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Host Cell Factor C2 Proteins (HCFC2)

The product encoded by HCFC2 is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. Additionally we are shipping Host Cell Factor C2 Antibodies (42) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HCFC2 29915 Q9Y5Z7
HCFC2 67933  
Rat HCFC2 HCFC2 314704 Q5RKG2
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Top Host Cell Factor C2 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Escherichia coli (E. coli) Mouse His tag   10 μg Log in to see 5 Days
$154.00
Details

HCFC2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Host Cell Factor C2 (HCFC2) Interaction Partners

Human Host Cell Factor C2 (HCFC2) interaction partners

  1. Molecular modelling of HCII (show SERPIND1 Proteins) 1-75 predicted those portions of the acidic extension that had been previously visualized in crystal structures, and suggested that an alpha-helix found between residues 26 and 36 stabilizes one found between residues 61-67.

  2. In this study, we demonstrate a previously unknown role for HCII (show SERPIND1 Proteins) in host defense.

  3. HCII (show SERPIND1 Proteins) potentiates the activation of vascular endothelial cells and the promotion of angiogenesis in response to hindlimb ischemia via an AMPK (show PRKAA1 Proteins)-eNOS (show NOS3 Proteins) signaling pathway.

  4. Plasma heparin cofactor II (show SERPIND1 Proteins) activity was independently and inversely associated with the development of cardiac remodeling, including cardiac concentric change, left atrial enlargement and left ventricular diastolic dysfunction.

  5. [REVIEW]HCII (show SERPIND1 Proteins) protects against vascular remodeling, including atherosclerosis

  6. potential for oversulfated disaccharides in controlling HCII (show SERPIND1 Proteins)-regulated thrombin (show F2 Proteins) generation

  7. Aspartic acid residues 72 and 75 and tyrosine-sulfate 73 of heparin cofactor II (show SERPIND1 Proteins) promote

  8. role of basic amino acids of the A helix of heparin cofactor II (show SERPIND1 Proteins) in heparin- or dermatan sulfate-mediated thrombin (show F2 Proteins) inhibition.

  9. Altering heparin cofactor II (show SERPIND1 Proteins) at VAL439 (P6) either impairs inhibition of thrombin (show F2 Proteins) or confers elastase resistance.

  10. The interactions of HCII (show SERPIND1 Proteins) with various heparins in solution competition experiments using SPR (show SPR Proteins) show that while calcium enhances this interaction, the activity of heparin-HCII (show SERPIND1 Proteins) complex against thrombin (show F2 Proteins) is not calcium dependent but can be enhanced by it.

Host Cell Factor C2 (HCFC2) Protein Profile

Protein Summary

The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in this gene are associated with heparin cofactor II deficiency.

Gene names and symbols associated with Host Cell Factor C2 Proteins (HCFC2)

  • host cell factor C2 (HCFC2)
  • host cell factor C2 (Hcfc2)
  • serpin peptidase inhibitor, clade D (heparin cofactor), member 1 (SERPIND1)
  • 1700129L13Rik protein
  • AU019838 protein
  • D22S673 protein
  • HC2 protein
  • HCF-2 protein
  • HCF2 protein
  • HCII protein
  • HLS2 protein
  • LS2 protein
  • THPH10 protein

Protein level used designations for Host Cell Factor C2 Proteins (HCFC2)

C2 factor , host cell factor 2 , HCF-2 , heparin cofactor 2 , leuserpin 2 , protease inhibitor leuserpin-2 , serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1 , serpin D1

GENE ID SPECIES
29915 Homo sapiens
475449 Canis lupus familiaris
505341 Bos taurus
67933 Mus musculus
314704 Rattus norvegicus
3053 Homo sapiens
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