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Histamine N-Methyltransferase Proteins (HNMT)

In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. Additionally we are shipping HNMT Antibodies (72) and HNMT Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HNMT 3176 P50135
HNMT 140483 Q91VF2
Rat HNMT HNMT 81676 Q01984
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Top HNMT Proteins at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human GST tag 10 μg Log in to see 16 Days
$250.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
Yeast Tetraodon nigroviridis His tag   1 mg Log in to see 56 to 66 Days
$2,768.33
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$2,772.00
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,772.00
Details
Yeast Guinea Pig His tag   1 mg Log in to see 56 to 66 Days
$2,772.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,772.00
Details

HNMT Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Top referenced HNMT Proteins

  1. Human HNMT Protein expressed in Escherichia coli (E. coli) - ABIN2005438 : Yan, Galinsky, Bernstein, Liggett, Weinshilboum: Histamine N-methyltransferase pharmacogenetics: association of a common functional polymorphism with asthma. in Pharmacogenetics 2000 (PubMed)
    Show all 3 references for ABIN2005438

More Proteins for Histamine N-Methyltransferase (HNMT) Interaction Partners

Human Histamine N-Methyltransferase (HNMT) interaction partners

  1. HNMT is identified as a novel gene responsible for intellectual disability. The consequences of the identified missense mutations on the protein function are discussed.

  2. HRH1 (show DHX8 Proteins)-17 TT and HNMT-1639 TT genotypes were associated with the allergic asthma phenotype among African-American children and that the ABP (show ABP1 Proteins) 4107 GG genotype was associated with nonallergic asthma among white children.

  3. results suggest that the heterozygous Thr/Ile genotype at the HNMT-Thr105Ile locus and the minor Ile105 allele protect against Parkinson's disease and schizophrenia in Han Chinese.

  4. The polymorphisms of HNMT and HRH3 (show HRH3 Proteins) were irrelevant with breast cancer in the present study.

  5. The A939G HNMT polymorphism is associated with autoimmune MG, while no association with C314T SNP was found.

  6. The results of this study indicated that Histamine N-methyltransferase Thr105Ile polymorphism is associated Parkinson's disease.

  7. Lack of the association of HNMT Thr105Ile functional polymorphism with Alzheimer's disease is found.

  8. our results suggest that, despite the possible role of histamine in the inflammatory processes related with the pathogenesis of MS, HNMT polymorphism is not related with the risk for MS in Caucasian Spanish people

  9. This study do not support the HNMT Thr105Ile variant as a factor in disease development or a genetic link between the disorders.

  10. identification of several novel HNMT polymorphisms, identification of the HNMT core promoter

Mouse (Murine) Histamine N-Methyltransferase (HNMT) interaction partners

  1. Genomic structure of the rat and mouse histamine N-methyltransferase gene

  2. decreasing expression over the time course of the skin pathological changes in MRL/lpr (show FAS Proteins) mice

HNMT Protein Profile

Protein Summary

In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.

Gene names and symbols associated with HNMT

  • histamine N-methyltransferase (HNMT)
  • histamine N-methyltransferase (hnmt)
  • Histamine N-methyltransferase (hnmt)
  • histamine N-methyltransferase (LOC100228106)
  • histamine N-methyltransferase (LOC100347399)
  • histamine N-methyltransferase (Hnmt)
  • 1500031F01Rik protein
  • AI788969 protein
  • HMT protein
  • hnmt protein
  • HNMT-S1 protein
  • HNMT-S2 protein
  • zgc:100917 protein

Protein level used designations for HNMT

histamine N-methyltransferase , HMT , Histamine N-methyltransferase

GENE ID SPECIES
424298 Gallus gallus
476133 Canis lupus familiaris
641310 Ovis aries
706713 Macaca mulatta
742204 Pan troglodytes
779808 Xenopus (Silurana) tropicalis
100196123 Salmo salar
100228106 Taeniopygia guttata
100347399 Oryctolagus cuniculus
100528906 Ictalurus punctatus
3176 Homo sapiens
140483 Mus musculus
81676 Rattus norvegicus
613413 Bos taurus
100135537 Cavia porcellus
100174618 Pongo abelii
445242 Danio rerio
Selected quality suppliers for HNMT Proteins (HNMT)
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