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HCN3 encodes a multi-pass membrane protein that functions as a voltage gated cation channel. Additionally we are shipping HCN3 Antibodies (114) and many more products for this protein.
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Reduced HCN3 expression in aganglionic bowel suggests its potential role in Hirschsprung's disease pathophysiology.
KCTD3 is an accessory subunit of native HCN3 complexes
Genetic analysis in 48 Sudden unexpected death in epilepsy cases identified six novel and three previously reported nonsynonymous (amino acid changing) variants in HCN1 (show HCN1 Proteins) , HCN2 (show HCN2 Proteins), HCN3 and HCN4 (show HCN4 Proteins).
human HCN3 is not modulated by intracellular cAMP, in contrast to other HCN subtypes
This study demonstrated that Increased expression of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in reactive astrocytes following ischemia.
HCN3 contributes to the ventricular action potential waveform in the murine heart.
functional expression of HCN3 channels in thalamic intergeniculate leaflet neurons is crucial for intrinsic excitability and rhythmic burst firing
Although HCN channel function was greatly reduced in MitoPark DA neurons, mRNA levels for the isoforms most prominently expressed in DA-rich midbrain areas (HCN-3 (show CNGA3 Proteins) and HCN-1 (show CNGA1 Proteins)) were similar to those of the control mice.
GLI3 (show GLI3 Proteins) and Hh signaling controls Kit and Hcn3 expression and ureter peristalsis
the precise contribution of HCN4 to sinus node function still is unresolved, and in particular the role of HCN4 in human autonomic heart rate response has yet to be established.
The expression pattern of HCN isoforms in the olfactory bulb of mice, is described.
the distinct expression pattern in conjunction with the unusual biophysical properties implies that HCN3 may play an unique role in the body
Current through HCN2 (show HCN2 Proteins) and HCN3 channels confers regular and faster rhythmicity to mouse embryonic stem cells, which mirrors the developing embryonic mouse heart, and contributes to modulation of rhythmicity by autonomic stimulation.
This gene encodes a multi-pass membrane protein that functions as a voltage gated cation channel. The encoded protein is a member of a family of closely related cyclic adenosine monophosphate-binding channel proteins. Alternative splicing results in multiple transcript variants.
potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3
, hyperpolarization-activated cation channel 3
, hyperpolarization-activated, cyclic nucleotide-gated K+ 4