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Hook Homolog 1 (Drosophila) Proteins (HOOK1)

HOOK1 encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. Additionally we are shipping Hook Homolog 1 (Drosophila) Antibodies (60) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HOOK1 77963 Q8BIL5
Rat HOOK1 HOOK1 313370  
HOOK1 51361 Q9UJC3
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Top Hook Homolog 1 (Drosophila) Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

HOOK1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for Hook Homolog 1 (Drosophila) (HOOK1) Interaction Partners

Mouse (Murine) Hook Homolog 1 (Drosophila) (HOOK1) interaction partners

  1. azh mutation is due to a deletion of exons 10 and 11 in the murine Hook1 gene leading to a non-functional protein. Our results indicate that loss of Hook1 function results in ectopic positioning of microtubular structures within the spermatid

  2. Hook1 and Ankyrin G are co-locolized, Hook1 also localizes to additional regions of the cell devoid of Ankyrin G where it interacts with other proteins.

  3. Multiple samples of ejaculated spermatozoa from normal fertile C57BL/6 and infertile Hook1/Hook1 (formerly known as azh/azh) mutant males from uteri after mating.

Human Hook Homolog 1 (Drosophila) (HOOK1) interaction partners

  1. SHP2 (show PTPN11 Proteins) positively regulates TGFbeta1 (show TGFB1 Proteins)-induced epithelial-mesenchymal transition modulated by its novel interacting protein Hook1.

  2. Hook1, a microtubule- and cargo-tethering protein, recognized the cytoplasmic tail of CD147 (show BSG Proteins) to help sort it and CD98 (show SLC3A2 Proteins) into Rab22a (show RAB22A Proteins)-dependent tubules associated with recycling.

  3. novel interactions between the microtubule-binding Hook1 and the large family of Rab (show HRB Proteins) GTPases also suggest a link between CLN3 (show CLN3 Proteins) function, microtubule cytoskeleton and endocytic membrane trafficking

  4. These data suggest that the FTS/Hook/FHIP complex functions to promote vesicle trafficking and/or fusion via the homotypic vacuolar protein sorting complex.

Hook Homolog 1 (Drosophila) (HOOK1) Protein Profile

Protein Summary

This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined.

Gene names and symbols associated with HOOK1

  • hook homolog 1 (Drosophila) (HOOK1)
  • hook homolog 1 (hook1)
  • hook homolog 1 (Drosophila) (Hook1)
  • hook microtubule-tethering protein 1 (HOOK1)
  • protein Hook homolog 1-like (LOC785042)
  • A930033L17Rik protein
  • azh protein
  • HK1 protein
  • HOOK1 protein
  • si:dkey-183n20.14 protein

Protein level used designations for HOOK1

hook homolog 1 (Drosophila) , protein Hook homolog 1 , abnormal spermatozoon head shape , mHK1 , h-hook1 , hHK1 , hook homolog 1

GENE ID SPECIES
456895 Pan troglodytes
570393 Danio rerio
77963 Mus musculus
424675 Gallus gallus
479553 Canis lupus familiaris
100525467 Sus scrofa
313370 Rattus norvegicus
51361 Homo sapiens
785042 Bos taurus
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