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Huntingtin Interacting Protein 1 Related Proteins (HIP1R)

Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Additionally we are shipping HIP1R Antibodies (71) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat HIP1R HIP1R 81917  
HIP1R 9026 O75146
HIP1R 29816 Q9JKY5
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Top HIP1R Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

HIP1R Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Huntingtin Interacting Protein 1 Related (HIP1R) Interaction Partners

Human Huntingtin Interacting Protein 1 Related (HIP1R) interaction partners

  1. our findings support the conclusion that the rs12817488 in CCDC62/HIP1R polymorphism may increase the risk of Parkinson's disease in the Chinese Han population.

  2. We conclude that HIP1R expression is strongly indicative of survival in diffuse large B-cell lymphoma

  3. STK39 (show STK39 Proteins) (rs2102808) and CCDC62 (show CCDC62 Proteins)/HIP1R (rs12817488) do not appear to influence PD risk.

  4. HIP1r plays an important role in regulating the attachment of spindle microtubules to chromosomes during mitosis, an event that is required for accurate congression and segregation of chromosomes.

  5. HIP1 (show HIP1 Proteins) and HIP12 display differential binding to F-actin, AP2 (show GTF3A Proteins), and clathrin. Identification of a novel interaction with clathrin light chain. (HIP12)

  6. both HIP1r and HIP1 (show HIP1 Proteins) bind inositol lipids via their epsin N-terminal homology (ENTH (show CLINT1 Proteins)) domains

  7. Hip1R has a role in making the interaction between actin and the endocytic machinery functional and transient

  8. The F-actin binding capacity of Hip12 is regulated by intrasteric occlusion of primary actin-binding determinants within the Hip12 I/LWEQ module.

  9. the stability of intergenerational transmission of a variable number tandem repeat (VNTR) polymorphism, found in the Huntingtin interacting protein-1 related gene (HIP12/HIP1R) that is mapped to the chromosome 12q24.31 region.

  10. characterize the F-actin-binding region of HIP1R, termed the talin-HIP1/R/Sla2p actin-tethering C-terminal homology (THATCH) domain

Mouse (Murine) Huntingtin Interacting Protein 1 Related (HIP1R) interaction partners

  1. Specific expression of mHip1r in the embryonic brain and secretory glands suggests a possible role for Hip1r in normal development and in the pathology of HD.

  2. IFNgamma was required for the mucous cell hypertrophy and hyperplasia observed in Hip1r-deficient mice. IFNgamma is critical for the development of the gastric epithelial cell metaplasia that results from parietal cell atrophy in the Hip1r-deficient mice.

  3. This study characterized gastric gland development in wild-type and Hip1r-deficient mice to define normal development, as well as the timing and sequence of the cellular transformation events in the mutant stomach.

  4. mice deficient in both HIP1 (show HIP1 Proteins) and HIP1r have accelerated development of abnormalities seen in Hip1 (show HIP1 Proteins) -deficient mice, including kypholordosis and growth defects

  5. roles of Hip1 and Hip1R in affecting clathrin assembly and actin distribution are mediated by their interaction with the conserved sequence of clathrin light chains.

  6. Degenerative phenotypes seen in knockout mice are due mainly to HIP1 (show HIP1 Proteins) and HIP1r protein deficiency rather than altered expression of neighboring genes or disrupted intronic elements.

  7. Hip1r plays a significant role in gastric physiology, mucosal architecture, and secretory membrane dynamics in parietal cells.

  8. Actin binding by Hip1 (huntingtin-interacting protein 1 (show HIP1 Proteins)) and Hip1R (Hip1-related protein) is regulated by clathrin light chain

HIP1R Protein Profile

Protein Summary

Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3- phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.

Gene names and symbols associated with HIP1R

  • huntingtin interacting protein 1 related (Hip1r)
  • huntingtin interacting protein 1 related (RCJMB04_14f2)
  • huntingtin interacting protein 1 related (hip1r)
  • huntingtin interacting protein 1 related (HIP1R)
  • zgc:158784 (zgc:158784)
  • AA410023 protein
  • DKFZp469N2015 protein
  • hip1r protein
  • HIP3 protein
  • HIP12 protein
  • ILWEQ protein
  • mKIAA0655 protein
  • zgc:92067 protein

Protein level used designations for HIP1R

huntingtin interacting protein 1 related , huntingtin interacting protein-1-related , coiled-coil domain-containing protein 60 , huntingtin-interacting protein 1-related protein , huntingtin interacting protein 1-related , huntingtin-interacting protein 1-related protein-like , HIP-12 , HIP1-related protein , huntingtin interacting protein 12 , huntingtin-interacting protein 12

GENE ID SPECIES
81917 Rattus norvegicus
416836 Gallus gallus
436650 Danio rerio
486251 Canis lupus familiaris
508291 Bos taurus
562138 Danio rerio
100008906 Oryctolagus cuniculus
100144673 Xenopus (Silurana) tropicalis
100172029 Pongo abelii
100481306 Ailuropoda melanoleuca
100154116 Sus scrofa
9026 Homo sapiens
29816 Mus musculus
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