Histone Cluster 1, H3a Proteins (HIST1H3A)

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Additionally we are shipping Histone Cluster 1, H3a Antibodies (56) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HIST1H3A 8350 P68431
Mouse HIST1H3A HIST1H3A 360198 P68433
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Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 20 to 21 Days
$437.80
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HIST1H3A Proteins by Origin and Source

Origin Expressed in
Human

Top referenced Histone Cluster 1, H3a Proteins

  1. Human HIST1H3A Protein expressed in Escherichia coli (E. coli) - ABIN2004139 : Alexander, Periman, Hanson, Mahler: Mosaic organization of a mitochondrial gene: evidence from double mutants in the cytochrome b region of Saccharomyces cerevisiae. in Cell 1980 (PubMed)
    Show all 4 references for 2004139

More Proteins for Histone Cluster 1, H3a (HIST1H3A) Interaction Partners

Human Histone Cluster 1, H3a (HIST1H3A) interaction partners

  1. Approximately 30% of pediatric high grade gliomas (pedHGG) including GBM and DIPG harbor a lysine 27 mutation (K27M) in histone 3.3 (H3.3) which is correlated with poor outcome and was shown to influence EZH2 (show EZH2 Proteins) function.

  2. H3F3A (show H3F3A Proteins) K27M mutation in adult cerebellar HGG is not rare.

  3. Data show that lysyl oxidase-like 2 (LOXL2 (show LOXL2 Proteins)) is a histone modifier enzyme that removes trimethylated lysine 4 (K4) in histone H3 (show HIST3H3 Proteins) (H3K4me3) through an amino-oxidase reaction.

  4. Histone H3 (show HIST3H3 Proteins) lysine 9 (H3K9) acetylation was most prevalent when the Dbf4 (show DBF4 Proteins) transcription level was highest whereas the H3K9me3 level was greatest during and just after replication.

  5. SPOP-containing complex regulates SETD2 stability and H3K36me3-coupled alternative splicing.

  6. Data suggest that binding of helical tail of histone 3 (H3) with PHD ('plant homeodomain') fingers of BAZ2A or BAZ2B (bromodomain adjacent to zinc finger domain 2A or 2B) requires molecular recognition of secondary structure motifs within H3 tail and could represent an additional layer of regulation in epigenetic processes.

  7. The results demonstrate a novel mechanism by which Kdm4d (show KDM4D Proteins) regulates DNA replication by reducing the H3K9me3 level to facilitate formation of preinitiation complex.

  8. Histone H3 (show HIST3H3 Proteins) modifications caused by traffic-derived airborne particulate matter exposures in leukocytes

  9. A key role of persistent histone H3 (show HIST3H3 Proteins) serine 10 or serine 28 phosphorylation in chemical carcinogenesis through regulating gene transcription of DNA damage response genes

  10. AS1eRNA-driven DNA looping and activating histone modifications promote the expression of DHRS4 (show DHRS4 Proteins)-AS1 (show PTGDR Proteins) to economically control the DHRS4 (show DHRS4 Proteins) gene cluster.

Mouse (Murine) Histone Cluster 1, H3a (HIST1H3A) interaction partners

  1. Hemi-methylated DNA opens a closed conformation of UHRF1 (show UHRF1 Proteins) to facilitate its H3 histone (show HIST1H3B Proteins) recognition.

  2. Findings show that CCL2 (show CCL2 Proteins) and CCL3 (show CCL3 Proteins) are upregulated in the injured peripheral nerve through epigenetic histone modification in infiltrating immune cells such as macrophages.

  3. This result suggests that the incorporation of H3.1 has a detrimental effect on the process of genome remodeling and contributes to the low success rate of somatic nuclear cloning.

Histone Cluster 1, H3a (HIST1H3A) Protein Profile

Protein Summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails\; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Gene names and symbols associated with HIST1H3A

  • histone cluster 1, H3a (HIST1H3A)
  • histone cluster 1, H3a (Hist1h3a)
  • H3/A protein
  • H3FA protein

Protein level used designations for HIST1H3A

H3 histone family, member A , histone 1, H3a , histone H3.1 , histone H3/a

GENE ID SPECIES
8350 Homo sapiens
360198 Mus musculus
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