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Homeobox B8 Proteins (HOXB8)

HOXB8 is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. Additionally we are shipping HOXB8 Antibodies (65) and HOXB8 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HOXB8 24457  
HOXB8 3218 P17481
HOXB8 15416 P09632
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Top HOXB8 Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,093.67
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,150.50
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,154.17
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details

HOXB8 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Human ,
,
Mouse (Murine)

More Proteins for Homeobox B8 (HOXB8) Interaction Partners

Human Homeobox B8 (HOXB8) interaction partners

  1. Results show that FMRP (show FMR1 Proteins) regulates miR196a-mediated repression of HOXB8 via interaction with the AGO2 (show EIF2C2 Proteins) MID domain.

  2. HOXB8 and KLK11 (show KLK11 Proteins) may be classified as valuable biomarkers, as they can predict the effects of FOLFOX4 chemotherapy in primary advanced colorectal cancer patients

  3. HOXB5 (show HOXB5 Proteins) and HOXB8 are frequently expressed in ovarian serous carcinoma, with anatomic site-related differences for cytoplasmic staining. HOXB8 expression is associated with shorter survival in metastatic serous carcinoma.

Mouse (Murine) Homeobox B8 (HOXB8) interaction partners

  1. Production and Functional Characterization of Murine Osteoclasts Differentiated from ER-Hoxb8-Immortalized Myeloid Progenitor Cells

  2. results demonstrate an important role for the intersection of Lmx1b (show LMX1B Proteins) and Hoxb8::cre expression in the development of nociceptive dorsal horn circuits critical for mechanical and thermal pain processing.

  3. Results show a previously unrecognised link between Hoxb8 expression and microRNAs that provides a new insight into the oncogenic functions of Hoxb8.

  4. Mouse Hoxb8 mutants show unexpected behavior manifested by compulsive grooming and hair removal further, transplantation of wild-type bone marrow into Hoxb8 mutant mice rescues their pathological phenotype.

  5. Data sugest that cooperative binding between Hoxb8 hexapeptide motif and cofactors is a critical element in the fine-tuning of Hoxb8 protein target specificity.

  6. RNA fragments diagnostic of miR (show MLXIP Proteins)-196-directed cleavage of HOXB8 were detected in mouse embryos; results point to a miRNA-mediated mechanism for the posttranscriptional restriction of HOX (show MSH2 Proteins) gene expression during vertebrate development

  7. Hoxb8 inhibited the activity of the telokin (show MYLK Proteins), SM22alpha (show TAGLN Proteins), and smooth muscle alpha-actin (show ACTA2 Proteins) promoters

  8. miR (show MLXIP Proteins)-196 acts upstream of Hoxb8 and Sonic hedgehog (Shh (show SHH Proteins)) in vivo in the context of limb development, thereby identifying a previously observed but uncharacterized inhibitory activity that operates specifically in the hindlimb

  9. Results indicate distinct roles for class 2 Polycomb (show CBX2 Proteins) group complexes in transcriptionally repressed and active domains of Hoxb8 gene.

  10. These results suggest that miR (show MLXIP Proteins)-196 participates in myeloid differentiation of HL60 cells via regulation of HOXB8 expression.

HOXB8 Protein Profile

Protein Summary

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.

Gene names and symbols associated with Homeobox B8 Proteins (HOXB8)

  • homeo box B8 (Hoxb8)
  • homeobox B8 (HOXB8)
  • homeobox B8 (Hoxb8)
  • homeobox protein Hox-B8-like (LOC100627661)
  • Hox-2.4 protein
  • HOX2 protein
  • HOX2D protein
  • Hox2r1a protein

Protein level used designations for Homeobox B8 Proteins (HOXB8)

Hox2.4 homeobox homolog , homeobox gene B8 , homeobox protein Hox-B8 , homeobox protein R1a , homeo box 2D , homeo box B8 , homeobox protein Hox-2.4 , homeobox protein Hox-2D , Hoxb-8

GENE ID SPECIES
24457 Rattus norvegicus
3218 Homo sapiens
491059 Canis lupus familiaris
15416 Mus musculus
395737 Gallus gallus
785855 Bos taurus
100627661 Sus scrofa
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