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Hydroxysteroid (17-Beta) Dehydrogenase 10 Proteins (HSD17B10)

HSD17B10 encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. Additionally we are shipping HSD17B10 Antibodies (107) and HSD17B10 Kits (13) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HSD17B10 3028 Q99714
HSD17B10 15108  
HSD17B10 63864 O70351
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Top HSD17B10 Proteins at antibodies-online.com

Showing 10 out of 18 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$286.00
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,673.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,673.00
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Log in to see 3 to 4 Days
$2,524.50
Details
HOST_Human Human His tag   10 μg Log in to see 5 Days
$203.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$322.14
Details

HSD17B10 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, ,
Mouse (Murine)

Rat (Rattus)

Top referenced HSD17B10 Proteins

  1. Human HSD17B10 Protein expressed in Escherichia coli (E. coli) - ABIN666970 : Holzmann, Frank, Löffler, Bennett, Gerner, Rossmanith: RNase P without RNA: identification and functional reconstitution of the human mitochondrial tRNA processing enzyme. in Cell 2008 (PubMed)
    Show all 2 references for ABIN666970

More Proteins for Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) Interaction Partners

Human Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) interaction partners

  1. Data suggest that HSD10 plays a role in alterations of energy metabolism by regulating mtDNA content in colorectal carcinomas.

  2. upon exposure to E2, ERalpha (show ESR1 Proteins) rapidly localizes to mitochondria, in which it interacts with HSD17B10 to modulate the expression of mitochondrial RNA transcripts.

  3. Our findings demonstrate that overexpression of HSD10 accelerates pheochromocytoma cell growth, enhances cell respiration, and increases cellular resistance to cell death induction.

  4. Three HSD10 variants associated with neurodegenerative disorders are inactive with cardiolipin

  5. The authors demonstrate elevated amounts of unprocessed pre-tRNAs and mRNA transcripts encoding mitochondrial subunits indicating deficient RNase P activity in HSD10 disease.

  6. The study showed that pathogenic mutations impair SDR5C1-dependent dehydrogenation, tRNA processing and methylation.

  7. loss of HSD10 causes impaired mitochondrial precursor transcript processing which may explain mitochondrial dysfunction observed in HSD10 disease

  8. Defects in this gene are a cause of 17beta-hydroxysteroid dehydrogenase (show HSD17B7 Proteins) type 10 (HSD10) deficiency. The encoded protein does not exhibit generalized alcohol dehydrogenase (show AKR1A1 Proteins) activity as was previously thought.

  9. Significantly higher levels of SRD5A1 (show SRD5A1 Proteins), AKR1C2 (show AKR1C2 Proteins), AKR1C3 (show AKR1C3 Proteins), and HSD17B10 mRNA were however found in bone metastases than in non-malignant and/or malignant prostate tissue

  10. Inhibition of mitochondrial RNase P by beta-amyloid is an unspecific effect and is not mediated by beta-amyloid interaction with SDR5C1.

Mouse (Murine) Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) interaction partners

  1. that 17beta-HSD-10 is a major product of both fetal and adult-type Leydig cells.

  2. ABAD enhances Abeta (show APP Proteins)-induced cell stress via mitochondrial dysfunction.Amyloid-beta peptide (Abeta (show APP Proteins)) binding alcohol dehydrogenase (show AKR1A1 Proteins) (ABAD), an enzyme present in neuronal mitochondria, is a cofactor facilitating Abeta (show APP Proteins)-induced cell stress.

HSD17B10 Protein Profile

Protein Summary

This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

Gene names and symbols associated with HSD17B10

  • hydroxysteroid (17-beta) dehydrogenase 10 (HSD17B10)
  • hydroxysteroid (17-beta) dehydrogenase 10 (hsd17b10)
  • hydroxysteroid (17-beta) dehydrogenase 10 (LOC100342235)
  • hydroxysteroid (17-beta) dehydrogenase 10 (Hsd17b10)
  • 17b-HSD10 protein
  • 17bHSD10 protein
  • ABAD protein
  • Ads9 protein
  • CAMR protein
  • DUPXp11.22 protein
  • ERAB protein
  • Hadh2 protein
  • HCD2 protein
  • hsd10 protein
  • HSD17B10 protein
  • im:6899159 protein
  • MHBD protein
  • MRPP2 protein
  • MRX17 protein
  • MRX31 protein
  • MRXS10 protein
  • SCHAD protein
  • SDR5C1 protein
  • wu:fj61f03 protein
  • zgc:101605 protein

Protein level used designations for HSD17B10

hydroxysteroid (17-beta) dehydrogenase 10 , 3-hydroxyacyl-CoA dehydrogenase type-2 , hydroxyacyl-Coenzyme A dehydrogenase, type II , 3-hydroxy-2-methylbutyryl-CoA dehydrogenase , AB-binding alcohol dehydrogenase , amyloid-beta peptide binding alcohol dehydrogenase , endoplasmic reticulum-associated amyloid beta-peptide-binding protein , mitochondrial RNase P subunit 2 , mitochondrial ribonuclease P protein 2 , short chain L-3-hydroxyacyl-CoA dehydrogenase type 2 , short chain dehydrogenase/reductase family 5C, member 1 , short chain type dehydrogenase/reductase XH98G2 , 17-beta-HSD 10 , 17-beta-hydroxysteroid dehydrogenase 10 , 3-hydroxyacyl-CoA dehydrogenase type II , hydroxyacyl-Coenzyme A dehydrogenase type II , mitochondrial RNase P protein 2 , type II HADH , amyloid beta-peptide binding protein , short chain L-3-hydroxyacyl-CoA dehydrogenase , hydroxyacyl-Coenzyme A dehydrogenase, type II hydroxyacyl-Coenzyme A

GENE ID SPECIES
425758 Gallus gallus
450078 Danio rerio
549265 Xenopus (Silurana) tropicalis
465649 Pan troglodytes
480930 Canis lupus familiaris
100342235 Oryctolagus cuniculus
3028 Homo sapiens
446903 Xenopus laevis
15108 Mus musculus
63864 Rattus norvegicus
281809 Bos taurus
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