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Histone H4 Transcription Factor Proteins (HINFP)

HINFP encodes a transcription factor that interacts with methyl-CpG-binding protein-2 (MBD2), a component of the MeCP1 histone deacetylase (HDAC) complex, and plays a role in DNA methylation and transcription repression. Additionally we are shipping HINFP Antibodies (42) and HINFP Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HINFP 25988 Q9BQA5
HINFP 102423 Q8K1K9
Rat HINFP HINFP 300665  
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Top HINFP Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

HINFP Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Histone H4 Transcription Factor (HINFP) Interaction Partners

Human Histone H4 Transcription Factor (HINFP) interaction partners

  1. purified and functionally characterized the critical transcription factor HiNF-P, which is required for E2F-independent activation of the histone H4 multigene family

  2. These results suggest that transcriptional repression of Rb by MIZF could be one of the critical determinants in myogenic differentiation.

  3. HiNF-P interacts directly with p220(NPAT) to coactivate histone genes during S phase.

  4. the transcriptional silencing of the 14-3-3sigma gene is caused by promoter CpG island methylation associated with MBD2, which may play an important role in prostate cancer progression during the invasive and metastatic stages of the disease

  5. These results suggest that RFP (show FPR2 Proteins) is a mediator connecting several MBD (show DPEP1 Proteins) proteins and allowing the formation of a more potent transcriptional repressor complex.

  6. HiNF-P is a bifunctional regulator of cell cycle controlled histone H4 gene transcription.

  7. HiNF-P-dependent stabilization of p220NPAT reinforces signaling through the cyclin E (show CCNE1 Proteins)/CDK2 (show CDK2 Proteins)/p220NPAT pathway and contributes to coordinate control of histone gene expression.

  8. HiNF-P/P220NPAT regulates expression of nonhistone targets that influence competency for cell cycle progression.

  9. a novel HiNF-P-specific conserved region represents a DNA-binding determinant that plays a role in mediating histone gene expression during the cell cycle and defines HiNF-P as a cell cycle regulatory member of the zinc finger transcription factor (show OSR1 Proteins) family

  10. Results suggest that cyclin-dependent kinase inhibitors selectively control stimulation of the histone H4 gene promoter by the p220(NPAT)/HiNF-P complex.

Mouse (Murine) Histone H4 Transcription Factor (HINFP) interaction partners

  1. simultaneous loss of both Hinfp and the p53 (show TP53 Proteins) checkpoint is detrimental to normal cell growth and may predispose to cellular transformation.

  2. Data show that conditional ablation of HINFP compromises cell proliferation, impairs DNA synthesis, alters nucleosome spacing and increases double-stranded DNA damage.

  3. The in vivo co-expression of Hinfp and histone H4 genes is consistent with the biological function of Hinfp as a principal transcriptional regulator of histone H4 gene expression during mouse development.

  4. The dependence of HiNF-P gene transcription on cyclin E/CDK2/p220NPAT signaling defines a novel feed-forward loop that may sustain HiNF-P expression in proliferating cells to support the cell cycle regulated synthesis of histone H4 proteins.

  5. Data indicate that the CDK2/cyclin E/p220(NPAT)/HINFP/histone gene signaling pathway at the G1/S phase transition is an essential, nonredundant cell cycle regulatory mechanism that is established early in embryogenesis.

HINFP Protein Profile

Protein Summary

This gene encodes a transcription factor that interacts with methyl-CpG-binding protein-2 (MBD2), a component of the MeCP1 histone deacetylase (HDAC) complex, and plays a role in DNA methylation and transcription repression. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with HINFP

  • histone H4 transcription factor (HINFP)
  • histone H4 transcription factor (hinfp)
  • histone H4 transcription factor (Hinfp)
  • AA589481 protein
  • HiNF-P protein
  • Mizf protein
  • RGD1311492 protein
  • wu:fi67c06 protein
  • zgc:66200 protein
  • ZNF743 protein

Protein level used designations for HINFP

MBD2 (methyl-CpG-binding protein)-interacting zinc finger protein , MBD2-interacting zinc finger 1 , MBD2-interacting zinc finger protein , histone H4 gene-specific protein HiNF-P , histone nuclear factor P , methyl-CpG-binding protein 2-interacting zinc finger protein , MBD2-interacting zinc finger , hiNF-P

GENE ID SPECIES
25988 Homo sapiens
406733 Danio rerio
446475 Xenopus laevis
610612 Canis lupus familiaris
511965 Bos taurus
102423 Mus musculus
300665 Rattus norvegicus
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