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Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Additionally we are shipping HRH2 Antibodies (122) and HRH2 Proteins (4) and many more products for this protein.
Pharmacological or genetic modulations of H2 and H4 HRs (H2R and H4R (show HRH4 ELISA Kits)) not only suppressed gefitinib-induced cytostasis and differentiation of AML (show RUNX1 ELISA Kits) cells but also blocked EGFR (show EGFR ELISA Kits) and ERK1/2 (show MAPK1/3 ELISA Kits) inhibition in MDA-MB-231 cells
The T allele of rs3787429 exhibited protective effect against CHF under the dominant and additive models , while, for SNPs in HRH2 (show DHX15 ELISA Kits), DAO (show ABP1 ELISA Kits), and HNMT (show HNMT ELISA Kits), no significant associations were observed in the present study
High constitutive Akt2 (show AKT2 ELISA Kits) activity in U937 promonocytes: effective reduction of Akt2 (show AKT2 ELISA Kits) phosphorylation by the histamine H2-receptor and the beta2-adrenergic receptor (show ADRB2 ELISA Kits)
Lack of Association between rs2067474 Polymorphism in Histamine Receptor H2 Gene and Breast Cancer in Chinese Han Population
But carriers of one or three copies of HRH1 (show DHX8 ELISA Kits) (5% of individuals), HRH2 (show DHX15 ELISA Kits) (1.1%) and HRH4 (show HRH4 ELISA Kits) genes (0.9%) were also identified.
The inhibitory effects of histamine on reactive oxygen species production in whole blood phagocytes are caused by H2R rather than H4R (show HRH4 ELISA Kits) histamine receptors.
HR signaling through cyclic AMP (show APRT ELISA Kits) and exchange protein directly activated by cyclic AMP (show APRT ELISA Kits) was required for the histamine effect on LPS (show IRF6 ELISA Kits)-induced monocyte-derived dendritic cells responses
rs2607474 GG homozygote confers a significantly increased risk for age- and inflammation-related DAPK (show DAPK1 ELISA Kits) and CDH1 (show CDH1 ELISA Kits) methylation in gastric epithelium.
HR2 (show MFN1 ELISA Kits) receptor is involved in histamine-induced GDF-15 (show GDF15 ELISA Kits) expression.
The results suggest that HRH2 (show DHX15 ELISA Kits) -1018 GG homozygote is a risk factor for the severity of gastric mucosal atrophy under the influence of H. pylori infection, especially in older subjects.
Ability of probiotic L. reuteri to suppress colitis depends on the presence of a bacterial histidine decarboxylase (show HDC ELISA Kits) gene(s) in the intestinal microbiome, consumption of a histidine-containing diet, and signaling via the histamine H2 receptor (H2R).
required for IL-6 (show IL6 ELISA Kits) and IL-17 (show IL17A ELISA Kits) mucosal responses to intestinal histamine-secreting microbes
histamine receptor H1 (show HRH1 ELISA Kits) and histamine receptor H2 reciprocally regulate inflammation in the ligation-induced arteriosclerosis
Data show that experimental allergic encephalomyelitis (EAE) severity and in histamine H2 receptor (H2RKO) mice expressing H2R exclusively in T cells become equal to those in wild-type B6 mice only when pertussis toxin is used to elicit disease.
H2R activation exaggerates myocardial I/R injury by promoting myocardial mitochondrial dysfunction and by increasing cardiac vascular endothelial permeability.
Data suggest histamine stimulates proliferation of Leydig tumor cells via activation of HRH2 and a transient increase in intracellular cAMP levels. Normal/immature Leydig cells and progenitor Leydig cells exhibit very low levels of HDC (show HDC ELISA Kits) expression.
Histamine reduced the alpha-CD3 (show CD3E ELISA Kits)-induced interferon-gamma (IFN-gamma (show IFNG ELISA Kits)) production of CD4 (show CD4 ELISA Kits)+ cells via the histamine H-receptor.
A previously unidentified role for H2R establishes a synergy between endogenous histamine and interleukin (IL)-4 (show IL4 ELISA Kits) that supports eosinophilic recruitment to the lung.
HR2 (show MFN1 ELISA Kits) immunoreactivity was observed on the processes and cell bodies of the primary glial cells of the mammalian retina, the Muller cells.
decreasing expression on the mast cells within skin lesions of MRL/lpr (show FAS ELISA Kits) mice
Histamine H2 receptor mRNA is localized in cone inner segments from retina.
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, gastric receptor 1
, gastric receptor I
, histamine H2 receptor
, histamine receptor subtype H2
, histamine receptor H2