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High Mobility Group Nucleosome Binding Domain 1 Proteins (HMGN1)

The protein encoded by HMGN1 binds nucleosomal DNA and is associated with transcriptionally active chromatin. Additionally we are shipping HMGN1 Antibodies (95) and HMGN1 Kits (26) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HMGN1 15312 P18608
HMGN1 3150 P05114
Rat HMGN1 HMGN1 360704  
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Top HMGN1 Proteins at antibodies-online.com

Showing 10 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$756.80
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$806.30
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,174.33
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Log in to see 3 to 4 Days
$5,769.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$467.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

HMGN1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
,
Human , , ,
, ,

Top referenced HMGN1 Proteins

  1. Human HMGN1 Protein expressed in Escherichia coli (E. coli) - ABIN667774 : Landsman, McBride, Soares, Crippa, Srikantha, Bustin: Chromosomal protein HMG-14. Identification, characterization, and chromosome localization of a functional gene from the large human multigene family. in The Journal of biological chemistry 1989 (PubMed)

  2. Human HMGN1 Protein expressed in Wheat germ - ABIN1306822 : Mangé, Lacombe, Bascoul-Mollevi, Jarlier, Lamy, Rouanet, Maudelonde, Solassol: Serum autoantibody signature of ductal carcinoma in situ progression to invasive breast cancer. in Clinical cancer research : an official journal of the American Association for Cancer Research 2012 (PubMed)

More Proteins for High Mobility Group Nucleosome Binding Domain 1 (HMGN1) Interaction Partners

Mouse (Murine) High Mobility Group Nucleosome Binding Domain 1 (HMGN1) interaction partners

  1. Suggest Hmgn1/Cebpb (show CEBPB Proteins) signaling may play an important role during mouse decidualization.

  2. our findings show that HMGN1 contributes to antitumor immunity and it may offer an effective adjuvant to heighten responses to cancer vaccines.

  3. in mice, loss of HMGN1 leads to transcription changes that accelerate the progression of DEN-induced hepatocarcinogenesis, without affecting the type of tumors or the final total tumor burden of these mice.

  4. HMGN1 is a nucleosome remodeling protein encoded on chromosome 21q22 that suppresses H3K27me3 and promotes both B cell proliferation in vitro and B-ALL in vivo

  5. HMGN1 binds to CpG island-containing promoters and affects the organization of nucleosomes, DNase I (show DNASE1 Proteins) hypersensitivity, and the transcriptional profile of mouse embryonic stem cells and neural progenitors.

  6. Phenotypic analysis of Hmgn1(tm1/tm1 (show TPM2 Proteins)), Hmgn3 (show HMGN3 Proteins)(tm1/tm1 (show TPM2 Proteins)), and Hmgn5 (show HMGN5 Proteins)(tm1/tm1 (show TPM2 Proteins)) mice and their wild type littermates with a battery of standardized tests uncovered variant-specific abnormalities.

  7. a regulatory role for HMGN1 in PARP-1 (show PARP1 Proteins) activation.

  8. extracellular HMGN1 acts as a novel alarmin critical for LPS (show TLR4 Proteins)-induced development of innate and adaptive immune responses.

  9. HMGN1 regulates the expression of methyl CpG-binding protein 2 (MECP2 (show MECP2 Proteins)) in mouse and human, and affects the behavior of mice

  10. Regulation of Hmgn1 and Fgf18 (show FGF18 Proteins) at the digit-interdigit junction suggests retinoic acid controls tissue remodeling as well as apoptosis.

Human High Mobility Group Nucleosome Binding Domain 1 (HMGN1) interaction partners

  1. RNA-seq evidence of biallelic expression of HMGN1 and 10 neighboring genes in at least one primary human tissue tested indicates that the expression of HMGN1 is uncoupled from the control of the maternally inherited 5mCpG imprints at the WRB (show WRB Proteins) differentially methylated region (DMR (show WDR20 Proteins)) in disomic controls or trisomy (Down syndrome) individuals.

  2. HMGN1 can serve as a useful clinical parameter for evaluating disease progression and predicting the outcomes for early-stage patients with non-small cell lung cancer .

  3. nucleosome binding protein HMGN1 as a new PCNA (show PCNA Proteins)-interacting protein that enhances the binding of PCNA (show PCNA Proteins) to chromatin

  4. extracellular HMGN1 acts as a novel alarmin critical for LPS (show IRF6 Proteins)-induced development of innate and adaptive immune responses.

  5. HMGN1 regulates the expression of methyl CpG-binding protein 2 (MECP2 (show MECP2 Proteins)) in mouse and human, and affects the behavior of mice

  6. HMGN1 is not randomly distributed throughout the genome. Instead, the protein preferentially localizes to DNase I (show DNASE1 Proteins) hypersensitive (HS) sites, promoters, functional enhancers, and transcription factor binding sites.

  7. Results show that four serine residues, i.e., Ser6, Ser85, Ser88, and Ser98, can be phosphorylated in high mobility group (show SSRP1 Proteins) N1 (HMGN1).

  8. HMGN1 optimizes the cellular response to ionizing radiation and to other tumorigenic events; therefore, loss of this protein increases the tumor burden in mice.

  9. SWI (show SMARCA1 Proteins)/SNF (show SNRPA Proteins) functions independently of HMGN1

  10. Five serine residues, i.e., Ser6, Ser7, Ser85, Ser88, and Ser98, in HMGN1 can be phosphorylated by the kinase in vitro, and Ser6, Ser7, and Ser85 were new sites among these five sites.

HMGN1 Protein Profile

Protein Summary

The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMG17, the encoded protein may help maintain an open chromatin configuration around transcribable genes.

Gene names and symbols associated with HMGN1

  • high mobility group nucleosome binding domain 1 (hmgn1-b)
  • high mobility group nucleosome binding domain 1 (hmgn1)
  • high-mobility group nucleosome binding domain 1 (HMGN1)
  • high mobility group nucleosomal binding domain 1 (Hmgn1)
  • high mobility group nucleosome binding domain 1 (HMGN1)
  • high mobility group nucleosome binding domain 1 (Hmgn1)
  • high-mobility group nucleosome binding domain 1 (LOC100350031)
  • HMG-14 protein
  • HMG14 protein
  • hmgn1 protein
  • hmgn1b protein

Protein level used designations for HMGN1

high-mobility group nucleosome binding domain 1 b , high-mobility group nucleosome binding domain 1 , non-histone chromosomal protein HMG-14 , high mobility group nucleosome-binding domain-containing protein 1 , high mobility group protein 14 , high-mobility group nucleosome-binding domain-containing protein 1 , HMG-14 protein , non-histone chromosomal protein HMG-14B , high-mobility group (nonhistone chromosomal) protein 14 , high-mobility group nucleosome binding 1 , nonhistone chromosomal protein HMG-14

GENE ID SPECIES
380456 Xenopus laevis
394660 Xenopus (Silurana) tropicalis
100137463 Papio anubis
15312 Mus musculus
395999 Gallus gallus
3150 Homo sapiens
785479 Bos taurus
360704 Rattus norvegicus
100328653 Oryctolagus cuniculus
100725547 Cavia porcellus
614915 Bos taurus
100350031 Oryctolagus cuniculus
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