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Histidine Decarboxylase Proteins (HDC)

HDC encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Additionally we are shipping Histidine Decarboxylase Antibodies (49) and Histidine Decarboxylase Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HDC 380629  
HDC 3067 P19113
HDC 24443  
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Top Histidine Decarboxylase Proteins at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 11 to 13 Days
$774.40
Details
Yeast Lactobacillus sp. His tag   1 mg Log in to see 56 to 66 Days
$2,115.67
Details
Yeast Morganella morganii His tag   1 mg Log in to see 56 to 66 Days
$3,036.00
Details
Yeast Bacteria His tag   1 mg Log in to see 56 to 66 Days
$3,036.00
Details
Yeast Acinetobacter baumannii His tag   1 mg Log in to see 56 to 66 Days
$3,054.33
Details
Yeast Vibrio harveyi His tag   1 mg Log in to see 56 to 66 Days
$3,063.50
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,903.17
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 11 to 13 Days
$774.40
Details

HDC Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,

Rat (Rattus) ,

More Proteins for Histidine Decarboxylase (HDC) Interaction Partners

Fruit Fly (Drosophila melanogaster) Histidine Decarboxylase (HDC) interaction partners

  1. genes encoding for proteins involved in histamine signaling [histidine decarboxylase (hdc), histamine-gated chloride channel (show CLCA1 Proteins) subunit 1 (hisCl1), ora transientless (ort)] cause abnormal temperature preferences

Zebrafish Histidine Decarboxylase (HDC) interaction partners

  1. Ethanol upregulates histidine decarboxylase expression in neural brain networks.

Mouse (Murine) Histidine Decarboxylase (HDC) interaction partners

  1. Lack of endogenous histamine in NOD HDC(-/-) mice decreased the incidence of diabetes in relation to their wild-type counterpart.

  2. the structure and function of the retina in mice that lacked expression of the rate limiting enzyme in the formation of histamine, histidine decarboxylase (Hdc-/- mouse), were investigated.

  3. SDS (show SDS Proteins) induces itch through increased production of epidermal histamine, which results from an increase in the gene expression and post-translation processing of L-histidine decarboxylase.

  4. HDC, whose expression is remarkably downregulated during the first few days after birth in dermal cells of mice, plays essential roles in the hair-inducing ability of newborn mouse dermal cells

  5. An increased expression of H3 receptors in HDC KO mice without any changes in the spontaneous firing of "histaminergic" neurons without histamine and their responses to the H3 receptor agonist (R)-alpha-methylhistamine.

  6. Histidine decarboxylase was found at comparably high levels in mouse striatum.

  7. There was no difference in the levels of vascular endothelial growth factor between HDC-/- or wild-type mice, either in the lung or in bronchoalveolar-lavage cells.

  8. HDC-/- mice showed reduced severity of K/BxN serum-induced arthritis.

  9. in 12 day old embryonic stem cells histidine decarboxylase was confined to peripheral cells and small clusters of cells, inner cells were usually negative for it

  10. Metabolic phenotype of mice lacking histamine due to targeted disruption of histidine decarboxylase. Characterized by visceral adiposity, increased of brown adipose tissue, impaired glucose tolerance, hyperinsulinemia, and hyperleptinemia.

Human Histidine Decarboxylase (HDC) interaction partners

  1. The findings indicate that polymorphisms of HDC gene were significantly associated with breast cancer in Chinese Han population and may be novel diagnostic or therapeutic targets for breast cancer.

  2. HDC rs17740607 polymorphism is at least a partial loss-of-function variant and acts as a protective factor against chronic heart failure

  3. Investigated variation across the HDC (histidine decarboxylase) gene for association with Tourette Syndrome.

  4. HDC production in the stomach is associated with bile acid exposure and its related transcriptional regulation network of FXR (show NR1H4 Proteins), SHP (show LAMC1 Proteins), and CDX1 (show CDX1 Proteins).

  5. Data indicate that histidine decarboxylase (HDC) is expressed by neutrophils.

  6. Structural study reveals that Ser (show SIGLEC1 Proteins)-354 determines substrate specificity on human histidine decarboxylase.

  7. crystal of histidine decarboxylase belonged to space group C2, with unit-cell parameters a = 215.16, b = 112.72, c = 171.39 A, beta = 110.3 degrees

  8. It was shown that for serum and urine, HDC levels achieved sensitivities and specificities compatible to or even greater than those of established biomarkers for the diagnosis of intestinal mucosal injury in patients with acute intestinal obstruction.

  9. The novel concept that an autocrine loop, consisting of enhanced histamine synthesis by histidine decarboxylase, sustains cholangiocarcinoma growth is proposed.

  10. Variants in the HDC gene may play little or no role in Tourette Syndrome susceptibility in Chinese Han population.

Histidine Decarboxylase (HDC) Protein Profile

Protein Summary

This gene encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion,inflamation, and smooth muscle tone.

Gene names and symbols associated with Histidine Decarboxylase Proteins (HDC)

  • Histidine decarboxylase (Hdc)
  • histidine decarboxylase (HDC)
  • histidine decarboxylase (hdc)
  • histidine decarboxylase (Desac_2880)
  • histidine decarboxylase (LOC100313635)
  • histidine decarboxylase (LOC100533309)
  • headcase homolog (Drosophila) (Heca)
  • histidine decarboxylase (Hdc)
  • 4732480P20 protein
  • anon-WO0140519.259 protein
  • AW108189 protein
  • CG3454 protein
  • Dmel\\CG3454 protein
  • Gm869 protein
  • HDC protein
  • Hdc-a protein
  • Hdc-c protein
  • Hdc-e protein
  • Hdc-s protein
  • HDCL protein
  • JK910 protein
  • LOC100313635 protein

Protein level used designations for Histidine Decarboxylase Proteins (HDC)

CG3454-PA , CG3454-PB , CG3454-PC , Hdc-PA , Hdc-PB , Hdc-PC , histidine decarboxylase , histidine-decarboxylase , histidine decarboxylase-like , headcase protein homolog , L-histidine decarboxylase

GENE ID SPECIES
36076 Drosophila melanogaster
453425 Pan troglodytes
548615 Strongylocentrotus purpuratus
715287 Macaca mulatta
793609 Danio rerio
10438116 Desulfobacca acetoxidans DSM 11109
100313635 Saccoglossus kowalevskii
100407107 Callithrix jacchus
100435706 Pongo abelii
100533309 Aplysia californica
100583943 Nomascus leucogenys
380629 Mus musculus
3067 Homo sapiens
487551 Canis lupus familiaris
15186 Mus musculus
24443 Rattus norvegicus
100719978 Cavia porcellus
415454 Gallus gallus
100156724 Sus scrofa
515950 Bos taurus
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