Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2 (HCN2) ELISA Kits

Hyperpolarization-activated cation channels of the HCN gene family, such as HCN2, contribute to spontaneous rhythmic activity in both heart and brain.[supplied by OMIM, Jul 2010].. Additionally we are shipping HCN2 Antibodies (72) and HCN2 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
HCN2 610 Q9UL51
HCN2 114244 Q9JKA9
HCN2 15166 O88703
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Top HCN2 ELISA Kits at antibodies-online.com

Showing 4 out of 7 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse 0.312-20 ng/mL   96 Tests Log in to see 2 to 3 Days
$867.90
Details
Mouse 0.188 ng/mL 0.312-20 ng/mL   96 Tests Log in to see 13 to 16 Days
$475.20
Details
Human
  96 Tests Log in to see 15 to 18 Days
$1,029.60
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Rat
  96 Tests Log in to see 15 to 18 Days
$1,029.60
Details

More ELISA Kits for HCN2 Interaction Partners

Human Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2 (HCN2) interaction partners

  1. beta2-adrenoceptors alone strongly enhanced the activity of HCN2 channels, and co-expression of odorant receptors further diversified the HCN2 channel activity.

  2. TRIP8b competes with a portion of the cAMP-binding site or distorts the binding site by making interactions with the binding pocket, thus acting predominantly as a competitive antagonist that inhibits the cyclic-nucleotide dependence of HCN channels.

  3. HCN2 has a role in maturation and processing of the amyloid precursor protein (show APP ELISA Kits)

  4. promoter methylation status does not appear to be a major determinant of HCN2 expression in normal and adenoid cystic carcinoma ( ACC )tissues. HCN2 hypomethylation is a biomarker of ACC and may play an important role in the carcinogenesis of ACC.

  5. Aged patients with sinus rhythm exhibited significantly higher expression levels of HCN2 and HCN4 channel mRNA and protein (P<0.05), but significantly lower expression levels of miR1 and 133, compared with those of adult patients with sinus rhythm.

  6. Data show that Rab8b (show RAB8B ELISA Kits)-interacting protein TRIP8b does not compete with cyclic AMP (show APRT ELISA Kits) for the same binding region of hyperpolarization activated cyclic nucleotide gated potassium channel 2 (HCN2).

  7. N-glycosylation is not required for HCN2 channels to function.

  8. Thermal hyperalgesia under chronic inflammatory conditions is mediated by HCN2 channels.

  9. Novel HCN2 mutation contributes to febrile seizures by shifting the channel's kinetics in a temperature-dependent manner.

  10. HCN2 polymorphism may play a role in chronic inflammatory periodontitis but not in peri (show PLIN1 ELISA Kits)-implantitis.

Mouse (Murine) Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2 (HCN2) interaction partners

  1. Data support a model in which the degree of facilitation of opening in the full-length HCN2 channel by a given ligand depends upon its ability to promote oligomerization of the C-linker/cyclic nucleotide-binding domain in solution.

  2. Mouse HCN2-expressing human mesenchymal stem cells are relevant biological models for the generation of biological pacemakers.

  3. the allosteric mechanism of different cyclic nucleotides on the cyclic nucleotide-binding domain of HCN2 and on channel gating, was investigated.

  4. HCN1 (show HCN1 ELISA Kits), HCN2, and HCN4 (show HCN3 ELISA Kits) subunits may have distinct physiological roles in the developing hippocampus.

  5. HCN2 channel activity reduces the repolarization reserve of the ventricular action potential and increases ectopic automaticity under pathological conditions such as excessive beta-adrenergic stimulation.

  6. This study demonstrated that Increased expression of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in reactive astrocytes following ischemia.

  7. fisetin is a partial agonist for HCN2 channels.

  8. HCN2 channel expression increases significantly during pregnancy, accelerating the heart rate.

  9. cAMP-dependent changes in the structure of the C-helix of a C-terminal fragment of HCN2 channels

  10. Dendritic expression of the h-channel subunit HCN1 (show HCN1 ELISA Kits), but not HCN2, was higher in the CA1 (show CA1 ELISA Kits) region of fmr1 (show FMR1 ELISA Kits)(-/y) mice.

HCN2 Antigen Profile

Antigen Summary

Hyperpolarization-activated cation channels of the HCN gene family, such as HCN2, contribute to spontaneous rhythmic activity in both heart and brain.

Gene names and symbols associated with HCN2

  • hyperpolarization activated cyclic nucleotide-gated potassium channel 2 (LOC428335) antibody
  • hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 (HCN2) antibody
  • hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 (Hcn2) antibody
  • hyperpolarization-activated, cyclic nucleotide-gated K+ 2 (Hcn2) antibody
  • BCNG-2 antibody
  • BCNG2 antibody
  • HAC-1 antibody
  • HAC1 antibody
  • HCN2 antibody
  • trls antibody

Protein level used designations for HCN2

hippocampus abundant transcript 1 , hippocampus abundant transcript 1 protein , hyperpolarization activated cyclic nucleotide-gated potassium channel 2 , brain cyclic nucleotide gated channel 2 , brain cyclic nucleotide-gated channel 2 , potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 , BCNG-2 , HAC-1 , hyperpolarization-activated cation channel 1

GENE ID SPECIES
428335 Gallus gallus
100297361 Bos taurus
100540153 Meleagris gallopavo
610 Homo sapiens
114244 Rattus norvegicus
15166 Mus musculus
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