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Histidyl TRNA Synthetase Proteins (HARS)

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Additionally we are shipping Histidyl TRNA Synthetase Antibodies (75) and Histidyl TRNA Synthetase Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HARS 3035 P12081
HARS 15115 Q61035
Rat HARS HARS 307492  
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Top Histidyl TRNA Synthetase Proteins at antibodies-online.com

Showing 10 out of 23 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Log in to see 3 to 4 Days
$5,769.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$364.64
Details
HOST_Sf-9 cells Human His tag   1 mg Log in to see 3 to 4 Days
$4,339.50
Details
HOST_Sf-9 cells Human Un-conjugated   5 μg Log in to see 6 to 11 Days
$142.86
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 6 to 11 Days
$142.86
Details
HOST_Baculovirus/Sf9 Human His tag   5 μg Log in to see 6 to 8 Days
$168.30
Details

HARS Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine)

Top referenced Histidyl TRNA Synthetase Proteins

  1. Human HARS Protein expressed in Escherichia coli (E. coli) - ABIN667221 : OHanlon, Miller: Genomic organization, transcriptional mapping, and evolutionary implications of the human bi-directional histidyl-tRNA synthetase locus (HARS/HARSL). in Biochemical and biophysical research communications 2002 (PubMed)
    Show all 2 references for ABIN667221

More Proteins for Histidyl TRNA Synthetase (HARS) Interaction Partners

Human Histidyl TRNA Synthetase (HARS) interaction partners

  1. Loss of function mutations in histidyl-tRNA synthetase cause a spectrum of inherited peripheral neuropathies

  2. Data suggest that by comparing human and trypanosomatid histidyl-tRNA synthetases (HisRS) may provide opportunities for developing specific inhibitors of Trypanosoma brucei HisRS.

  3. Secreted histidyl-tRNA synthetase splice variants elaborate major epitopes for autoantibodies in inflammatory myositis.

  4. Data indicate that higher anti-Jo1 levels were associated with disease severity in antisynthetase syndrome (ASS (show ASS1 Proteins)) patients.

  5. Findings suggest that histidyl-tRNA synthetase (HARS) is associated with axonal peripheral neuropathy.

  6. Study identified sequence variants in the known disease-causing genes SLC6A3 (show SLC6A3 Proteins) and FLVCR1 (show FLVCR1 Proteins), and present evidence to strongly support the pathogenicity of variants identified in TUBGCP6, BRAT1 (show C7orf27 Proteins), SNIP1 (show SNIP1 Proteins), CRADD (show CRADD Proteins), and HARS.

  7. genomic organization of the HARS locus and mapping of transcripts originating from a bi-directional promoter controlling the differential expression of these gene

  8. Demonstrating histidyl-tRNA synthetase (Jo-1)-specific T cell responses represents a key step in establishing the hypothesis that Jo-1 drives T cell-mediated autoimmunity in Jo-1+ polymyositis.

  9. the TSG101 (show TSG101 Proteins) interaction with HRS is a crucial step in endocytic down-regulation of mitogenic signaling and this interaction may have a role in linking the functions of early and late endosomes

  10. A proteolytically sensitive conformation of HisRS exists in the lung, the target tissue associated with this autoantibody response.

Mouse (Murine) Histidyl TRNA Synthetase (HARS) interaction partners

  1. AA 60-90 of HRS were absolutely required for in vitro as well as in vivo signaling via MyD88 (show MYD88 Proteins)-dependent TLR pathways to case myositis.

Histidyl TRNA Synthetase (HARS) Protein Profile

Protein Summary

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with HARS

  • histidyl-tRNA synthetase (HARS)
  • histidyl-tRNA synthetase (Hars)
  • Dnd1 protein
  • HARSL protein
  • HRS protein
  • MMHRS protein
  • USH3B protein

Protein level used designations for HARS

HisRS , histidine translase , histidine--tRNA ligase, cytoplasmic , hisRS , histidine tRNA ligase , histidyl-tRNA synthetase, cytoplasmic , dead end homolog 1 , Histidyl-tRNA synthetase, cytoplasmic

GENE ID SPECIES
478034 Canis lupus familiaris
3035 Homo sapiens
15115 Mus musculus
307492 Rattus norvegicus
510937 Bos taurus
100173931 Pongo abelii
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