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Homeobox D11 Proteins (HOXD11)

HOXD11 belongs to the homeobox family of genes. Additionally we are shipping Homeobox D11 Antibodies (53) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HOXD11 3237 P31277
HOXD11 15431 P23813
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Top Homeobox D11 Proteins at

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
Yeast Heterodontus francisci His tag   1 mg Log in to see 56 to 66 Days
Yeast Notophthalmus viridescens His tag   1 mg Log in to see 56 to 66 Days
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days

HOXD11 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
Mouse (Murine)


More Proteins for Homeobox D11 (HOXD11) Interaction Partners

Human Homeobox D11 (HOXD11) interaction partners

  1. POU2F1 (show POU2F1 Proteins) activity regulates HOXD10 (show HOXD10 Proteins) and HOXD11 gene expression in head and neck squamous cell carcinoma, promoting a proliferative and invasive phenotype.

  2. data show no significant difference in HOXD11, HOXD12 (show HOXD12 Proteins) & HOXD13 (show HOXD13 Proteins) genotype frequencies between the autism spectrum disorder & healthy controls, but one SNP in promoter region of HOXD11 was observed in only 4 patients with ASD (show ARSD Proteins)

  3. In human embryonic stem cell (hESCs)differentiation, a 1.8kb region between HOXD11 and HOXD12 (show HOXD12 Proteins) (D11.12) that is associated with PcG proteins was discovered, it shows alteration in nuclease (show DCLRE1C Proteins) sensitivity as hESCs differentiate.

  4. The HOXD11 gene is fused to the NUP98 (show NUP98 Proteins) gene in acute myeloid leukemia (show BCL11A Proteins) with t(2;11)(q31;p15 (show CDKN2B Proteins)).

  5. Our findings do not support the hypothesis that mutations in the HOXD11 coding regions are involved in the pathogenesis of human non-syndromal congenital renal parenchymal malformations.

Mouse (Murine) Homeobox D11 (HOXD11) interaction partners

  1. expressed adjacent to the pisiform in late-stage embryonic limbs, supporting a role for Hox (show MSH2 Proteins) genes in growth plate specification

  2. Hoxa11 (show HOXA11 Proteins) and Hoxd11 regulate chondrocyte differentiation upstream of Runx2 (show RUNX2 Proteins) and Shox2 (show SHOX2 Proteins) in mice.

  3. Hox11 (show TLX1 Proteins) genes (Hoxa11 (show HOXA11 Proteins), Hoxc11 (show HOXC11 Proteins) and Hoxd11) co-regulate and coordinate the development of zeugopod skeletal elements and adjacent elbow and knee joints, and dictate joint identity, morphogenesis and anatomical and functional organization.

  4. mice individually mutant for Hoxa11 (show HOXA11 Proteins) or Hoxd11 show no discernible kidney abnormalities. Hoxa11 (show HOXA11 Proteins)/Hoxd11 double mutants, however, demonstrate hypoplasia of the kidneys

  5. analysis of the Hoxd11 duplication demonstrated that the Hoxd11 can perform some functions supplied by its paralogue Hoxa11 (show HOXA11 Proteins), the defects in forelimb bones are corrected when extra copies of Hoxd11 are present in the Hoxa11 (show HOXA11 Proteins) homozygous mutant background

  6. malformation of the forelimb zeugopod in Hoxa11 (show HOXA11 Proteins)/Hoxd11 double mutants is a consequence of interruption at multiple steps during the formation of the radius and ulna

  7. early posterior restriction of Hox (show MSH2 Proteins) gene products sets up an anterior-posterior prepattern, which determines the localized activation of Shh (show SHH Proteins); this signal is then translated into digit morphological asymmetry by promoting the late expression of Hoxd genes

  8. identify the multiple molecular pathways downstream of Hoxa11 (show HOXA11 Proteins)/Hoxd11 function in the developing kidney

  9. Mice lacking all Hox11 (show TLX1 Proteins) activity fail to form metanephric kidney structures; when Hoxd11 is ectopically activated in the anterior mesonephros, we observe a partial transformation to a metanephric program of development.

  10. mice mutant for Hoxd11 and Hoxa11 (show HOXA11 Proteins) show absence of radius and ulna, anterior homeotic transformation of vertebra, and severe kidney defects, suggesting Hoxd11 and Hoxa11 (show HOXA11 Proteins) act together to specify limb outgrowth and patterning of proximodistal axis

Homeobox D11 (HOXD11) Protein Profile

Protein Summary

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The product of the mouse Hoxd11 gene plays a role in forelimb morphogenesis.

Gene names and symbols associated with Homeobox D11 Proteins (HOXD11)

  • homeo box D11a (hoxd11a)
  • homeobox D11 (HOXD11)
  • homeobox D11 (hoxd11)
  • homeobox D11 (LOC100229370)
  • homeobox D11 (Hoxd11)
  • E230017H14Rik protein
  • fk50b10 protein
  • GHOX4.6 protein
  • Hox-4.6 protein
  • Hox-5.4 protein
  • Hox-5.5 protein
  • HOX4 protein
  • HOX4F protein
  • hoxc11 protein
  • hoxd-11 protein
  • HOXD11 protein
  • MGC131014 protein
  • wu:fk50b10 protein

Protein level used designations for Homeobox D11 Proteins (HOXD11)

homeobox gene D-11 , homeobox protein Hox-C11 , homeobox protein Hox-D11a , hox-C11 , hox-D11 , homeobox D11 , homeobox protein Hox-D11 , Hox-4.6, mouse, homolog of , homeo box 4F , homeo box D11 , homeobox protein Hox-4F , homeobox protein Hox-4.6 , homeobox protein Hox-5.5 , Hox D11 , chox-4.6 , chox-4E , ghox-4.6 , homeobox protein Hox-4E , homeodomain-containing protein

30405 Danio rerio
459761 Pan troglodytes
488414 Canis lupus familiaris
735036 Xenopus laevis
100229370 Taeniopygia guttata
100358609 Oryctolagus cuniculus
3237 Homo sapiens
609973 Canis lupus familiaris
613983 Bos taurus
15431 Mus musculus
395328 Gallus gallus
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