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In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Additionally we are shipping HOXA5 Proteins (11) and many more products for this protein.
Showing 10 out of 117 products:
Human Monoclonal HOXA5 Primary Antibody for ELISA, WB - ABIN393399
Ester, Weymouth, Burt, Wise, Scott, Gurnett, Dobbs, Blanton, Hecht: Altered transmission of HOX and apoptotic SNPs identify a potential common pathway for clubfoot. in American journal of medical genetics. Part A 2009
Show all 5 references for 393399
Human Polyclonal HOXA5 Primary Antibody for EIA, WB - ABIN453110
Chen, Gorski: Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5. in Blood 2008
Show all 2 references for 453110
Human Monoclonal HOXA5 Primary Antibody for IF, ELISA - ABIN516607
Schummer, Thorpe, Giraldez, Bergan, Tewari, Urban: Evaluating Serum Markers for Hormone Receptor-Negative Breast Cancer. in PLoS ONE 2015
Human Polyclonal HOXA5 Primary Antibody for ELISA, WB - ABIN334419
Okada, Jiang, Lemieux, Jeannotte, Su, Zhang: Leukaemic transformation by CALM-AF10 involves upregulation of Hoxa5 by hDOT1L. in Nature cell biology 2006
Pig (Porcine) Polyclonal HOXA5 Primary Antibody for ELISA, WB - ABIN4319692
Yoo, Park, Kim, Jung, Chang: Epigenetic inactivation of HOXA5 and MSH2 gene in clear cell renal cell carcinoma. in Pathology international 2010
Cow (Bovine) Polyclonal HOXA5 Primary Antibody for IHC, WB - ABIN2777305
Boucherat, Montaron, Bérubé-Simard, Aubin, Philippidou, Wellik, Dasen, Jeannotte: Partial functional redundancy between Hoxa5 and Hoxb5 paralog genes during lung morphogenesis. in American journal of physiology. Lung cellular and molecular physiology 2013
loss of HOXA5 in mammary cells leads to loss of epithelial traits, an increase in stemness and cell plasticity, and the acquisition of more aggressive phenotypes.
ATRA may inhibit the proliferation of K562 cells and promote apoptosis by upregulating the HOXA5 mRNA and protein expression.
Knockdown of HOXA5 suppressed the proliferation and metastasis of esophageal squamous cell cancer cells.
high expression levels of HOXA5 mRNA and protein in children with ALL indicate that HOXA5 is closely associated with childhood ALL.
Downregulation of HOXA5 by shRNA may trigger apoptosis and overcome drug resistance in leukemia cells.
HOXA5-induced apoptosis was p53 (show TP53 Antibodies)-independent.
Among the mechanosensitive genes, the two transcription factors, HoxA5 and Klf3 (show KLF3 Antibodies), contain cAMP-response-elements methylation of which could serve as a mechanosensitive master switch in gene expression in atherosclerosis. (Review)
In colon cancer, HOXA5 is downregulated, and its re-expression induces loss of the cancer stem cell phenotype, preventing tumor progression and metastasis.
Ectopic expression of HOXA5 in highly invasive cancer cells suppressed cell migration, invasion, and filopodia formation in vitro and inhibited metastatic potential in vivo.
The NK AML (show RUNX1 Antibodies) patients with NPM1 (show NPM1 Antibodies) mutations exhibited elevated HOXA4 (show HOXA4 Antibodies) methylation and expression levels of HOXA5 and MEIS1 (show MEIS1 Antibodies) compared with the NPM1 (show NPM1 Antibodies) wildtype patients.
mapping analysis allowed us to build hypotheses regarding HOXA5 functions in the nervous system after birth, such as a potential role in the establishment and refinement/plasticity of precerebellar circuits during postnatal and adult life
In presence of these inducing agents, lipid accumulation as well as expression of HoxA1 (show HOXA1 Antibodies), HoxA5, HoxC4 (show HOXC4 Antibodies) &HoxC8 (show HOXC8 Antibodies) markedly enhanced. Irrespective of presence or absence of T3, insulin (show INS Antibodies) down regulates HoxA10 (show HOXA10 Antibodies). T3 results in over expression of HoxA5, HoxC4 (show HOXC4 Antibodies) and HoxC8 (show HOXC8 Antibodies) genes, whereas insulin (show INS Antibodies) up regulates expression of only HoxC8 (show HOXC8 Antibodies)
Methylation profiling of HoxA5 gene promoter shows higher methylation in adult as compared to fetus in various somatic tissues of mouse being highest in adult spleen. However q-PCR results show higher expression during fetal stages being highest in fetal intestine followed by brain, liver and spleen. These results clearly indicate a strict correlation between DNA methylation (show HELLS Antibodies) and tissue-specific gene expression.
HoxA5 represents a novel molecule for restricting pathological and tumorigenic angiogenesis.
Enforced expression of Hoxa5 in haematopoietic stem cells leads to aberrant erythropoiesis in vivo.
YY1 (show YY1 Antibodies) acts as a transcriptional activator of Hoxa5 gene expression in mouse organogenesis.
Hoxa5 and Hoxb5 (show HOXB5 Antibodies) paralog genes share some functions during lung morphogenesis; Hoxa5 plays a predominant role.
Two Hox (show MSH2 Antibodies) genes, Hoxa5 and Hoxc5 (show HOXC5 Antibodies), control diverse aspects of phrenic motor column development.
Hoxa5, a stroma-specific gene, plays a significant role in ovarian biology and may be involved in ovarian cancer predisposition
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.
, homeo box A5
, similar to Homeobox protein Hox-A5 (Hox-1.3) (M2)
, hoxa5a protein
, homeobox protein Hox-1.3
, homeobox protein Hox-A5
, homeo box 1C
, homeobox protein HOXA5
, homeobox protein Hox-1C
, homeobox protein M2
, Homeobox protein Hox-A5