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Hydroxysteroid (17-Beta) Dehydrogenase 8 Proteins (HSD17B8)

In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. Additionally we are shipping Hydroxysteroid (17-Beta) Dehydrogenase 8 Antibodies (42) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HSD17B8 14979 P50171
HSD17B8 7923 Q92506
HSD17B8 361802 Q6MGB5
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Top Hydroxysteroid (17-Beta) Dehydrogenase 8 Proteins at antibodies-online.com

Showing 10 out of 20 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Callithrix jacchus His tag   1 mg Log in to see 56 to 66 Days
$2,280.67
Details
Yeast Aggregatibacter actinomycetemcomitans His tag   1 mg Log in to see 56 to 66 Days
$2,616.17
Details
Yeast Shigella flexneri His tag   1 mg Log in to see 56 to 66 Days
$2,623.50
Details
Yeast Vibrio harveyi His tag   1 mg Log in to see 56 to 66 Days
$2,623.50
Details
Yeast REACT_Staphylococcus epidermis His tag   1 mg Log in to see 56 to 66 Days
$2,623.50
Details
Yeast Staphylococcus aureus His tag   1 mg Log in to see 56 to 66 Days
$2,629.00
Details

HSD17B8 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,
Rat (Rattus)

Top referenced Hydroxysteroid (17-Beta) Dehydrogenase 8 Proteins

  1. Human HSD17B8 Protein expressed in Escherichia coli (E. coli) - ABIN667899 : Rotinen, Celay, Alonso, Arrazola, Encio, Villar: Estradiol induces type 8 17beta-hydroxysteroid dehydrogenase expression: crosstalk between estrogen receptor alpha and C/EBPbeta. in The Journal of endocrinology 2008 (PubMed)
    Show all 2 references for ABIN667899

More Proteins for Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8) Interaction Partners

Cow (Bovine) Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8) interaction partners

  1. The complete CDS (show ABHD5 Proteins) sequence of the bovine FABGL gene was determined by homology cloning.

Human Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8) interaction partners

  1. The results indicate that aromatase (show CYP19A1 Proteins), 17beta-HSD (show HSD17B3 Proteins) type 7 and 17beta-HSD type 12 (show HSD17B12 Proteins), but not 17beta-HSD (show HSD17B3 Proteins) type 1, are commonly expressed in human breast cancer.

  2. transcription in liver is regulated by C/EBPbeta (show CEBPB Proteins)

  3. Expression of the human Ke 6 gene, 17beta-hydroxysteroid dehydrogenase (show HSD17B7 Proteins) type 8, in E. coli and the substrate specificity of the expressed protein were examined. The tissue distribution of mRNA expression of the human Ke 6 gene was also studied.

  4. ERalpha (show ESR1 Proteins) is involved in the transcriptional regulation of HSD17B8 gene in response to E2 through its interaction with C/EBPbeta (show CEBPB Proteins).

  5. Hs17beta-HSD8 (show CCDC91 Proteins) and HsCBR4 show a strong genetic interaction in vivo in yeast, where, only if they are expressed together, they rescue the respiratory deficiency and restore the lipoic acid content of oar1Delta cells.

  6. HSD17B8 mRNA is expressed in human skin, at lower levels in face vs arm or hip. HSD17B8 levels are not altered by topical 17-beta-estradiol treatment.

Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8) Protein Profile

Protein Summary

In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.

Gene names and symbols associated with HSD17B8

  • hydroxysteroid (17-beta) dehydrogenase 8 (hsd17b8)
  • hydroxysteroid (17-beta) dehydrogenase 8 (HSD17B8)
  • H2-K region expressed gene 6 (H2-Ke6)
  • hydroxysteroid (17-beta) dehydrogenase 8 (Hsd17b8)
  • D6S2245E protein
  • D17H6S112E protein
  • dJ1033B10.9 protein
  • FABG protein
  • Fabgl protein
  • H-2Ke6 protein
  • H2-KE6 protein
  • hke6 protein
  • Hsd17b8 protein
  • Ke-6 protein
  • Ke6 protein
  • RING2 protein
  • SDR30C1 protein
  • si:dz12f11.4 protein
  • zgc:112550 protein

Protein level used designations for HSD17B8

estradiol 17-beta-dehydrogenase 8 , FabG (beta-ketoacyl-[acyl-carrier-protein] reductase, E. coli) like , FabG-like protein , estradiol 17 beta-dehydrogenase 8 , 17-beta-HSD 8 , 17-beta-hydroxysteroid dehydrogenase 8 , 3-oxoacyl-[acyl-carrier-protein] reductase , estrogen 17-oxidoreductase , testosterone 17-beta-dehydrogenase 8 , ke-6 , protein Ke6 , really interesting new gene 2 protein , short chain dehydrogenase/reductase family 30C, member 1 , 17-beta-hydroxysteroid dehydrogenase type 8 , Estradiol 17-beta-dehydrogenase 8 , Testosterone 17-beta-dehydrogenase 8

GENE ID SPECIES
64815 Danio rerio
532422 Bos taurus
549425 Xenopus (Silurana) tropicalis
746685 Pan troglodytes
14979 Mus musculus
7923 Homo sapiens
361802 Rattus norvegicus
607895 Canis lupus familiaris
100154372 Sus scrofa
100415565 Callithrix jacchus
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