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anti-Histamine Receptor H2 (HRH2) Antibodies

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HRH2 25461 P25102
HRH2 3274 P25021
HRH2 15466  
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Top anti-HRH2 Antibodies at antibodies-online.com

Showing 10 out of 62 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of HRH2 Antibody (Center) in Uterus cell line lysates (35ug/lane). This demonstrates the HRH2 antibody detected the HRH2 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Mouse Rabbit Un-conjugated IF, IHC, WB Western blot analysis of rat basophilic leukemia cells (RBL) (lanes 1 and 3) and rat brain lysates (lanes 2 and 4): 1, 2. Anti-Rat H2 Histamine Receptor (extracellular) antibody, (1:200). 3, 4. Anti- Rat H2 Histamine Receptor (extracellular) antibody, preincubated with the control peptide antigen. Expression of H2 Histamine Receptor in rat stomach Immunohistochemical staining of paraffin embedded section of rat stomach using Anti-Rat H2 Histamine Receptor (extracellular) antibody, (1:100). H2R (brown staining) is expressed in parietal cells (arrows) of the gastric glands. Hematoxilin is used as the counterstain. 50 μL Log in to see 10 to 11 Days
$678.57
Details
Human Goat Un-conjugated IHC, ELISA, WB   100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated ICC, FACS, IF, IHC (p), IHC, WB WB Image Histamine H2 Receptor antibody [N1], N-term detects HRH2 protein by Western blot analysis. A. 30 µg U87-MG whole cell lysate/extract B. 30 µg SK-N-SH whole cell lysate/extract 10 % SDS-PAGE Histamine H2 Receptor antibody [N1], N-term , dilution: 1:1000 IHC-P Image Immunohistochemical analysis of paraffin-embedded H520 xenograft, using Histamine H2 Receptor, antibody at 1:100 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IHC (p) Anti-HRH2 / Histamine H2 Receptor antibody  ABIN1048959 IHC staining of human stomach, parietal cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p) Anti-HRH2 / Histamine H2 Receptor antibody  ABIN1048958 IHC staining of human stomach, parietal cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemical staining of Stomach (Parietal cells) using anti- HRH2 antibody ABIN122537 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemical staining of Stomach (Parietal cells) using anti- HRH2 antibody ABIN122536 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IC, IF, WB Immunofluorescent analysis of Histamine H2 Receptor staining in COLO205 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of Histamine H2 Receptor expression in HEK293T (A), COLO205 (B), NIH3T3 (C), H9C2 (D) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated IF, ELISA 100 μL Log in to see 8 to 10 Days
$478.50
Details

HRH2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-HRH2 Antibodies

  1. Human Polyclonal HRH2 Primary Antibody for EIA, WB - ABIN952742 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 3 references for ABIN952742

  2. Human Polyclonal HRH2 Primary Antibody for IHC, ELISA - ABIN185463 : Nakane, Sonobe, Watanabe, Nakano: Histamine: its novel role as an endogenous regulator of Con A-dependent T cell proliferation. in Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2004 (PubMed)
    Show all 2 references for ABIN185463

  3. Mouse (Murine) Polyclonal HRH2 Primary Antibody for IF, IHC - ABIN1742058 : Kobayashi, Tonai, Ishihara, Koga, Okabe, Watanabe: Abnormal functional and morphological regulation of the gastric mucosa in histamine H2 receptor-deficient mice. in The Journal of clinical investigation 2000 (PubMed)
    Show all 2 references for ABIN1742058

More Antibodies against HRH2 Interaction Partners

Rhesus Monkey Histamine Receptor H2 (HRH2) interaction partners

  1. Histamine H2 receptor mRNA is localized in cone inner segments from retina.

Human Histamine Receptor H2 (HRH2) interaction partners

  1. High constitutive Akt2 (show AKT2 Antibodies) activity in U937 promonocytes: effective reduction of Akt2 (show AKT2 Antibodies) phosphorylation by the histamine H2-receptor and the beta2-adrenergic receptor (show ADRB2 Antibodies)

  2. Lack of Association between rs2067474 Polymorphism in Histamine Receptor H2 Gene and Breast Cancer in Chinese Han Population

  3. But carriers of one or three copies of HRH1 (show DHX8 Antibodies) (5% of individuals), HRH2 (show DHX15 Antibodies) (1.1%) and HRH4 (show HRH4 Antibodies) genes (0.9%) were also identified.

