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Histone Deacetylase 4 Proteins (HDAC4)

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Additionally we are shipping HDAC4 Antibodies (253) and HDAC4 Kits (13) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HDAC4 9759 P56524
HDAC4 208727 Q6NZM9
HDAC4 363287 Q99P99
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Top HDAC4 Proteins at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Baculovirus infected Insect Cells Human Un-conjugated 100 μg Log in to see 16 Days
$437.80
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Baculovirus Human GST tag HDAC4 activity assay. Recombinant HDAC4 activity measured using a fluorescent HDAC assay. HDAC4 protein gel. HDAC4 run on an SDS-PAGE gel and stained with Coomassie blue. 10 μg Log in to see 1 to 2 Days
$460.83
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated HDAC4 protein gel. HDAC4 run on an SDS-PAGE gel and stained with Coomassie blue. 100 μg Log in to see 1 to 2 Days
$460.83
Details
HOST_Sf-9 cells Human GST tag   50 μg Log in to see 3 to 4 Days
$231.00
Details
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$322.08
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details

HDAC4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
,
Mouse (Murine)

Rat (Rattus)

Top referenced HDAC4 Proteins

  1. Human HDAC4 Protein expressed in Wheat germ - ABIN1306452 : Isaacs, Antony, Dalrymple, Brennen, Gerber, Hammers, Wissing, Kachhap, Luo, Xing, Björk, Olsson, Björk, Leanderson: Tasquinimod Is an Allosteric Modulator of HDAC4 survival signaling within the compromised cancer microenvironment. in Cancer research 2013 (PubMed)

  2. Human HDAC4 Protein expressed in Baculovirus infected Insect Cells - ABIN2004793 : Cernotta, Clocchiatti, Florean, Brancolini: Ubiquitin-dependent degradation of HDAC4, a new regulator of random cell motility. in Molecular biology of the cell 2011 (PubMed)

More Proteins for Histone Deacetylase 4 (HDAC4) Interaction Partners

Fruit Fly (Drosophila melanogaster) Histone Deacetylase 4 (HDAC4) interaction partners

  1. RNAi-mediated knockdown of HDAC4 in Drosophila dampens circadian function.

  2. HDAC4 is not only a repressor of long-term memory, but also modulates normal memory formation

  3. dHDAC4, is a novel, catalytically active class II Drosophila histone deacetylase (show HDAC1 Proteins) and is involved in the segmentation regulatory pathway and suggested complex transcriptional regulation as a potential mechanism that controls its expression

Human Histone Deacetylase 4 (HDAC4) interaction partners

  1. HDAC4 increases endogenous SIRT1 (show SIRT1 Proteins) expression by enhancing its sumoylation modification levels

  2. we demonstrate that nuclear HDAC4 is a key regulator promoting the progressive epithelial ovarian cancer on fibrillar collagen matrices

  3. HDAC4 destabilizes MAP1S (show MAP1S Proteins), suppresses autophagy flux and promotes the accumulation of mHTT aggregates.

  4. Mechanical compression regulates chondrocyte gene expression through HDAC4 relocation from the cell's cytoplasm to the nucleus via PP2A (show PPP2R4 Proteins)-dependent HDAC4 dephosphorylation.

  5. Elevated HDAC-4 expression in Pancreatic Adenocarcinoma was significantly associated with the absence of organ metastases and borderline with the absence of lymph node metastases and tumor proliferative capacity.

  6. Over-expression of HDAC4 suppressed the transcription of genes involved in energy expenditure in a SIRT1 (show SIRT1 Proteins)-dependent manner. In contrast, HDAC4 knockdown/inhibition neutralized the effect of IFN-gamma (show IFNG Proteins) on cellular metabolism by normalizing SIRT1 (show SIRT1 Proteins) expression

  7. HDAC4-RelB (show RELB Proteins)-p52 (show FKBP4 Proteins) complex maintains repressive chromatin around proapoptotic genes Bim (show BCL2L11 Proteins) and BMF (show BMF Proteins) and regulates multiple myeloma survival and growth

  8. Among the class II HDACs, HDAC4 interacted with both MR and HDAC3 (show HDAC3 Proteins) after aldosterone stimulation. The nuclear translocation of HDAC4 was mediated by protein kinase A (PKA) and protein phosphatases (PP)

  9. Results show that overexpression of miR10b in ER-positive breast cancer cell lines led to increased resistance to tamoxifen and HDAC4 was identified as its direct target. MiR10b-HDAC4 nexus may be one of the molecular mechanism of tamoxifen resistance.

