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anti-Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) Antibodies

Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.. Additionally we are shipping HAPLN1 Proteins (10) and HAPLN1 Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HAPLN1 1404 P10915
HAPLN1 12950 Q9QUP5
HAPLN1 29331  
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Top anti-HAPLN1 Antibodies at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-HAPLN1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: NCI-H226 cell lysate WB Suggested Anti-HAPLN1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: NCI-H226 cell lysate  HAPLN1 is strongly supported by BioGPS gene expression data to be expressed in Human NCI-H226 cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB HAPLN1 Antibody (N-term) (ABIN653748) western blot analysis in MCF-7,Jurkat,HepG2 cell line lysates (35 µg/lane).This demonstrates the HAPLN1 antibody detected the HAPLN1 protein (arrow). HAPLN1 Antibody (N-term) (ABIN653748) IHC analysis in formalin fixed and paraffin embedded prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the HAPLN1 Antibody (N-term)for immunohistochemistry. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Flow Cytometric analysis of MCF-7 cells using HAPLN1 Antibody (N-term) Cat.-No AP51999PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in formalin fixed and paraffin embedded prostate carcinoma reacted with HAPLN1 Antibody (N-term) followed which was peroxidase conjugated to the secondary antibody and followed by DAB staining. 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB HAPLN1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$510.36
Details
Human Rabbit APC FACS, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB   50 μL Log in to see 8 to 10 Days
$390.50
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB   200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated WB Western Blot analysis of HAPLN1 expression in transfected 293T cell line by HAPLN1 MaxPab polyclonal antibody.Lane 1: HAPLN1 transfected lysate(40.20 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$418.57
Details

HAPLN1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-HAPLN1 Antibodies

  1. Human Polyclonal HAPLN1 Primary Antibody for FACS, IHC (p) - ABIN653748 : Wheeler, Metter, Tanaka, Absher, Higgins, Zahn, Wilhelmy, Davis, Singleton, Myers, Ferrucci, Kim: Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging. in PLoS genetics 2009 (PubMed)
    Show all 3 references for ABIN653748

  2. Human Polyclonal HAPLN1 Primary Antibody for FACS, IHC (p) - ABIN954321 : Cénit, Blanco-Kelly, de las Heras, Bartolomé, de la Concha, Urcelay, Arroyo, Martínez: Glypican 5 is an interferon-beta response gene: a replication study. in Multiple sclerosis (Houndmills, Basingstoke, England) 2009 (PubMed)
    Show all 2 references for ABIN954321

  3. Human Polyclonal HAPLN1 Primary Antibody for WB - ABIN2777097 : Seyfried, McVey, Almond, Mahoney, Dudhia, Day et al.: Expression and purification of functionally active hyaluronan-binding domains from human cartilage link protein, aggrecan and versican: formation of ternary complexes with defined hyaluronan ... in The Journal of biological chemistry 2005 (PubMed)

More Antibodies against HAPLN1 Interaction Partners

Zebrafish Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) interaction partners

  1. Hapln1a-ECM (show MMRN1 Antibodies) stabilizes the secreted growth factor (show WNT2 Antibodies) Semaphorin3d (Sema3d (show SEMA3D Antibodies)), which has been independently shown to mediate Cx43 (show GJA1 Antibodies) dependent phenotypes during regeneration.

  2. Hapln1a has a critical role in connexin43 (show GJA1 Antibodies)-dependent growth and patterning in the regenerating fin skeleton

  3. The cloning and characterization of crtl1 and its expression during embryogenesis are reported.

Cow (Bovine) Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) interaction partners

  1. stimulates proteoglycan (show Vcan Antibodies) and types II and IX collagens in intervertebral disc cells - stimulates synthesis of matrix molecules

Human Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) interaction partners

  1. CSGalNAcT-1 (show CSGALNACT1 Antibodies) and Hapln-1 may play important roles in the pathogenesis of Kashin-Beck disease and osteoarthritis.

  2. HAPLN1 is overexpressed in metastatic melanoma and is secreted exclusively by the tumor cells

  3. Single-nucleotide polymorphism in the hyaluronan and proteoglycan link protein 1 (HAPLN1) gene is associated with spinal osteophyte formation and disc degeneration in Japanese women.

  4. An in vitro model of perineuronal nets has been developed demonstrating that cartilage link protein (along with hyaluronan synthase) are necessary for their formation.

  5. link protein may function as a stabilizer of the interaction between aggrecan (show ACAN Antibodies) and hyaluronan in cartilage and between versican (show Vcan Antibodies) and hyaluronan in many tissues

  6. SOX9 (show SOX9 Antibodies) is a key regulator of CRTL1

  7. cLP (show CALML3 Antibodies) and versican (show Vcan Antibodies) did not bind directly to each other in solution yet formed ternary complexes with hyaluronan

  8. Overexpression of HAPLN1 and its SP-IgV domain increases tumorigenic properties of mesothelioma. Thus, targeting the SP-IgV domain may be one of the therapeutic approaches in cancer treatment.

Mouse (Murine) Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) interaction partners

  1. Aggrecan (show ACAN Antibodies), link protein and TN-R (show TNR Antibodies) were identified to be essential for the neuroprotective properties of the perineuronal net.

  2. Mef2c (show MEF2C Antibodies) regulates transcription of the extracellular matrix protein cartilage link protein 1 in the developing murine heart.

  3. our findings demonstrate that the formation of perineuronal nets triggered by neuronal Crtl1 synthesis is a key event in the diminuation of plasticity in the adult CNS

  4. there is a general and systemic function of link protein in the organization of extracellular matrix in a number of tissues, possibly interacting with other proteoglycans, such as versican (show Vcan Antibodies), brevican (show BCAN Antibodies), and neurocan (show NCAN Antibodies)

  5. Data suggest that the reported temporal co-expression of cartilage link protein and neurocan (show NCAN Antibodies) in developing brain implicates the possibility of a cooperative function of these molecules.

  6. reduced versican (show Vcan Antibodies) expression may contribute to a subset of the cardiac abnormalities observed in the Crtl1(-/-) mouse.

HAPLN1 Antigen Profile

Protein Summary

Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.

Gene names and symbols associated with HAPLN1

  • hyaluronan and proteoglycan link protein 1 (HAPLN1) antibody
  • hyaluronan and proteoglycan link protein 1a (hapln1a) antibody
  • hyaluronan and proteoglycan link protein 1 (Hapln1) antibody
  • BB099155 antibody
  • CLP antibody
  • Crtl1 antibody
  • Crtl1l antibody
  • CTRL1 antibody
  • hapln1 antibody
  • LP antibody
  • LP-1 antibody
  • wu:fc26f11 antibody
  • wu:fc37g04 antibody
  • wu:fc50e12 antibody
  • wu:fc55h01 antibody

Protein level used designations for HAPLN1

hyaluronan and proteoglycan link protein 1 , cartilage linking protein 1 , fc26f11 , fc37g04 , fc50e12 , fc55h01 , hyaluronan proteoglycan link protein 1 , cartilage link protein , cartilage-link protein , cartilage-linking protein 1 , proteoglycan link protein , Cartilage link protein , cartilage link protein 1 , link protein , LP , link protein precursor (AA -15 to 339)

GENE ID SPECIES
461765 Pan troglodytes
488921 Canis lupus familiaris
493635 Danio rerio
712501 Macaca mulatta
100442758 Pongo abelii
100605865 Nomascus leucogenys
281717 Bos taurus
1404 Homo sapiens
12950 Mus musculus
29331 Rattus norvegicus
396475 Gallus gallus
100034208 Equus caballus
445513 Sus scrofa
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