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Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Additionally we are shipping HIP1R Proteins (5) and many more products for this protein.
Showing 10 out of 71 products:
Dog (Canine) Monoclonal HIP1R Primary Antibody for IF, WB - ABIN968746
Engqvist-Goldstein, Kessels, Chopra, Hayden, Drubin: An actin-binding protein of the Sla2/Huntingtin interacting protein 1 family is a novel component of clathrin-coated pits and vesicles. in The Journal of cell biology 2000
Show all 3 references for ABIN968746
Human Polyclonal HIP1R Primary Antibody for EIA, FACS - ABIN952739
Wilbur, Chen, Manalo, Hwang, Fletterick, Brodsky: Actin binding by Hip1 (huntingtin-interacting protein 1) and Hip1R (Hip1-related protein) is regulated by clathrin light chain. in The Journal of biological chemistry 2008
Show all 2 references for ABIN952739
our findings support the conclusion that the rs12817488 in CCDC62/HIP1R polymorphism may increase the risk of Parkinson's disease in the Chinese Han population.
We conclude that HIP1R expression is strongly indicative of survival in diffuse large B-cell lymphoma
STK39 (show STK39 Antibodies) (rs2102808) and CCDC62 (show CCDC62 Antibodies)/HIP1R (rs12817488) do not appear to influence PD risk.
HIP1r plays an important role in regulating the attachment of spindle microtubules to chromosomes during mitosis, an event that is required for accurate congression and segregation of chromosomes.
HIP1 (show HIP1 Antibodies) and HIP12 display differential binding to F-actin, AP2 (show GTF3A Antibodies), and clathrin. Identification of a novel interaction with clathrin light chain. (HIP12)
both HIP1r and HIP1 (show HIP1 Antibodies) bind inositol lipids via their epsin N-terminal homology (ENTH (show CLINT1 Antibodies)) domains
Hip1R has a role in making the interaction between actin and the endocytic machinery functional and transient
The F-actin binding capacity of Hip12 is regulated by intrasteric occlusion of primary actin-binding determinants within the Hip12 I/LWEQ module.
the stability of intergenerational transmission of a variable number tandem repeat (VNTR) polymorphism, found in the Huntingtin interacting protein-1 related gene (HIP12/HIP1R) that is mapped to the chromosome 12q24.31 region.
characterize the F-actin-binding region of HIP1R, termed the talin-HIP1/R/Sla2p actin-tethering C-terminal homology (THATCH) domain
Specific expression of mHip1r in the embryonic brain and secretory glands suggests a possible role for Hip1r in normal development and in the pathology of HD.
IFNgamma was required for the mucous cell hypertrophy and hyperplasia observed in Hip1r-deficient mice. IFNgamma is critical for the development of the gastric epithelial cell metaplasia that results from parietal cell atrophy in the Hip1r-deficient mice.
This study characterized gastric gland development in wild-type and Hip1r-deficient mice to define normal development, as well as the timing and sequence of the cellular transformation events in the mutant stomach.
mice deficient in both HIP1 (show HIP1 Antibodies) and HIP1r have accelerated development of abnormalities seen in Hip1 (show HIP1 Antibodies) -deficient mice, including kypholordosis and growth defects
roles of Hip1 and Hip1R in affecting clathrin assembly and actin distribution are mediated by their interaction with the conserved sequence of clathrin light chains.
Degenerative phenotypes seen in knockout mice are due mainly to HIP1 (show HIP1 Antibodies) and HIP1r protein deficiency rather than altered expression of neighboring genes or disrupted intronic elements.
Hip1r plays a significant role in gastric physiology, mucosal architecture, and secretory membrane dynamics in parietal cells.
Actin binding by Hip1 (huntingtin-interacting protein 1 (show HIP1 Antibodies)) and Hip1R (Hip1-related protein) is regulated by clathrin light chain
Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3- phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.
huntingtin interacting protein 1 related
, huntingtin interacting protein-1-related
, coiled-coil domain-containing protein 60
, huntingtin-interacting protein 1-related protein
, huntingtin interacting protein 1-related
, huntingtin-interacting protein 1-related protein-like
, HIP1-related protein
, huntingtin interacting protein 12
, huntingtin-interacting protein 12