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Hydroxysteroid (17-Beta) Dehydrogenase 7 Proteins (HSD17B7)

HSD17B7 encodes an enzyme that functions both as a 17-beta-hydroxysteroid dehydrogenase (EC 1.1.1.62) in the biosynthesis of sex steroids and as a 3-ketosteroid reductase (EC 1.1.1.270) in the biosynthesis of cholesterol (Marijanovic et al., 2003 [PubMed 12829805]).[supplied by OMIM, May 2010].. Additionally we are shipping HSD17B7 Antibodies (30) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HSD17B7 51478 P56937
HSD17B7 15490 O88736
Rat HSD17B7 HSD17B7 29540 Q62904
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Top HSD17B7 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

HSD17B7 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,
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More Proteins for Hydroxysteroid (17-Beta) Dehydrogenase 7 (HSD17B7) Interaction Partners

Pig (Porcine) Hydroxysteroid (17-Beta) Dehydrogenase 7 (HSD17B7) interaction partners

Human Hydroxysteroid (17-Beta) Dehydrogenase 7 (HSD17B7) interaction partners

  1. 17beta-HSD1 (show SPAG8 Proteins) and 17beta-HSD7 are principal reductive 17beta-hydroxysteroid dehydrogenases and major players in the viability of estrogen-dependent breast cancer cells.

  2. The transcriptional activity of the HSD17B7 gene containing the G allele is higher than that of the C allele. This difference in HSD17B7 expression may regulate the risk of peripheral edema as an adverse reaction induced by estramustine phosphate sodium

  3. Data show that apicidin significantly lowers HSD17B1 (show HSD17B1 Proteins) transcript and protein levels in endometrial adenocarcinoma cells, with no significant effect on HSD17B1 (show HSD17B1 Proteins) transcript stability.

  4. estradiol stimulates HSD17B7 transcriptional activity in breast cancer cells through a novel mechanism requiring NF1 (show NF1 Proteins) and strongly suggest a positive feedback mechanism, increasing estradiol synthesis causing growth of estrogen-dependent breast cancers

  5. increased expression of HSD17B7 is associated with breast cancer.

  6. HSD17B7 is a novel candidate for inborn errors of cholesterol metabolism

  7. The identified proximal promoter regions of both human and murine HSD17B7 genes contain multiple transcription factor binding sites and show strong similarity to cholesterogenic genes.

  8. Results provide unequivocal evidence for a role of 17beta-hydroxysteroid dehydrogenase type-7 in cholesterol biosynthesis.

  9. 17beta-hydroxysteroid dehydrogenase type 7(17beta-HSD (show HSD17B3 Proteins) type 7)was significantly upregulated in ovarian tissue of patients with ovarian endometriosis.

  10. 17-beta hydroxysteroid dehydrogenase type 7 (HSD17B7) -shRNA sequences were designed and tested for their effectiveness.

Mouse (Murine) Hydroxysteroid (17-Beta) Dehydrogenase 7 (HSD17B7) interaction partners

  1. a recessive mutation, rudolph, that causes abnormal forebrain development was identified in hydroxysteroid (17-beta) dehydrogenase 7 gene, an enzyme necessary for cholesterol biosynthesis.

  2. Hsd17b7 activity is essential for fetal de novo cholesterol synthesis and for neuroectodermal survival and cardiovascular differentiation in early mouse embryos

  3. The identified proximal promoter regions of both human and murine HSD17B7 genes contain multiple transcription factor binding sites and show strong similarity to cholesterogenic genes.

  4. Results provide unequivocal evidence for a role of 17beta-hydroxysteroid dehydrogenase type-7 in cholesterol biosynthesis.

  5. Data show that prolactin receptor-associated protein (show S100A6 Proteins)/17beta-hydroxysteroid dehydrogenase type 7 plays an important role in fetal survival and embryonic development in mice.

HSD17B7 Protein Profile

Protein Summary

HSD17B7 encodes an enzyme that functions both as a 17-beta-hydroxysteroid dehydrogenase (EC 1.1.1.62) in the biosynthesis of sex steroids and as a 3-ketosteroid reductase (EC 1.1.1.270) in the biosynthesis of cholesterol (Marijanovic et al., 2003

Gene names and symbols associated with HSD17B7

  • hydroxysteroid (17-beta) dehydrogenase 7 (HSD17B7)
  • hydroxysteroid (17-beta) dehydrogenase 7 (hsd17b7)
  • hydroxysteroid (17-beta) dehydrogenase 7 (Hsd17b7)
  • AI266814 protein
  • MGC114978 protein
  • PRAP protein
  • SDR37C1 protein
  • zgc:153977 protein

Protein level used designations for HSD17B7

3-keto-steroid reductase , 17-beta hydroxysteroid dehydrogenase , hydroxysteroid (17-beta) dehydrogenase 7 , 17-beta-hydroxysteroid dehydrogenase type 7 , 3-keto-steroid reductase-like , 17 beta-hydroxysteroid dehydrogenase type VII , 17-beta-HSD 7 , 17-beta-hydroxysteroid dehydrogenase 7 , 17beta hydroxysteroid dehydrogenase , estradiol 17-beta-dehydrogenase 7 , short chain dehydrogenase/reductase family 37C, member 1 , PRAP , PRL receptor-associated protein , hydroxysteroid dehydrogenase 17 beta, type 7

GENE ID SPECIES
424367 Gallus gallus
505212 Bos taurus
548963 Xenopus (Silurana) tropicalis
609364 Canis lupus familiaris
734717 Xenopus laevis
747814 Pan troglodytes
768185 Danio rerio
100008778 Oryctolagus cuniculus
100155418 Sus scrofa
100446761 Pongo abelii
100587120 Nomascus leucogenys
51478 Homo sapiens
15490 Mus musculus
29540 Rattus norvegicus
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