate cancer progression.

Cow (Bovine) Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) interaction partners

  1. The authors demonstrate that bovine hexamethylene bisacetamide-induced protein 1 (BHEXIM1) inhibits the bovine immunodeficiency virus-mediated BIV LTR transcription. In vivo and in vitro assays show direct binding of BHEXIM1 to the bovine cyclin T1 (show CCNT1 Proteins).

Mouse (Murine) Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) interaction partners

  1. conclude that HEXIM1 could prevent RV hypertrophy, at least in part, via suppression of myocardial angiogenesis through down-regulation of HIF-1alpha and VEGF in the myocardium under hypoxic condition

  2. HEXIM1 re-expression results in the induction of angiogenesis that allows for the co-ordination of tissue growth and angiogenesis during physiological hypertrophy

  3. re-expression of HEXIM1 in mammary epithelial cells resulted in inhibition of metastasis to the lung

  4. a crucial role for the HEXIM1/P-TEFb (show CCNT1 Proteins) pathway in the regulation of satellite cell-mediated muscle regeneration and identify HEXIM1 as a potential therapeutic target for degenerative muscular diseases.

  5. Our findings underscore the critical role of CLP-1 (show CNNM1 Proteins) in remodeling of the genetic response during hypertrophy and fibrosis.

  6. these results show that the improvement in cardiac function in CLP-1 (show CNNM1 Proteins)(+/-) mice after ischemia-reperfusion injury is achieved through the potentiation of redox signaling.

  7. CLP-1 (show CNNM1 Proteins) and the HAND transcription factors may be part of a genetic program critical to proper heart development, and their perturbation can lead to cardiomyopathy

  8. HEXIM1 plays critical roles in coronary vessel development and myocardial growth

  9. the reduced level of CLP-1 (show CNNM1 Proteins) introduced in the background of elevated levels of cyclin T1 (show CCNT1 Proteins) elevates derepression of P-TEFb (show CCNT1 Proteins) activity and emphasizes the importance of the role of CLP-1 (show CNNM1 Proteins) in the mechanism governing compensatory hypertrophy in cardiomyocytes.

HEXIM1 Protein Profile

Protein Summary

Expression of this gene is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells. This gene has no introns.

Gene names and symbols associated with HEXIM1

  • hexamethylene bis-acetamide inducible 1 (HEXIM1)
  • hexamethylene bis-acetamide inducible 1 (LOC100339675)
  • hexamethylene bis-acetamide inducible 1 (hexim1)
  • hexamethylene bis-acetamide inducible 1 (Hexim1)
  • 7330426E13Rik protein
  • Clp-1 protein
  • Clp1 protein
  • EDG1 protein
  • fd44h02 protein
  • hexim protein
  • HEXIM1 protein
  • HIS1 protein
  • MAQ1 protein
  • wu:fd44h02 protein
  • zgc:162976 protein

Protein level used designations for HEXIM1

hexamethylene bis-acetamide inducible 1 , HMBA-inducible , protein HEXIM1 , protein HEXIM1-like , protein HEXIM , cardiac lineage protein 1 , estrogen down-regulated gene 1 protein , hexamethylene bis-acetamide-inducible protein 1 , hexamethylene bisacetamide-inducible protein , hexamethylene-bis-acetamide-inducible transcript 1 , hexamthylene bis-acetamide inducible 1 , menage a quatre 1 , menage a quatre protein 1 , HMBA-inducible 1

GENE ID SPECIES
454746 Pan troglodytes
716006 Macaca mulatta
100339675 Oryctolagus cuniculus
100601526 Nomascus leucogenys
562319 Danio rerio
10614 Homo sapiens
606811 Canis lupus familiaris
539696 Bos taurus
192231 Mus musculus
498008 Rattus norvegicus
735111 Xenopus laevis
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