  10. the pro-inflammatory role of miR (show MLXIP Proteins)-22 in emphysema has revealed that HDAC4 specifically regulated smoking-related lung inflammation and TH17 responses

Mouse (Murine) Histone Deacetylase 4 (HDAC4) interaction partners

  1. HDAC4 (show HDAC5 Proteins) increases endogenous SIRT1 (show SIRT1 Proteins) expression by enhancing its sumoylation modification levels

  2. postmitotic expression SOD1G93A mutant gene promotes a FAPS phenotype in C2C12 cells, by upregulating HDAC4 (show HDAC5 Proteins) protein and preventing the BAF60C (show SMARCD3 Proteins)-SWI (show SMARCA1 Proteins)/SNF (show SNRPA Proteins) complex myogenic commitment

  3. miR (show MLXIP Proteins)-29a was involved in the regulation of HDAC4 (show HDAC5 Proteins) and modulation of the profibrogenic phenotype in hepatic stellate cells.

  4. This study demonstrated that hdac4 (show HDAC5 Proteins) increase in skeletal muscle in muscle atrophy.

  5. These results demonstrate that miR (show MLXIP Proteins)-140 ensures the robustness of the PTHrP/HDAC4 (show HDAC5 Proteins) regulatory system by suppressing MEF2C (show MEF2C Proteins)-inducing stimuli.

  6. The data of this study demonstrated pronounced and distinctively different changes in the expression of class IV HDAC (show HDAC3 Proteins) in subfields of the hippocampus after an acute status epilepticus, during epileptogenesis and in chronic TLE.

  7. Phosphorylation and localization of HDAC4 (show HDAC5 Proteins) contributes to establishing fiber type-specific transcriptional programs.

  8. HDAC4 (show HDAC5 Proteins) is a novel inflammatory pain mediator.

  9. Glycolysis-dependent histone deacetylase 4 (show HDAC5 Proteins) degradation regulates inflammatory cytokine production.

  10. HDAC4 (show HDAC5 Proteins) is a novel regulator of Pax7 (show PAX7 Proteins)-dependent satellite cell proliferation.

Zebrafish Histone Deacetylase 4 (HDAC4) interaction partners

  1. Results demonstrate that Hdac4 is a regulator of cranial neural crest-derived palatal skeletal precursors during early embryogenesis.

Cow (Bovine) Histone Deacetylase 4 (HDAC4) interaction partners

  1. our results revealed the mechanism in which miR-1 and miR (show MYLIP Proteins)-206 positively regulate bovine skeletal muscle satellite cell myogenic differentiation via Pax7 (show PAX7 Proteins) and HDAC4 downregulation.

HDAC4 Protein Profile

Protein Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

Gene names and symbols associated with Histone Deacetylase 4 Proteins (HDAC4)

  • histone deacetylase 4 (PTRG_03699)
  • histone deacetylase 4 (PGTG_15512)
  • CG1770 gene product from transcript CG1770-RG (HDAC4)
  • DanaGF18710-PA (DanaHDAC4)
  • histone deacetylase 4 (HDAC4)
  • histone deacetylase 4 (Hdac4)
  • histone deacetylase 4 (hdac4)
  • 4932408F19Rik protein
  • AHO3 protein
  • AI047285 protein
  • BDMR protein
  • CG1770 protein
  • DanaGF18710 protein
  • dana_GLEANR_19966 protein
  • dHDAC4 protein
  • Dmel\\CG1770 protein
  • dmHDA405 protein
  • GC1770 protein
  • GF18710 protein
  • HA6116 protein
  • HD4 protein
  • HDAC protein
  • HDAC-4 protein
  • HDAC-A protein
  • HDAC4 protein
  • HDAC4a protein
  • HDACA protein
  • wu:fa96d08 protein
  • wu:fc56f08 protein
  • zgc:152701 protein

Protein level used designations for Histone Deacetylase 4 Proteins (HDAC4)

histone deacetylase 4 , CG1770-PB , CG1770-PD , CG1770-PE , CG1770-PF , CG1770-PG , CG1770-PH , CG1770-PI , CG1770-PJ , HDAC4-PB , HDAC4-PD , HDAC4-PE , HDAC4-PF , HDAC4-PG , HDAC4-PH , HDAC4-PI , HDAC4-PJ , DanaGF18710-PA , DanaHDAC4-PA , GF18710-PA , HDAC4 , HDAC4-PA , histone deacetylase A , HD4

GENE ID SPECIES
6341931 Pyrenophora tritici-repentis Pt-1C-BFP
10547054 Puccinia graminis f. sp. tritici CRL 75-36-700-3
32278 Drosophila melanogaster
6507946 Drosophila ananassae
9759 Homo sapiens
208727 Mus musculus
363287 Rattus norvegicus
374207 Gallus gallus
568877 Danio rerio
607662 Canis lupus familiaris
517559 Bos taurus
Selected quality suppliers for HDAC4 Proteins (HDAC4)
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