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HOXD4 belongs to the homeobox family of genes. Additionally we are shipping HOXD4 Antibodies (37) and HOXD4 Proteins (12) and many more products for this protein.
identified heterozygous HOXD4 loss-of-function mutations in three subjects with spinal extradural arachnoid cyst (SEDAC)
The results suggest that genetic polymorphisms in HOXD4 may not be a major contributor to the observed variability in peak BMD (show BEST1 ELISA Kits) in the lumbar spine and the hip in Chinese men and women
microRNA-10a (miR (show MLXIP ELISA Kits)-10a) targets a homologous DNA region in the promoter region of the hoxd4 gene and represses its expression at the transcriptional level
The expression profiles of Hoxd4 and miR (show MLXIP ELISA Kits)-10b transcripts during neural differentiation of mouse embryonal carcinoma (EC) P19 (show CDKN2D ELISA Kits) cells are co-ordinately regulated and generated by Drosha (show DROSHA ELISA Kits) cleavage.
Data provide the basis for future studies in pathogenesis of cartilage defects in Hoxc8 (show HOXC8 ELISA Kits)- and Hoxd4-transgenic mice.
Af9 (show MLLT3 ELISA Kits) null mutation affects Hoxd-4 gene expression
The sequence of regulatory elements, including a DR5 (show TNFRSF10B ELISA Kits) type retinoic acid response element (RARE) required for Hoxd4 neural enhancer activity, are highly conserved, zebrafish and mouse neural enhancers function identically in transgenic mouse embryos.
detected chromatin changes at the Hoxd4 locus during neurogenesis in P19 cells and embryonic day 8.0 (E8.0) and E10.5 embryos
a new molecular link, completing a feedback circuit between retinoic acid receptor beta (show RARB ELISA Kits), Hoxb4 (show HOXB4 ELISA Kits) and Hoxd4
Results identify components of the Hoxd4 P1 promoter directing expression in neurally differentiating retinoic acid-treated P19 cells.
results reveal an evolutionarily conserved role for Pax6 (show PAX6 ELISA Kits) in AP-restricted expression of vertebrate Hoxd4 orthologs
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in determining positional values in developing limb buds. Alternatively spliced variants have been described but their full length nature has not been determined.
, Hox-4.2, mouse, homolog of homeo box X
, homeobox protein HHO.C13
, homeobox protein Hox-4B
, homeobox protein Hox-5.1
, homeobox protein Hox-D4
, homeo box D4
, homeobox protein Hox-4.2
, homeobox protein Hox-A
, Homeobox protein Hox-D4