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In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Additionally we are shipping HOXA9 Proteins (9) and many more products for this protein.
Showing 10 out of 94 products:
Chicken Polyclonal HOXA9 Primary Antibody for WB - ABIN2778526
Whelan, Ludwig, Bertrand: HoxA9 induces insulin-like growth factor-1 receptor expression in B-lineage acute lymphoblastic leukemia. in Leukemia 2008
Show all 2 references for ABIN2778526
Human Monoclonal HOXA9 Primary Antibody for IF, ELISA - ABIN561318
Storlie, Jackson, Hutchinson, Grose: Delayed biosynthesis of varicella-zoster virus glycoprotein C: upregulation by hexamethylene bisacetamide and retinoic acid treatment of infected cells. in Journal of virology 2006
Human Polyclonal HOXA9 Primary Antibody for EIA, FACS - ABIN952776
Scott: Vertebrate homeobox gene nomenclature. in Cell 1992
With continued advances in understanding HOXA9-mediated transformation, there is a wealth of opportunity for developing novel therapeutics that would be applicable for greater than 50% of AML (show RUNX1 Antibodies) with overexpression of HOXA9
Data establish HOXA9 as a driver of glioma initiation, aggressiveness and resistance to therapy.
Concurrent ISL1 (show ISL1 Antibodies)/HOXA9 methylation in HG-NMIBC reliably predicted tumour recurrence and progression within one year, and was associated with disease-specific mortality
Increased expression of HOXA9 is associated with acute myeloid leukemia (show BCL11A Antibodies).
Pbx3 contributes to Hoxa9 leukemogenesis through stabilization of the Meis1 (show MEIS1 Antibodies) protein.
HOXA9 and MEIS1 (show MEIS1 Antibodies) overexpression are inversely correlated with relapse and overall survival, so the genes could become useful predictive markers of the clinical course of pediatric acute leukemias.
present study suggests that HOXA9 inhibits migration of lung cancer cells and its hypermethylation is an independent prognostic factor for recurrence-free survival in never-smokers with NSCLC
variants in the HOXA7 (show HOXA7 Antibodies) and HOXA9 genes are not common in Chinese women with Mullerian duct abnormalities
these findings indicate that homeobox A9 regulates the expression of VEGF in epidermal stem cells
HOXA9 methylation is frequent in oral cancers and levels are higher in tumors with greater risk of metastasis. Expression of HOXA9 is low in cells with high levels of methylation and reduced expression appears to confer a growth advantage.
IGF-1 (show IGF1 Antibodies) is a direct HOXA9 target important for hematopoietic transformation.
deficiency of tumor suppressor prep1 accelerates the onset of meis1 (show MEIS1 Antibodies)- hoxa9 leukemogenesis
Hoxa9 collaborates with E2A (show TCF3 Antibodies)-PBX1 (show PBX1 Antibodies) in mouse B cell leukemia in association with Flt3 (show FLT3 Antibodies) activation and decrease of B cell gene expression.
results suggest a previously unidentified role for C/EBPalpha (show CEBPA Antibodies) in maintaining the proliferation required for Hoxa9/Meis1 (show MEIS1 Antibodies)-mediated leukemogenesis
This is the first description of a molecular link between HoxA9 and the regulation of Bcl-2 (show BCL2 Antibodies) family members in acute myeloid leukemia (show BCL11A Antibodies).
HOXA9 may, therefore, stimulate ovarian cancer progression by promoting an immunosuppressive microenvironment via paracrine effects on peritoneal macrophages.
there is an extremely early checkpoint in hematopoietic differentiation critical for B and T lymphopoiesis that can only be transversed through the cooperative action of Hoxa9 and Flt3 (show FLT3 Antibodies) signaling.
High Hoxa9 transgene expression in the embryonic hematopoietic compartment was lethal. Mice with lower levels of Hoxa9 developed a precursor-T-cell lymphoblastic leukemia/lymphoma, accompanied by spontaneous Notch1 (show NOTCH1 Antibodies) mutations.
These findings reveal distinct requirements for Hoxa9 or Hoxa9/Flt3 (show FLT3 Antibodies) molecular circuits in regulation of B versus natural killer and dendritic cell development in bone marrow.
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis. Read-through transcription exists between this gene and the upstream homeobox A10 (HOXA10) gene.
, homeobox protein Hox-A9
, XIHbox 6
, homeobox protein Hox-1G
, homeodomain protein HOXA9
, homeo box A9
, homeobox protein Hox-1.7
, Homeobox gene A7
, homeobox protein Hox-1.1
, homeobox protein Hox-A7
, homeobox protein R5
, homeobox protein A9