  4. The inhibitory effects of histamine on reactive oxygen species production in whole blood phagocytes are caused by H2R rather than H4R (show HRH4 Antibodies) histamine receptors.

  5. HR signaling through cyclic AMP (show APRT Antibodies) and exchange protein directly activated by cyclic AMP (show APRT Antibodies) was required for the histamine effect on LPS (show IRF6 Antibodies)-induced monocyte-derived dendritic cells responses

  6. rs2607474 GG homozygote confers a significantly increased risk for age- and inflammation-related DAPK (show DAPK1 Antibodies) and CDH1 (show CDH1 Antibodies) methylation in gastric epithelium.

  7. HR2 (show MFN1 Antibodies) receptor is involved in histamine-induced GDF-15 (show GDF15 Antibodies) expression.

  8. The results suggest that HRH2 (show DHX15 Antibodies) -1018 GG homozygote is a risk factor for the severity of gastric mucosal atrophy under the influence of H. pylori infection, especially in older subjects.

  9. 1018 GG homozygosity of HRH2 (show DHX15 Antibodies) may be associated with the severity of gastric mucosal atrophy

  10. GRK2 (show ADRBK1 Antibodies) induces desensitization of H2R through a phosphorylation-independent and RGS (show PITX2 Antibodies)-dependent mechanism

Mouse (Murine) Histamine Receptor H2 (HRH2) interaction partners

  1. Ability of probiotic L. reuteri to suppress colitis depends on the presence of a bacterial histidine decarboxylase (show HDC Antibodies) gene(s) in the intestinal microbiome, consumption of a histidine-containing diet, and signaling via the histamine H2 receptor (H2R).

  2. required for IL-6 (show IL6 Antibodies) and IL-17 (show IL17A Antibodies) mucosal responses to intestinal histamine-secreting microbes

  3. histamine receptor H1 (show HRH1 Antibodies) and histamine receptor H2 reciprocally regulate inflammation in the ligation-induced arteriosclerosis

  4. Data show that experimental allergic encephalomyelitis (EAE) severity and in histamine H2 receptor (H2RKO) mice expressing H2R exclusively in T cells become equal to those in wild-type B6 mice only when pertussis toxin is used to elicit disease.

  5. H2R activation exaggerates myocardial I/R injury by promoting myocardial mitochondrial dysfunction and by increasing cardiac vascular endothelial permeability.

  6. Data suggest histamine stimulates proliferation of Leydig tumor cells via activation of HRH2 and a transient increase in intracellular cAMP levels. Normal/immature Leydig cells and progenitor Leydig cells exhibit very low levels of HDC (show HDC Antibodies) expression.

  7. Histamine reduced the alpha-CD3 (show CD3E Antibodies)-induced interferon-gamma (IFN-gamma (show IFNG Antibodies)) production of CD4 (show CD4 Antibodies)+ cells via the histamine H-receptor.

  8. A previously unidentified role for H2R establishes a synergy between endogenous histamine and interleukin (IL)-4 (show IL4 Antibodies) that supports eosinophilic recruitment to the lung.

  9. HR2 (show MFN1 Antibodies) immunoreactivity was observed on the processes and cell bodies of the primary glial cells of the mammalian retina, the Muller cells.

  10. decreasing expression on the mast cells within skin lesions of MRL/lpr (show FAS Antibodies) mice

HRH2 Antigen Profile

Protein Summary

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with HRH2

  • histamine receptor H2 (HRH2) antibody
  • uncharacterized LOC521257 (LOC521257) antibody
  • histamine receptor H2 (hrh2) antibody
  • histamine receptor H2 (LOC100338726) antibody
  • histamine receptor H 2 (Hrh2) antibody
  • histamine receptor H2 (Hrh2) antibody
  • H2R antibody
  • HH2R antibody
  • HRH2 antibody

Protein level used designations for HRH2

histamine receptor H2 , histamine H2 receptor , HH2R , gastric receptor I , gastric receptor 1 , H2R , histamine receptor subtype H2 , histamine receptor H 2

GENE ID SPECIES
427635 Gallus gallus
443190 Ovis aries
521257 Bos taurus
695226 Macaca mulatta
735303 Danio rerio
100338726 Oryctolagus cuniculus
25461 Rattus norvegicus
3274 Homo sapiens
15466 Mus musculus
403812 Canis lupus familiaris
100729734 Cavia porcellus
100135540 Cavia porcellus
471750 Pan troglodytes
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