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anti-Hydrogen Voltage-Gated Channel 1 (HVCN1) Antibodies

HVCN1 encodes a voltage-gated protein channel protein expressed more highly in certain cells of the immune system. Additionally we are shipping HVCN1 Kits (6) and HVCN1 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HVCN1 84329 Q96D96
HVCN1 74096 Q3U2S8
HVCN1 304485  
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Top anti-HVCN1 Antibodies at antibodies-online.com

Showing 10 out of 37 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of HVCN1 Antibody (N-term)(ABIN651233) in Jurkat cell line lysates (35 µg/lane).HVCN1 (arrow) was detected using the purified polyclonal antibody. HVCN1 Antibody (N-term) (ABIN651233) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-RGD1310788 AntibodyTitration: 1.0 µg/mL  Positive Control: Rat Muscle 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Rat Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB 50 μg Log in to see 11 to 13 Days
$541.80
Details
Human Rabbit Biotin FACS, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ICC, IHC, ELISA, WB 100 μL Log in to see 5 to 6 Days
$320.60
Details
Human Rabbit Un-conjugated EIA, IHC (fro), IF, WB Immunohistochemical of paraffin-embedded tonsil sections stained with HVCN1 Antivody Cat.-No AP55392SU-N 0.2 mL Log in to see 6 to 8 Days
$533.50
Details
Human Rabbit PE FACS, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

HVCN1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,


, , , , ,
Mouse (Murine)


Rat (Rattus)


More Antibodies against HVCN1 Interaction Partners

Human Hydrogen Voltage-Gated Channel 1 (HVCN1) interaction partners

  1. Our data demonstrated that the expression of Hv1 in pancreatic islet beta-cells regulates insulin (show INS Antibodies) secretion through regulating Ca(2 (show CA2 Antibodies)+) homeostasis.

  2. The main properties of the voltage-gated proton channel (HV1) are described in this review, along with what is known about how the channel protein structure accomplishes its functions. [review]

  3. Hv1 activity displays hysteresis

  4. A shorter isoform of HVCN1 with enhanced gating is specifically enriched in malignant B cells.

  5. Divalent metal binding causes a conformational change in human the Hv1 c-terminal domain.

  6. analysis of of the C-terminal domain of voltage-gated proton channel HV1 and the thermodynamic characteristics of Zn(2) binding to this domain

  7. Salt bridge networks and the hydrophobic plug function as the gate in Hv1 channels; outward movement of the fourth transmembrane segment leads to the opening of this gate.

  8. Results suggest that Hv1 may be used as a potential biomarker for diagnosis and prognosis of colorectal carcinoma, and a potential target for anticancer drugs in colorectal cancer therapy.

  9. inhibition of Hv1 activity via Zn(2+) ions can effectively retard the cancer growth and suppress the cancer metastasis by the decrease of proton extrusion and the down-regulation of gelatinase activity

  10. In the Hv1 voltage-gated channel a highly conserved phenylalanine is found in the charge transfer center.

Mouse (Murine) Hydrogen Voltage-Gated Channel 1 (HVCN1) interaction partners

  1. Alkalinity of neutrophil phagocytic vacuoles is modulated by HVCN1.

  2. The voltage-gated proton channel Hv1/VSOP inhibits neutrophil granule release

  3. Our data demonstrated that the expression of Hv1 in pancreatic islet beta-cells regulates insulin (show INS Antibodies) secretion through regulating Ca(2 (show CA2 Antibodies)+) homeostasis.

  4. Eosinophils require proton channel HVCN1 for optimal reactive oxygen species generation and prevention of activation-induced cell death.

  5. Functional expression of voltage-gated proton (Hv1) channels is characterized, for the first time, in mouse bone marrow-derived dendritic cells.

  6. inhibition of Hv1 function via knockdown of Hv1 expression can effectively retard cancer growth

  7. Hv1 channels maintain a physiological membrane potential during the respiratory burst of neutrophils by providing a compensating charge for the electrons transferred by NOX2 (show CYBB Antibodies) from NADPH (show FDXR Antibodies) to superoxide.

  8. Review of structural organization and gating of Hv1 channels discusses relationship between gating of Hvcn1 and the gating of ion-conducting pores recently discovered in the voltage-sensing domains of mutant voltage-gated potassium and sodium channels.

  9. HVCN1 -deficieent B cells show a defct in ROS production, which causes less signal transduction through impaired BCR-dependent oxidation of SHP-1.

  10. Hv1 channels truncated just downstream of R2 in the S4 segment retain most channel properties.

HVCN1 Antigen Profile

Protein Summary

This gene encodes a voltage-gated protein channel protein expressed more highly in certain cells of the immune system. Phagocytic cells produce superoxide anions which require this channel protein, and in B cells this same process facilitates antibody production. This same channel protein, however, can also regulate functions in other cells including spermatozoa. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with HVCN1

  • hydrogen voltage-gated channel 1 (hvcn1) antibody
  • hydrogen voltage-gated channel 1 (HVCN1) antibody
  • voltage-gated hydrogen channel 1 (hvcn1) antibody
  • hydrogen voltage-gated channel 1 (Hvcn1) antibody
  • 0610039P13Rik antibody
  • AI450555 antibody
  • BTS antibody
  • HV1 antibody
  • HVCN1 antibody
  • mVSOP antibody
  • RGD1310788 antibody
  • Vsop antibody
  • vsx1 antibody
  • zgc:92181 antibody

Protein level used designations for HVCN1

HV1 , voltage-gated hydrogen channel 1 , hydrogen voltage-gated channel 1 , voltage sensor domain-only protein

GENE ID SPECIES
436618 Danio rerio
452241 Pan troglodytes
496712 Xenopus (Silurana) tropicalis
608547 Canis lupus familiaris
616570 Bos taurus
778897 Ciona intestinalis
100152115 Sus scrofa
84329 Homo sapiens
74096 Mus musculus
416871 Gallus gallus
304485 Rattus norvegicus
496219 Xenopus laevis
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