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Hyaluronan Binding Protein 2 Proteins (HABP2)

The protein encoded by HABP2 is an extracellular serine protease that binds hyaluronic acid and is involved in cell adhesion. Additionally we are shipping HABP2 Antibodies (40) and HABP2 Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HABP2 3026 Q14520
HABP2 292126 Q6L711
HABP2 226243 Q8K0D2
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Top HABP2 Proteins at antibodies-online.com

Showing 7 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,759.17
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,759.17
Details
HOST_Human Human His tag   10 μg Log in to see 5 Days
$203.50
Details

HABP2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Rat (Rattus)

Mouse (Murine)

More Proteins for Hyaluronan Binding Protein 2 (HABP2) Interaction Partners

Human Hyaluronan Binding Protein 2 (HABP2) interaction partners

  1. No evidence supporting a role for the HABP2 G534E variant (SNP rs7080536) in papillary thyroid carcinoma.

  2. HABP2 G534E appears to be a susceptibility gene in a subgroup of Familial Non-Medullary Thyroid Cancer (FNMTC), providing important diagnostic implications for this hereditary thyroid cancer.

  3. HABP2, which encodes an extracellular serine protease involved in coagulation, fibrinolysis, and inflammatory pathways, may be a genetic susceptibility locus for early-onset stroke. [Meta-Analysis]

  4. Patients with Gram-negative sepsis caused by B. pseudomallei have abundant FSAP activation, which significantly correlates with stage of disease.

  5. results suggest that the HABP2 G534E variant is a susceptibility gene for familial nonmedullary thyroid cancer

  6. CD44 (show CD44 Proteins) expression in squamous cell carcinoma of the penis cannot predict the need of performing inguinal lymphadenectomy.

  7. FSAP functions in initiation and progression of hepatic fibrosis

  8. The possible effects of omega-3 FA on clinical AF potential could be linked with modulation of circulating FSAP levels.

  9. FSAP activates the NF-kappaB (show NFKB1 Proteins) pathway and the associated downstream pro-inflammatory factors in monocytic cells

  10. The study demonstrated that a single nucleotide polymorphism (Marburg I) in the FSAP gene (HABP-2)results in a weak proteolytic activity against all substrates including FVII (show F7 Proteins).

Mouse (Murine) Hyaluronan Binding Protein 2 (HABP2) interaction partners

  1. Lack of endogenous FSAP impaired the formation of stable, occlusive thrombi in mice.

  2. Results show that the lack of FSAP in mice worsens the outcome of stroke; in the absence of FSAP there was a stronger inflammatory response and lower cell survival due to insufficient activation of the PI3K/AKT (show AKT1 Proteins) pathway

  3. Lower FSAP expression is associated with enhanced liver fibrosis and inflammation in patients with chronic hepatic disorders and murine experimental liver injury.

  4. Data indicate that FSAP mediates proteolytic cleavage and activation of bone morphogenetic protein-2 (BMP-2 (show BMP2 Proteins)).

  5. Hyaluronic acid binding protein 2 (HABP2) negatively regulates vascular integrity via activation of protease-activated receptor/RhoA (show RHOA Proteins)/Rho kinase (show ROCK2 Proteins) signaling. It represents a potential therapeutic target for syndromes of increased vascular permeability.

HABP2 Protein Profile

Protein Summary

The protein encoded by this gene is an extracellular serine protease that binds hyaluronic acid and is involved in cell adhesion. The encoded protein is synthesized as a single chain, but then undergoes an autoproteolytic event to form the functional heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This protease is known to cleave urinary plasminogen activator, coagulation factor VII, and the alpha and beta chains of fibrinogen, but not prothrombin, plasminogen, or the gamma chain of fibrinogen. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with HABP2

  • hyaluronan binding protein 2 (HABP2)
  • hyaluronan binding protein 2 (habp2)
  • hyaluronan binding protein 2 (LOC100223786)
  • hyaluronan binding protein 2 (Habp2)
  • hyaluronic acid binding protein 2 (Habp2)
  • AI035669 protein
  • Fsap protein
  • Habp protein
  • habp2 protein
  • HGFAL protein
  • Phbp protein

Protein level used designations for HABP2

hyaluronan binding protein 2 , hyaluronan-binding protein 2-like , factor VII activating protein , factor VII-activating protease , factor seven-activating protease , hepatocyte growth factor activator-like protein , hyaluronan-binding protein 2 , hyaluronic acid binding protein 2 , plasma hyaluronan binding protein , plasma hyaluronan-binding protein , hyaduronic acid-binding protein 2

GENE ID SPECIES
423898 Gallus gallus
450744 Pan troglodytes
477822 Canis lupus familiaris
548376 Xenopus (Silurana) tropicalis
697495 Macaca mulatta
100068293 Equus caballus
100223786 Taeniopygia guttata
100407842 Callithrix jacchus
100461891 Pongo abelii
100472238 Ailuropoda melanoleuca
100591352 Nomascus leucogenys
3026 Homo sapiens
507993 Bos taurus
292126 Rattus norvegicus
226243 Mus musculus
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