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High Mobility Group Nucleosome Binding Domain 5 (HMGN5) ELISA Kits

HMGN5 encodes a nuclear protein with similarities to the high mobility group proteins, HMG14 and HMG17, which suggests that this protein may function as a nucleosomal binding and transcriptional activating protein. Additionally we are shipping HMGN5 Antibodies (33) and HMGN5 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human HMGN5 HMGN5 79366 P82970
Anti-Rat HMGN5 HMGN5 681284 B4F777
Anti-Mouse HMGN5 HMGN5 50887 Q9JL35
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More ELISA Kits for HMGN5 Interaction Partners

Human High Mobility Group Nucleosome Binding Domain 5 (HMGN5) interaction partners

  1. NSBP1 was highly expressed in NSCLC cells. NSBP1 siRNA knockdown suppressed NSCLC cell proliferation and invasion. miR326 has a putative binding site in the NSBP1 3'UTR (show UTS2R ELISA Kits). NSBP1 overexpression abolished miR326 inhibition of cyclin B1 (show CCNB1 ELISA Kits) and MMP9 (show MMP9 ELISA Kits) expression.

  2. HMGN5 overexpression is correlated with advanced pathological grade and poorer prognosis in meningiomas

  3. Decreased miR (show MLXIP ELISA Kits)-340 expression may contribute to the development and progression of prostate cancer through a mechanism that involves HMGN5.

  4. Our data first time identified miR (show MLXIP ELISA Kits)-186 as the upstream regulator of NSBP1

  5. High HMGN5 expression is associated with urothelial bladder cancer.

  6. HMGN5 is an oncogene (show RAB1A ELISA Kits) and plays an important role in prostate cancer tumorigenesis and progression. the level of HMGN5 may be used as a biomarker to predict the patients that would benefit from gemcitabine treatment.

  7. HMGN5 plays an oncogenic role in human breast cancer by inhibiting cell proliferation and invasion, and activating apoptosis, which could be exploited as a target for therapy in human breast cancer.

  8. HMGN5 knockdown sensitizes prostate cancer cells to ionizing radiation

  9. HMGN5 plays oncogenic role in osteosarcoma by promoting cell proliferation and invasion, and could be exploited as a target for therapy in osteosarcoma.

  10. HMGN5 is a critical factor in the development of chemoresistance through regulating autophagy, and it offers a novel target for improving osteosarcoma therapy.

Mouse (Murine) High Mobility Group Nucleosome Binding Domain 5 (HMGN5) interaction partners

  1. Mice overexpressing HMGN5, either globally or only in the heart, are normal at birth but develop hypertrophic heart with large cardiomyoctyes, deformed nuclei and disrupted lamina, and die of cardiac malfunction.

  2. HMGN5 overexpression induces neurite outgrowth.

  3. functional loss of HMGN5 leads to changes in transcription of Gpx6 (show GPX7 ELISA Kits) and Hk1 (show HK1 ELISA Kits) that alter glutathione metabolism.

  4. Phenotypic analysis of Hmgn1 (show HMGN1 ELISA Kits)(tm1/tm1 (show TPM2 ELISA Kits)), Hmgn3 (show HMGN3 ELISA Kits)(tm1/tm1 (show TPM2 ELISA Kits)), and Hmgn5(tm1/tm1 (show TPM2 ELISA Kits)) mice and their wild type littermates with a battery of standardized tests uncovered variant-specific abnormalities.

  5. Downregulation of NSBP1 reduced the cancer growth rate, whereas tumourigenicity was not influenced.

  6. NSBP1 is an architectural protein that binds preferentially to euchromatin and modulates the fidelity of the cellular transcription profile by counteracting the chromatin-condensing activity of linker histones.

HMGN5 Antigen Profile

Antigen Summary

This gene encodes a nuclear protein with similarities to the high mobility group proteins, HMG14 and HMG17, which suggests that this protein may function as a nucleosomal binding and transcriptional activating protein.

Gene names and symbols associated with HMGN5

  • high mobility group nucleosome binding domain 5 (HMGN5) antibody
  • high mobility group nucleosome binding domain 5B (Hmgn5b) antibody
  • high-mobility group nucleosome binding domain 5 (Hmgn5) antibody
  • GARP45 antibody
  • Hmgn5 antibody
  • Hmgn5l1 antibody
  • NBP-45 antibody
  • Nsbp1 antibody

Protein level used designations for HMGN5

high mobility group nucleosome-binding domain-containing protein 5 , high-mobility group nucleosome binding domain 5 , nucleosomal binding protein 1 , nucleosome-binding protein 1 , high-mobility group nucleosome binding domain 5-like 1 , nucleosome binding protein 1 , nucleosome binding protein 45

GENE ID SPECIES
79366 Homo sapiens
681284 Rattus norvegicus
50887 Mus musculus
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