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anti-Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3) Antibodies

This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. Additionally we are shipping HSD17B3 Kits (6) and HSD17B3 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HSD17B3 15487 P70385
HSD17B3 117182 O54939
HSD17B3 3293 P37058
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Top anti-HSD17B3 Antibodies at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometry analysis of K562 cells using 17-beta-HSD3 / HSD17B3 Antibody (Center) Cat.-No AP52111PU-N (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in formalin-fixed and paraffin-embedded human testis tissue reacted with 17-beta-HSD3 / HSD17B3 Antibody (Center) followed which was peroxidase conjugated to the secondary antibody, followed by DAB staining. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated ELISA, WB HSD17B3 polyclonal antibody (A01), Lot # 060614JCS1. Western Blot analysis of HSD17B3 expression in Raw 264.7. Western Blot detection against Immunogen (36.12 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of HSD17B3 Antibody (Center) (ABIN653468) in K562 cell line lysates (35 µg/lane). HSD17B3 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human testis tissue reacted with HSD17B3 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-HSD17B3 Polyclonal Antibody, Unconjugated (ABIN750928) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Formalin-fixed and paraffin embedded rat testis labeled with Anti-HSD17B3 Polyclonal Antibody, Unconjugated (ABIN750928) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Alkaline Phosphatase (AP) FACS, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit FITC IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

HSD17B3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-HSD17B3 Antibodies

  1. Human Polyclonal HSD17B3 Primary Antibody for ELISA, WB - ABIN561372 : Locke, Guns, Lubik, Adomat, Hendy, Wood, Ettinger, Gleave, Nelson: Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer. in Cancer research 2008 (PubMed)
    Show all 3 references for ABIN561372

  2. Human Polyclonal HSD17B3 Primary Antibody for EIA, FACS - ABIN950183 : Chakrabarti, Dudbridge, Kent, Wheelwright, Hill-Cawthorne, Allison, Banerjee-Basu, Baron-Cohen: Genes related to sex steroids, neural growth, and social-emotional behavior are associated with autistic traits, empathy, and Asperger syndrome. in Autism research : official journal of the International Society for Autism Research 2009 (PubMed)
    Show all 2 references for ABIN950183

  3. Human Polyclonal HSD17B3 Primary Antibody for WB - ABIN2785439 : Bertin, Dury, Ouellet, Pelletier, Labrie: Localization of the Androgen-Synthesizing Enzymes, Androgen Receptor, and Sex Steroids in the Vagina: Possible Implications for the Treatment of Postmenopausal Sexual Dysfunction. in The journal of sexual medicine 2014 (PubMed)

More Antibodies against HSD17B3 Interaction Partners

Mouse (Murine) Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3) interaction partners

  1. High 4-tert (show TERT Antibodies)-Octylphenol doses affect the cytoarchitecture of MA-10 Leydig cells as well as attenuate 3beta-HSD (show HAL Antibodies) and AR expression.

  2. Pubertal Cd exposure markedly reduced mRNA and protein levels of testicular StAR, P450scc (show CYP11A1 Antibodies), P450 (show POR Antibodies)(17alpha) and 17beta-HSD (show HSD17B1 Antibodies) in mice.

Human Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3) interaction partners

  1. Mutation G133R in HSD17B3 results in almost complete loss of enzyme activity since it interferes with binding of cofactor NADPH (show NQO1 Antibodies).

  2. Mutations in the HSD17B3 gene is associated with Disorders of Sex Development.

  3. Mutations in the HSD17B3 gene is associated with Disorders of Sex Development.

  4. Expression of the genes HSD3B1 (show HSD3B1 Antibodies), HSD17B3, and SRD5A2 (show SRD5A2 Antibodies) was significantly increased in BPH (show GLI3 Antibodies) tissues compared to normal adjacent prostate tissues.

  5. Missense mutation in HSD17B3 gene in a 46, XY adolescent is associated with primary amenorrhea and virilization at puberty

  6. 38% of unrelated 46,XY females with unknown diagnosis in the study have HSD17B3 mutations predicted to cause HSD17B3 deficiency.

  7. These results suggest that the HSD17B3 G289S polymorphism may be a potential risk modifier for hypospadias.

  8. 68 males with testicular 17beta-HSD deficiency were identified among a highly inbred Arab population in Israel as affected with male pseudohermaphroditism. [Review]

  9. The H8 haplotype of the HSD17B3 gene was significantly associated with increased risks of acne vulgaris in Han Chinese from the Southwest China.

  10. Case Report: rare form of 46,XY disorders of sexual development, associated to a novel gene nonsense mutation of HSD17B3 gene.

HSD17B3 Antigen Profile

Protein Summary

This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.

Gene names and symbols associated with HSD17B3

  • hydroxysteroid (17-beta) dehydrogenase 3 (Hsd17b3) antibody
  • hydroxysteroid (17-beta) dehydrogenase 3 (HSD17B3) antibody
  • EDH17B3 antibody
  • SDR12C2 antibody

Protein level used designations for HSD17B3

17(beta)HSD type 3 , 17-beta-HSD 3 , 17-beta-hydroxysteroid dehydrogenase type 3 , testicular 17-beta-hydroxysteroid dehydrogenase , testosterone 17-beta-dehydrogenase 3 , 17beta-HSD , estradiol 17 beta-dehydrogenase 3 , 17-beta-HSD3 , short chain dehydrogenase/reductase family 12C, member 2

GENE ID SPECIES
15487 Mus musculus
117182 Rattus norvegicus
3293 Homo sapiens
100513224 Sus scrofa
616934 Bos taurus
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